Lu Wang

ORCID: 0000-0003-0264-7046
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About
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Research Areas
  • Orthopedic Surgery and Rehabilitation
  • Anesthesia and Pain Management
  • Reconstructive Surgery and Microvascular Techniques
  • Cardiomyopathy and Myosin Studies
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Bone fractures and treatments
  • Medical Malpractice and Liability Issues
  • Congenital heart defects research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hemodynamic Monitoring and Therapy
  • CRISPR and Genetic Engineering
  • Cardiac Valve Diseases and Treatments
  • Elbow and Forearm Trauma Treatment
  • Shoulder Injury and Treatment
  • Congenital Heart Disease Studies
  • Atrial Fibrillation Management and Outcomes
  • Blood Pressure and Hypertension Studies
  • Pain Management and Opioid Use
  • Non-Invasive Vital Sign Monitoring
  • Peripheral Nerve Disorders
  • Head and Neck Surgical Oncology
  • Cardiovascular Function and Risk Factors
  • Pain Management and Treatment
  • Hydrogen's biological and therapeutic effects

Papworth Hospital NHS Foundation Trust
2025

First Affiliated Hospital of Zhengzhou University
2011-2024

University of Michigan
2018-2024

Peking University People's Hospital
2021-2024

Peking University
2021-2024

Sichuan Cancer Hospital
2024

Beijing Aerospace General Hospital
2024

Shanghai Pudong New Area Gongli Hospital
2023

Second Military Medical University
2023

Capital Medical University
2018-2023

<h3>Importance</h3> Optimal treatment for traumatic digit amputation is unknown. <h3>Objective</h3> To compare long-term patient-reported and functional outcomes between patients treated with revision or replantation amputations. <h3>Design, Setting, Participants</h3> Retrospective cohort study at 19 centers in the United States Asia. Participants were 338 individuals 18 years older amputations least 1 year of follow-up after treatment. enrolled from August 1, 2016, to April 12, 2018....

10.1001/jamasurg.2019.0418 article EN JAMA Surgery 2019-04-17

<h3>Objectives</h3> To investigate whether the plasma level of trimethylamine <i>N</i>-oxide (TMAO), a proatherosclerotic intestinal microbiota metabolite, can be predictor ischemic brain injury secondary to carotid artery stenting (CAS). <h3>Methods</h3> In this multicenter, prospective cohort study, we enrolled patients with severe stenosis (&gt;70%) who were prepared for CAS. Plasma TMAO was measured within 3 days before CAS, and MRI performed 1 after <h3>Results</h3> The mean age 268...

10.1212/wnl.0000000000005298 article EN Neurology 2018-03-14

Importance Casting is recommended for adults older than 65 years with distal radius fractures (DRFs) because similar long-term outcomes are achieved regardless of treatment. However, physiologically younger could benefit from operative DRF management despite advanced chronologic age. Objective To examine how age compares measures physiologic in treatment recovery. Design, Setting, and Participants This retrospective secondary analysis the Wrist Radius Injury Surgical Trial (WRIST) was...

10.1001/jamanetworkopen.2022.55786 article EN cc-by-nc-nd JAMA Network Open 2023-02-13

Abstract Background Pecto-intercostal fascial block (PIFB) provides analgesia for cardiac median sternotomy, but many patients complain of severe drainage pain that cannot be covered by PIFB. Rectus sheath (RSB) has been attempted to solve this problem, whether PIFB combined with RSB can achieve better is uncertain. Methods This was a single-center randomized controlled trial at Peking University People’s Hospital from September 22, 2022 December 21, 2022. Patients undergoing elective...

10.1186/s12871-023-02044-w article EN cc-by BMC Anesthesiology 2023-03-23

Background: Mounting evidence indicates that opioid-sparing anesthesia (OSA) decreases opioid-related adverse events. Our goal was to determine whether OSA might improve initial recovery after cardiac surgery. Methods: Data from patients who underwent elective heart surgery between July 2023 and 2024 were analyzed. Eligible divided into an group or a control group. Patients in the received 0.5 1 μg·kg −1 sufentanil ultrasound-guided nerve block anesthetic induction, whereas traditional...

10.15212/cvia.2024.0069 article EN cc-by-nc Cardiovascular Innovations and Applications 2025-01-01

Frozen shoulder (FS) is characterized by pain and significant loss of active passive motion. Strengthening exercises are among the standard used for FS. Neuromuscular exercise (NME) effectively improved range motion in shoulder. However, no prior research has looked into effects NME compared to strengthening FS rehabilitation. The aim present study was evaluate on (AROM) individuals with idiopathic frozen shoulder.Forty were randomly assigned either experimental group (NME regular physical...

10.1186/s12891-023-06173-8 article EN cc-by BMC Musculoskeletal Disorders 2023-01-20

Volume replacement with colloid solution and topical α-2 agonists may each moderate the progressive increase in intraocular pressure (IOP) during prone surgery. The authors tested hypotheses that prolonged surgery, IOP increases less goal-directed intravenous administration of 5% albumin than lactated Ringer's solution, agonist brimonidine placebo eye drops.Patients having complex spine surgery were factorially randomized to (n = 15); 16); 13); 16). was measured a pneumotonometer. primary...

10.1097/aln.0b013e3182475c10 article EN Anesthesiology 2012-02-09

Abstract Background Better protection can be provided during neurosurgery due to the establishment of somatosensory-evoked potential (SEP) and motor-evoked (MEP) monitoring technologies. However, some studies have showed that inhaled halogenated anesthetics a significant impact on neurophysiological monitoring. Methods A total 40 consecutive patients undergoing were randomly assigned two groups receiving anesthetics, either desflurane or sevoflurane. Multiples levels (concentrations 0.3, 0.6...

10.1186/s12871-021-01463-x article EN cc-by BMC Anesthesiology 2021-10-07

Background: Over 250,000 patients undergo bariatric surgery each year in the United States. Approximately 21% will subsequent body contouring after massive weight loss. Patients with prior are at a greater risk for complications relative to general population. However, it is unknown if type associated differential complication panniculectomy. Methods: A retrospective chart review of post-bariatric who underwent abdominal panniculectomy single large quaternary care center was performed....

10.1097/prs.0000000000011365 article EN Plastic & Reconstructive Surgery 2024-02-20

Various hypertension predictive models have been developed worldwide; however, there is no existing model for among Chinese rural populations.This a 6-year population-based prospective cohort in areas of China. Data was collected 2007-2008 (baseline survey) and 2013-2014 (follow-up from 8319 participants ranging age 35 to 74 years old. Specified gender were established based on multivariate Cox regression, Artificial Neural Network (ANN), Naive Bayes Classifier (NBC), Classification...

10.7189/jogh.09.020601 article EN cc-by Journal of Global Health 2019-11-24

Surgical treatment of closed distal radius fractures varies based on treatment, surgeon schedule, and patient preferences. The authors examined how timing technique impact surgeon-perceived procedural difficulty quality reduction, outcomes, complications.This was a retrospective study participants in the randomized, multicenter Wrist Radius Injury Trial with isolated unstable fractures. Participants were randomized to volar locking plate system, reduction percutaneous pinning, or external...

10.1097/prs.0000000000008416 article EN Plastic & Reconstructive Surgery 2021-09-20

Abstract Danon disease (DD) is caused by the absence or malfunction of lysosomal-associated membrane protein 2 (LAMP2). Although Lamp2 -deficient mice and DD patients have similar characteristics, these clear limitations are clinically inconsistent. The aim our paper to outline characteristics rats contrast this model with currently available mouse models. baseline levels some serum enzymes were elevated in y/− along hypercholesterolemia hyperglycaemia at 8 weeks. Echocardiography showed...

10.1038/s41598-018-24351-w article EN cc-by Scientific Reports 2018-04-26

Background Left ventricular hypertrophy (LVH) is an independent predictor of new‐onset atrial fibrillation. Whether LVH can predict the recurrence arrhythmia after radiofrequency catheter ablation (RFCA) in patients with paroxysmal fibrillation (PAF) remains unclear. Hypothesis PAF baseline‐electrocardiographic has a higher rate RFCA procedure compared those without LVH. Methods A total 436 undergoing first were consecutively enrolled and clustered into 2 groups based on electrocardiogram...

10.1002/clc.22957 article EN Clinical Cardiology 2018-03-31

Hypertrophic cardiomyopathy (HCM), the most common inherited heart disease, is frequently caused by mutations in β-cardiac myosin heavy chain gene (MYH7). Abnormal calcium handling and diastolic dysfunction are archetypical features of HCM MYH7 mutations. However, mechanism how leads to these remains unclear, which inhibits development effective therapies. Initially, cardiomyocytes were generated from induced pluripotent stem cells an eight-year-old girl diagnosed with carrying a MYH7(C.1063...

10.1016/j.ceca.2023.102822 article EN cc-by-nc-nd Cell Calcium 2023-11-08

Unstable pelvic fractures usually result from high-energy trauma. There are several treatment modalities available. The purpose of this study was to evaluate the clinical application a new less invasive ilioinguinal approach combined with minimally posterior technique in patients unstable fractures. We also address feasibility, validity, and limitations technique. Thirty-seven were treated our anterior ring approach, sacral approach. outcome measured using Majeed scoring system, quality...

10.1186/s12891-015-0635-x article EN cc-by BMC Musculoskeletal Disorders 2015-07-23

Abstract Background Minimally invasive direct coronary artery bypass (MIDCAB) surgery offers an effective option for disease (CAD) patients with the avoidance of median sternotomy and fast postoperative recovery. However, MIDCAB is still associated significant pain which may lead to delayed The erector spinae plane block (ESPB) a superficial fascial block. There have not been randomized controlled trials evaluating effects ESPB on analgesia patient recovery following surgery. We therefore...

10.1186/s13063-024-07925-0 article EN cc-by Trials 2024-01-19

Thumb carpometacarpal joint (CMC) osteoarthritis is the most symptomatic hand arthritis but long-term healthcare burden for managing this condition unknown. We sought to compare total cost and utilisation operative nonoperative treatments of thumb CMC arthritis.

10.1142/s2424835524500206 article EN The Journal of Hand Surgery (Asian-Pacific Volume) 2024-05-10

Object The aim of the study was to investigate safety, effectiveness, and peripheral nerve protection in ultrasound-guided microwave ablation (US-guided-MWA) for vascular malformations (VMs) closely related nerve. Materials methods From August 2019 February 2022, 31 patients with 39 VMs received US-guided-MWA. All lesions were confirmed be by imaging evaluation. Hydrodissection applied protect surrounding normal tissue, including nerves. followed up at 1day, 2 days, 3 1 week, month, months...

10.3389/fonc.2024.1146972 article EN cc-by Frontiers in Oncology 2024-06-04

The Wrist and Radius Injury Surgical Trial (WRIST) collaboration is the largest clinical trial ever conducted in hand surgery. We applied data from this study to examine relationship between functional outcomes patient satisfaction after treatment of distal radial fractures. Patients aged 60 years older with isolated fractures were enrolled at 24 health systems. Grip strength arc wrist motion measured treatment. Michigan Hand Outcomes Questionnaire was used measure satisfaction. Receiver...

10.1177/1753193419878981 article EN Journal of Hand Surgery (European Volume) 2019-10-04

Abstract Background This study aimed to evaluate the predictive accuracy of superior vena cava collapsibility index measured by transesophageal echocardiography and compare with stroke volume variation FloTrac™/Vigileo™ in mechanically ventilated patients. Methods In prospective study, a total 60 patients were enrolled for elective general surgery under mechanical ventilation, where all received 10 ml/kg Ringer’s lactate. Five kinds related data recorded before after fluid challenge,...

10.1186/s13741-023-00298-z article EN cc-by Perioperative Medicine 2023-04-10
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