A5087128063- Fungal Biology and Applications
- Wound Healing and Treatments
- Microencapsulation and Drying Processes
- Polysaccharides and Plant Cell Walls
- Oral health in cancer treatment
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Metastasis and carcinoma case studies
- 3D Printing in Biomedical Research
- Phytochemistry and Bioactivity Studies
- Animal Nutrition and Physiology
- Proteins in Food Systems
- Coccidia and coccidiosis research
- Helminth infection and control
- Antioxidants, Aging, Portulaca oleracea
- Sphingolipid Metabolism and Signaling
- Medicinal Plants and Bioactive Compounds
- Traditional Chinese Medicine Analysis
- Advanced Nanomaterials in Catalysis
- Pesticide Exposure and Toxicity
- Polysaccharides Composition and Applications
- Selenium in Biological Systems
- Laser-Ablation Synthesis of Nanoparticles
- Oral and gingival health research
- NF-κB Signaling Pathways
Universidade Federal do Ceará
2019-2024
Intestinal mucositis, characterized by inflammatory and/or ulcerative processes in the gastrointestinal tract, occurs due to cellular and tissue damage following treatment with 5-fluorouracil (5-FU). Rutin (RUT), a natural flavonoid extracted from Dimorphandra gardneriana, exhibits antioxidant, anti-inflammatory, cytoprotective, gastroprotective properties. However, effect of RUT on intestine, especially mucositis promoted antineoplastic agents, has not yet been reported. In this study, we...
Intestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), chemotherapeutic agent used for cancer treatment. Troxerutin (TRX), semi-synthetic flavonoid extracted from Dimorphandra gardneriana, has been reported as potent antioxidant and anti-inflammatory agent. In the present study, we aimed to evaluate effect of TRX on 5-FU-induced intestinal mucositis. Swiss mice were randomly divided into seven groups: Saline, 5-FU, TRX-50, TRX-100, TRX-150, Celecoxib (CLX), CLX...
The known biotechnological properties of chitosan and the recent biological activities attributed to polysaccharides from Agaricus brasiliensis have been interest obtain films constituted by these two polymers.The glucans obtained mushroom inhibited about 96.5% ferrous ion, besides not promoting a significant increase lactate dehydrogenase enzyme (LDH), which indicates that polysaccharide is able inhibit production radical species also presents low cytotoxicity systems.The results...
Abstract This work aimed the development and evaluation of wound healing activity films based on sodium alginate, polyvinyl alcohol (PVA) Ca 2+ loaded with Agaricus blazei Murill hydroalcoholic extract (AbE). Firstly, AbE was prepared using a previously standardized methodology. The were by casting technique cross‐linked CaCl 2 as cross‐linking agent. physicochemical, morphological water vapor barrier properties analyzed pre‐clinical efficacy investigated against cutaneous model in mice....
Abstract This work aimed to evaluate the in vitro anthelmintic effect of carvone nanoemulsions on Haemonchus contortus . Three R-carvone were prepared: uncoated homogenized a sonicator (UNAlg-son) and an ultrahomogenizer (UNAlg-ultra) sodium alginate-coated (CNAlg-ultra). The physicochemical characterizations carried out. activity was evaluated using egg hatch test (EHT), larval development (LDT) adult worm motility (AWMT). Changes cuticle induced H. by scanning electron microscopy (SEM)....