A5065829899- Obesity, Physical Activity, Diet
- Pneumonia and Respiratory Infections
- Nutritional Studies and Diet
- Health and Lifestyle Studies
- Respiratory viral infections research
- Asthma and respiratory diseases
- Physical Activity and Health
- Bacterial Infections and Vaccines
- Congenital Diaphragmatic Hernia Studies
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Pediatric Urology and Nephrology Studies
- Pleural and Pulmonary Diseases
- Consumer Attitudes and Food Labeling
- Urological Disorders and Treatments
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Glaucoma and retinal disorders
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Eating Disorders and Behaviors
- Inhalation and Respiratory Drug Delivery
- Respiratory and Cough-Related Research
- Long-Term Effects of COVID-19
- Allergic Rhinitis and Sensitization
Universidad de Navarra
2011-2025
Complejo Hospitalario de Navarra
2016-2025
Navarre Institute of Health Research
2016-2025
Servicio Navarro de Salud
2014-2025
Universidad Publica de Navarra
2021-2025
Boston Children's Hospital
2023
Harvard University
2023
Centro de Investigación Biomédica en Red
2011-2023
Spanish National Cancer Research Centre
2023
Hospital Universitario de Guadalajara
2023
Chronic neutrophilic leukemia (CNL) and atypical chronic myeloid (aCML) are rare disorders that challenging with regard to diagnosis clinical management. To study the similarities differences between these disorders, we undertook a multicenter international of one largest case series (CNL, n = 24; aCML, 37 cases, respectively), focusing on mutational profiles (n 53 molecular data) diseases. We found no in presentations or outcomes both entities. As previously described, CNL aCML share...
Coinfection with hepatitis C virus (HCV) and human immunodeficiency (HIV) is a known risk factor for hepatotoxicity in patients receiving highly active antiretroviral therapy (HAART). The aim of this study was to evaluate the role HCV-related liver fibrosis HAART-associated hepatotoxicity.In prospective involving 107 who underwent biopsy, graded according 5 stages, from F0 (no fibrosis) F4 (cirrhosis). Hepatotoxicity defined as an increase levels aspartate aminotransferase alanine >5 times...
This cross-sectional study aimed to assess the impact of age and gender on 4 measures grip pinch force well elderly community dwellers provide normative values. The hypotheses were that affect these 2 factors might interact. Hand strength 224 seniors 65–92 years old was tested. Grip decreased in successively older groups past 65 years. Men’s exceeded women all groups. hand-force decline steeper than over successive groups, suggesting differences with age. Trends same for types grip-...
Objective Intravenous iron is widely used to treat deficiency in day-care units. Ferric carboxymaltose (FCM) allows administration of larger doses than sucrose (IS) each infusion (1000 mg vs. 200 mg). As FCM reduces the number infusions required but more expensive, we performed a cost-minimization analysis compare cost impact two drugs. Materials and Methods The dose 111 consecutive patients who received intravenous at gastrointestinal diseases unit from 8/2007 7/2008 were retrospectively...
Abstract Objective To assess the long-term relationship between tree nut consumption and risk of developing metabolic syndrome (MetS). Design Nut was collected using a validated 136-item FFQ. The MetS defined according to International Diabetes Federation American Heart Association/National Heart, Lung, Blood Institute harmonizing definition. association assessed with logistic regression models adjusting for potential confounders. We compared incidence extreme categories intake (≥2...
Objectives Understanding respiratory syncytial virus (RSV) morbidity may help to plan health care and future vaccine recommendations. We aim describe the characteristics temporal distribution of children diagnosed with RSV admitted in a Spanish hospital. Methods Descriptive study for which hospital discharges < 5 years age infection were analyzed. The information was extracted from discharge database reference pediatric northern Spain 2010–2011 2014–2015 seasons. Results Six hundred...
La Secretaría de Salud solicitó al Instituto Nacional Pública la conformación un grupo expertos académicos en etiquetado alimentos y bebidas, independientes libres conflictos interés, que tuvieran encomienda emitir una postura para contribuir desarrollo sistema frontal productos industrializados proporcione información útil facilitar decisión compra. utiliza mejor evidencia científica disponible recomendaciones convocados por organismos internacionales. Así, propuesta se centra el contenido...
Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe long-term pediatric with severe persistent allergic asthma receiving largest real-life cohort reported date.ANCHORS was a multicenter, observational, retrospective study conducted 25 Pediatric Allergy and Pulmonology units Spain. collected data < 18 years initiating between 2006 2018, from year prior initiation discontinuation or...
Introduction: Biologic therapies have revolutionized the management of severe asthma in pediatrics, offering targeted options for specific inflammatory pathways. This study aimed to review current indications and availability biologics approved pediatric use as January 2025 analyze clinical experience a tertiary center managing this condition. Methods: A comprehensive available treating children was conducted, highlighting their key characteristics. Additionally, retrospective analysis...
ABSTRACT Long COVID is an emerging condition with important impact on the quality of life affected individuals. This study aims to analyse association between complete vaccination prior SARS‐CoV‐2 infection and subsequent development long COVID, including its symptoms their frequency through a retrospective case–control study. Cases included participants while controls were without but who had infection. Data collected self‐reported survey. The demonstrates significant lower incidence...
To assess the accuracy of self-reported data needed to constitute metabolic syndrome in University Navarra Follow-Up [Seguimiento Universidad de (SUN)] cohort.The SUN project is a multi-purpose prospective cohort, formed by more than 20,000 university graduates, followed-up using surface mail questionnaires every 2 years. In sample 287 cohort participants, on criteria define (waist circumference, blood pressure, triglycerides, high-density lipoprotein-cholesterol and glucose) were compared...
Background: Nonfebrile illness seizures may present in previously healthy children as afebrile associated with minor infections, such mild gastroenteritis or respiratory tract a genetic predisposition. For the novel human coronavirus SARS-CoV-2 causing COVID-19, fever, cough and gastrointestinal complaints are most common symptoms hyperimmune response be present. No detailed temporally neurological complications have been documented pediatric case series so far. Case description: We of...
Background The main objective was to evaluate the efficacy of intranasal photodynamic therapy (PDT) in SARS-CoV-2 mildly symptomatic carriers on decreasing infectivity period. SARS-CoV-2-specific immune-stimulating effects and safety were also analysed. Methods We performed a randomized, placebo-controlled, clinical trial tertiary hospital (NCT05184205). Patients with positive PCR last 48 hours recruited aleatorily assigned PDT or placebo. pneumonia excluded. Participants investigators...
Objective: The aim of this study was to examine the relationship ultra-processed food (UPF) intake with incidence glaucoma in a large sample Spanish university graduates followed prospectively. Methods: Prospective cohort using data from SUN Project. A final 19,225 participants (60.1% women) included study, mean age 38.2 years (standard deviation (SD) = 12.4). Participants were followed-up for time 12.9 (SD 5.4). Dietary measured 136-item semiquantitative food-frequency questionnaire. UPFs...
Abstract Respiratory syncytial virus (RSV) is an important cause of serious lower respiratory tract disease in infants. Several studies have shown evidence pointing to the genome host as factor determining susceptibility caused by RSV. We sequenced complete exomes 54 patients infected RSV that needed hospitalization due development severe bronchiolitis. The Iberian sample (IBS) from 1000 Genomes Project (1000G) was used control group; all association results were pseudo-replicated using...
Abstract Background An inverse association between total leisure-time physical activity (LTPA) and depression has been previously documented in the scientific literature. Our objective was to prospectively assess of LTPA with risk depression, focusing on several dimensions (intensity, duration type). Methods The SUN (Seguimiento Universidad de Navarra) project is a prospective cohort study formed by Spanish university graduates. A 15,488 adults (40.2% men, mean age 37 ± 12 years) initially...
The relationship between modifiable risk factors, such as diet and lifestyle, glaucoma remains controversial. We analyse the effect of Mediterranean lifestyle (ML) on incidence in "Seguimiento Universidad de Navarra" (SUN) Project.The SUN Healthy Lifestyle Score (SHLS) includes 10 healthy habits: never having smoked, moderate to high physical activity, adherence, alcohol consumption, low television exposure, no binge drinking, short afternoon napping, meeting up with friends, working at...
The association between parental perception of child's weight and their attitudes towards his/her dietary habits has not been reported yet. This study aimed to assess the underestimation habits. We conducted a cross-sectional analysis SENDO cohort participants recruited January 2015 June 2020. All information was collected through online questionnaires completed by parents. calculated crude multivariable-adjusted odds ratio (OR) 95% confidence intervals (CI) for unhealthy associated with...