A5081197693- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Genetics and Neurodevelopmental Disorders
- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Neurobiology of Language and Bilingualism
- Alcoholism and Thiamine Deficiency
- Peripheral Neuropathies and Disorders
- Ion channel regulation and function
- Chromatin Remodeling and Cancer
- Functional Brain Connectivity Studies
- Hemoglobinopathies and Related Disorders
- Ophthalmology and Eye Disorders
- Neurological disorders and treatments
- Neural and Behavioral Psychology Studies
- Neurological Complications and Syndromes
- Tactile and Sensory Interactions
- Genomic variations and chromosomal abnormalities
- Glycogen Storage Diseases and Myoclonus
- Autoimmune Neurological Disorders and Treatments
Hospital Universitario Puerta de Hierro Majadahonda
2022-2024
Neuroscience Institute
2024
Società Italiana di Reumatologia
2023
Hospital Clínico San Carlos
2013-2021
University of Milan
2021
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2018
Universidade Federal de São Paulo
2018
Hospital Universitario de Fuenlabrada
2018
ABSTRACT Anti‐N‐methyl‐D‐aspartate receptor encephalitis is a severe, potentially treatable, disorder and prognosis depends on early recognition prompt immunotherapy. We report case of anti‐N‐methyl‐D‐aspartate with atypical age gender, characteristic electroencephalographic pattern that supported the diagnosis. A 66‐year‐old male presented psychiatric disturbances focal seizures alteration consciousness, progressed to state akinetic mutism. Auxiliary tests were negative or non‐specific for...
Abstract Objective Cortical intracerebral electrical stimulation is an important tool for language mapping in the presurgical work‐up of patients with drug‐resistant focal epilepsy. Language stereo–electroencephalography (EEG) usually performed by high‐frequency stimulations (HFS: 50 Hz), whereas low‐frequency (LFS: 1 Hz) are considered useful primary cortices mapping. Little known literature about “intermediate” frequencies (IFS: 6–15 Hz). Our objective to explore clinical usefulness IFS...
Although clinical neuroscience and the of consciousness have long sought mechanistic explanations tactile-awareness disorders, insights are rare, mainly because difficulty depicting fine-grained neural dynamics underlying somatosensory processes. Here, we combined stereo-EEG responses to stimulation with lesion mapping patients a disorder, namely tactile extinction. Whereas present different temporal patterns, including early/phasic long-lasting/tonic activities, tactile-extinction...
• 7 of 9 patients with GGE reduced ≥ 50% their tonic–clonic seizure frequency on LCM. All remained free for > 1 year, and 2 them 5 years. In the patients, both Juvenile Absence Epilepsy, absences aggravated. One aggravation consisted a myoclonia absence status, in patient no history myoclonia. VEEG paralleled clinical improvement but didn't change case worsening.
Prolonged auras such as those of hemiplegic migraine or with brainstem aura may be extremely disabling. The availability effective treatments is limited, but two case reports described cessation the symptoms after a greater occipital nerve (GON) blockade.A 26-year-old woman history prolonged came to our office an episode motor and sensory 1 hour onset. Both muscle strength function started improve immediately GON anesthetic blockade, patient was fully relieved in 50 minutes.GON blockade...
Language lateralization in patients with focal epilepsy frequently diverges from the left-lateralized pattern that prevails healthy right-handed people, but mechanistic explanations are still a matter of debate. Here, we debate complex interaction between epilepsy, language lateralization, and functional neuroimaging techniques by introducing case patient unaware seizures preceded aphasia, whom video-EEG PET examination suggested presence cortical dysplasia right superior temporal gyrus,...