- Trigeminal Neuralgia and Treatments
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Migraine and Headache Studies
- Ophthalmology and Eye Disorders
- Botulinum Toxin and Related Neurological Disorders
- Neuroscience and Neuropharmacology Research
- Facial Nerve Paralysis Treatment and Research
- Cerebral Venous Sinus Thrombosis
- Dental Anxiety and Anesthesia Techniques
- Intraocular Surgery and Lenses
- Pain Mechanisms and Treatments
- Infectious Encephalopathies and Encephalitis
- Hemoglobinopathies and Related Disorders
- Meningioma and schwannoma management
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Ion channel regulation and function
- Sympathectomy and Hyperhidrosis Treatments
- Metabolism and Genetic Disorders
- Alzheimer's disease research and treatments
- Psychosomatic Disorders and Their Treatments
- Pneumonia and Respiratory Infections
- Suicide and Self-Harm Studies
- Ocular Surface and Contact Lens
Hospital Universitario Fundación Jiménez Díaz
2020-2023
Universidad Complutense de Madrid
2017-2021
Hospital Clínico San Carlos
2016-2021
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2016-2020
Universidad Rey Juan Carlos
2020
Abstract Objective The pharmacokinetics of brivaracetam ( BRV ), added to its effectiveness observed in animal models status epilepticus SE makes this drug attractive for use emergency situations. Our objective was evaluate the intravenous a multicenter study. Methods A retrospective registry cases treated with created. These patients were evaluated between January and December 2018 at seven hospitals Spain. Demographic variables, characteristics, concomitant drugs, loading doses, response...
Background Presently, there is no evidence to guide the acute treatment of migraine aura. We aimed describe effect greater occipital nerve (GON) anaesthetic block as a symptomatic for long-lasting (prolonged or persistent) Methods Patients who presented with aura lasting > 2 hours were consecutively recruited during one year at Headache Unit and Emergency Department tertiary hospital. All patients underwent bilateral GON bupivacaine 0.5%. followed up 24 hours. Results A total 22 auras...
Objective The aim of this study was to describe clinical features unique supratrochlear neuralgia. Background nerve supplies the medial aspect forehead. Due intricate relationship between supraorbital and nerves, neuralgic pain in region has been traditionally attributed No cases neuralgia have reported so far. Methods From 2009 through 2016, we prospectively recruited patients with confined territory nerve. Results Fifteen (13 women, 2 men; mean age 51.4 years, standard deviation 14.9)...
Objective Our aim was to explore the views and experiences of a group Spanish men suffering from cluster headache (CH). Background CH has considerable effects on patients' quality life, impairs everyday activities, can modify lifestyle. This is first time experience patients with examined in clinical study using qualitative, phenomenological approach. Methods We conducted qualitative exploring how 20 male CH, followed at Headache Unit hospital, perceived their disease. Data were collected...
Timing in status epilepticus (SE) attention is probably the most relevant modifiable prognostic factor and may influence SE duration prognosis. We aimed to describe precise relationship between management timing, duration, prognosis of SE.Observational longitudinal prospective study on a cohort all patients diagnosed with admitted our tertiary hospital from September 2017 August 2019, 3-month follow-up. Univariate multivariable analyses were performed identify clinical timing variables...
Our aim was to report three new cases of lacrimal neuralgia and their response superficial nerve blocks.Lacrimal has been recently described as a pain in the territory supplied by nerve, at lateral upper eyelid and/or adjacent area temple. The is typically accompanied tenderness on palpation superoexternal angle orbit.Between January 2015 June 2016, we prospective identified among patients attending Headache Unit tertiary hospital. Anesthetic blocks were performed all inserting 30-G needle...
Background Infratrochlear neuralgia is a recently described painful cranial neuropathy that causes pain in the internal angle of orbit and medial upper eyelid, bridge nose and/or lacrimal caruncle. We aim to present seven new cases infratrochlear treated with anaesthetic nerve blocks. Methods Over an 18-month period, we prospectively identified among patients attending Headache Unit tertiary hospital. Anaesthetic blocks were performed by injecting 0.5 cc bupivacaine 0.5% at emergence above...
Background Epicrania fugax has been described as a primary headache. Nevertheless, symptomatic form was recently found in patient with skull base meningioma abutting the trigeminal nerve. Here we report on facial pain features of epicrania occurring after Wallenberg’s syndrome. Case A 53-year-old man suffered right-sided dorsolateral medullary ischaemic stroke. Nine months later, he presented brief electric shock-like paroxysms stemming from right eye and radiating to ipsilateral forehead,...
Background: Atypical odontalgia (AO) manifests as continuous pain in the region of one or several teeth, absence signs dental pathology. Currently, there is insufficient evidence to establish treatment guidelines for AO. The aim this study was describe effectiveness and safety with OnabotulinumtoxinA (OnabotA) on a series patients Methods: Nine AO (four males five females, aged between 31 77 years) received injections OnabotA pain. dosage used each procedure ranged 10 30 U, spread 4 12...
To date, no symptomatic forms of epicrania fugax (EF) have been reported. Here, we describe the first EF-type pain to be probably caused by an underlying disorder.A 77-year-old woman started suffering from left V1-V2 trigeminal neuralgia at 72 years age. Neurologic examination was normal. Magnetic resonance imaging (MRI) showed a middle sphenoid wing meningioma compressing nerve medially. After trying several neuromodulators, she received stereotactic radiotherapy. One month later, episodes...
Seizures are a frequent reason for admission to emergency departments and require early, precise diagnosis treatment. The objective of this study was describe the clinical prognostic characteristics series patients with seizures attended at our hospital's department.We performed retrospective, observational all who were admitted department by on-call neurology service between February August 2017.We included 153 patients, representing 9.9% neurological admissions. median age 58 years, 52.3%...
Objective We aim to report 4 patients with brief pain paroxysms whose clinical features remind of typical epicrania fugax (EF), except for the direction along a transverse trajectory. Background EF has been defined as paroxysmal head pain, stabbing quality, describing linear or zig‐zag trajectory across surface one hemicranium. Methods considered all attending headache outpatient office at 3 tertiary hospitals from March 2008 December 2015. identified total cases dynamic moving in coronal...
Introduction Epicrania fugax (EF) is a primary headache whose main feature the dynamic character of pain. EF pain typically moves across different dermatomes in linear or zigzag trajectory. Recently, facial variant has been described, with starting lower face and radiating upwards. Aim We report eight patients an EF-type location either upward downward radiation. Methods For each patient, we recorded relevant demographic clinical data. Magnetic resonance imaging (MRI) fast employing steady...
Background Epicrania fugax consists of brief paroxysms pain, which radiate in a line or zigzag trajectory across the surface scalp face. Methods A prospective, descriptive study was performed five patients presenting with an epicrania fugax-type pain extracephalic irradiation. Results All were women, and mean age at onset 59.8 (standard deviation, 10.9). They had unilateral electrical starting particular point head (parietal, n = 3; vertex, 1; frontal, 1) rapidly radiating downwards lineal...
Timing is one of the most important modifiable prognostic factors in management status epilepticus. Epilepsia partialis continua (EPC) a epilepticus subtype highly variable, occasionally prolonged, duration. The aim this study was to analyse relationship between EPC duration and outcomes.We performed an observational prospective all patients with admitted our tertiary hospital 1 September 2017 2018.The sample included 10 patients, whom 9 were women; median age 74 years. frequent aetiology...
The first description of epicrania fugax (EF) reported brief painful paroxysms that start in posterior regions the scalp and move forward to reach ipsilateral forehead, eye, or nose. A backward variation, wherein pain stems from frontal areas radiates scalp, has also been acknowledged. We report four patients with features reminiscent EF coexistence paroxysms.We considered all attending headache outpatient office at two tertiary hospitals March 2008 2016. enrolled fulfilling criteria for a...
Las crisis epilépticas son un motivo de ingreso frecuente en urgencias y requieren una actuación diagnóstico-terapéutica precoz precisa. Nuestro objetivo fue describir las características clínico-evolutivas serie pacientes con atendidos urgencias. Estudio observacional retrospectivo todos los que ingresaron fueron por neurología guardia, febrero a agosto 2017. Se incluyeron 153 pacientes, correspondientes al 9,9% del total neurológicas. La mediana edad 58 años, el 52,3% mujeres 51% tenía...