A5083555145- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Parkinson's Disease Mechanisms and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Migraine and Headache Studies
- Pain Mechanisms and Treatments
- Psychosomatic Disorders and Their Treatments
- Genetic Neurodegenerative Diseases
- Restless Legs Syndrome Research
- COVID-19 Clinical Research Studies
- Musculoskeletal pain and rehabilitation
- Trigeminal Neuralgia and Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Peripheral Neuropathies and Disorders
- Neurological diseases and metabolism
- Intensive Care Unit Cognitive Disorders
- Sympathectomy and Hyperhidrosis Treatments
- Dysphagia Assessment and Management
- Ginkgo biloba and Cashew Applications
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Ultrasound and Hyperthermia Applications
Hospital Clínico San Carlos
2018-2023
Neurosciences Institute
2023
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2018-2022
Hospital Universitario Fundación Jiménez Díaz
2022
Universidad Complutense de Madrid
2018-2022
Universidad Rey Juan Carlos
2021
American Headache Society
2020
New York Proton Center
2020
The pandemic of the coronavirus disease 2019 (COVID-19) has provoked a second pandemic, "long-haulers", i.e., individuals presenting with post-COVID symptoms. We propose that to determine presence symptoms, symptoms should appear after diagnosis SARS-CoV-2 infection; however, this situation some problems due fact not all people infected by receive such diagnosis. Based on relapsing/remitting nature following integrative classification is proposed: potentially infection related-symptoms (up...
This multicenter cohort study investigated the differences between coronavirus disease 2019 (COVID-19) related symptoms and post-COVID male female COVID-19 survivors. Clinical hospitalization data were collected from hospital medical records in a sample of individuals recovered at five public hospitals Spain. A predefined list was systematically assessed, but patients free to report any symptom. Anxiety/depressive levels sleep quality also assessed. Adjusted multivariate logistic regressions...
<b><i>Background:</i></b> Multicentre studies focussing on specific long-term post-COVID-19 symptoms are scarce. <b><i>Objective:</i></b> The aim of this study was to determine the levels fatigue and dyspnoea, repercussions daily life activities, risk factors associated with or dyspnoea in COVID-19 survivors at long term after hospital discharge. <b><i>Methods:</i></b> Age, gender, height, weight, hospitalization,...
Abstract This study investigated the prevalence of long-term musculoskeletal post-COVID pain and their risk factors in a large cohort COVID-19 survivors. A multicenter including patients hospitalised because 5 hospitals Madrid (Spain) during first wave pandemic was conducted. Hospitalisation clinical data were collected from medical records. Patients scheduled for telephone interview after hospital discharge collecting about pain. Anxiety/depressive levels sleep quality likewise assessed....
Objective To investigate the association of headache during acute phase SARS-CoV-2 infection with long-term post-COVID and other symptoms in hospitalised survivors. Methods A case-control study including patients first wave pandemic Spain was conducted. Patients reporting as a symptom age- sex-matched without participated. Hospitalisation clinical data were collected from medical records. scheduled for telephone interview 7 months after hospital discharge. Participants asked about list also...
Abstract This study investigated the association between COVID-related myalgia experienced by patients at hospital admission and presence of post-COVID symptoms. A case-control including hospitalised due to COVID-19 February 20 May 31, 2020, was conducted. Patients reporting without were scheduled for a telephone interview 7 months after discharge. Hospitalisation clinical data collected from medical records. list symptoms with attention musculoskeletal pain evaluated. Anxiety depressive...
This study compared associated-symptoms at the acute phase of infection and post-COVID-19 symptoms between individuals hospitalized with Wuhan, Alpha or Delta SARS-CoV-2 variant. Non-vaccinated because in one hospital during three different waves pandemic (Wuhan, Delta) were scheduled for a telephone interview. The presence was systematically assessed. Hospitalization clinical data collected from medical records. A total 201 patients infected Wuhan variant, 211 variant 202 assessed six...
Background and objective: Sex plays a role in Parkinson’s disease (PD) mechanisms. We analyzed sex difference manifestations among Spanish patients with PD. Patients Methods: PD who were recruited from the cohort COPPADIS January 2016 to November 2017 included. A cross-sectional two-year follow-up analysis conducted. Univariate analyses general linear model repeated measure used. Results: At baseline, data 681 (mean age 62.54 ± 8.93) fit criteria for analysis. Of them, 410 (60.2%) males 271...
The role of disease-modifying therapies in patients with autoimmune disorders during severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection is controversial. Immunocompromised could have a more disease-2019 (COVID-19) due to the absence an adequate immune response against SARS-CoV-2. However, that act on play protective by dampening cytokine-release syndrome. Fingolimod drug used for therapy multiple sclerosis (MS) through sequestration activated lymphocytes lymph nodes. We...
Quality of life (QOL) plays an important role in independent living Parkinson's disease (PD) patients, being crucial to know what factors impact QoL throughout the course disease. Here we identified predictors impairment PD patients from a Spanish cohort. recruited 35 centers Spain COPPADIS cohort January 2016, November 2017, were followed up during 2 years. Health-related (HRQoL) and global (GQoL) assessed with 39-item Questionnaire (PDQ-39) EUROHIS-QOL 8-item index (EUROHIS-QOL8),...
Objective To investigate the association of pre-existing migraine in patients hospitalised and who recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with presence post-coronavirus disease (COVID) symptoms. Background No study has investigated role as a risk factor for development post-COVID Methods A case-control including individuals during first wave pandemic (from February 20 to May 31, 2020) was conducted. Patients confirmed previous diagnosis were...
We compared the prevalence of musculoskeletal post-COVID pain between previously hospitalized COVID-19 survivors infected with historical, Alpha or Delta SARS-CoV-2 variant. Data about were systematically collected through a telephone interview involving 201 patients who had survived historical variant, 211 variant and 202 six months after hospital discharge. Participants recruited from non-vaccinated individuals due to infection in one Madrid (Spain) during three different waves pandemic...
Directional subthalamic stimulation in Parkinson's disease can increase threshold for adverse effects and widen the therapeutic window. However, selection of programming settings is time consuming, requiring a thorough monopolar clinical review. To overcome this, may be guided by intraoperatively recording local field potential beta oscillations (13-35 Hz).1) Evaluate whether power recorded predict clinically most effective directional contacts; 2) assess long-term outcomes between patients...
This study looked at differences in the presence of headache as an onset symptom coronavirus disease 2019 (COVID-19) and a post-COVID-19 individuals previously hospitalized owing to infection with Wuhan, Alpha, or Delta variants severe acute respiratory syndrome 2 (SARS-CoV-2).Headache can be present up 50% during phase SARS-CoV-2 10% subjects phase. There are no data on occurrence acute- according variants.A cross-sectional cohort was conducted. Unvaccinated for COVID-19 caused by Wuhan (n...
Constipation has been linked to cognitive impairment development in Parkinson's disease (PD).Our aim was analyze changes observed PD patients and controls from a Spanish cohort with regards the presence or not of constipation.PD recruited 35 centers Spain COPPADIS January 2016 November 2017 were followed-up during 2 years. The change status baseline (V0) 2-year follow-up assessed PD-CRS (Parkinson's Disease Cognitive Rating Scale). Subjects score ≥1 on item 21 NMSS (Non-Motor Symptoms Scale)...
Abstract This study investigated the association between serological biomarkers at hospital admission with development of long-term post-COVID pain symptoms in previously hospitalized coronavirus disease, 2019 (COVID-19) survivors. A cohort including patients hospitalised because COVID-19 1 urban Madrid (Spain) during first wave outbreak was conducted. Hospitalisation data, clinical and 11 were collected admission. Participants scheduled for an individual telephone interview after discharge...
Deep brain stimulation (DBS) is widely used for treatment of advanced, medication-refractory Parkinson's disease (PD). However, a significant proportion patients may suffer adverse effects; up to 10% will present one or more transient permanent neurobehavioral events.In our case study, 44-year-old woman diagnosed with PD 6 years previously who was suffering from motor fluctuations, dyskinesia, and freezing gait episodes submitted DBS implanted directional electrodes. Intraoperative local...
Objectives This study aimed to explore the views and experiences of a group Spanish patients suffering from new daily persistent headache (NDPH). Methods A qualitative descriptive was conducted with diagnosed NDPH. Purposeful sampling performed among attending specialized Headache Unit at 2 university hospitals between February 2017 December 2018. In total, 18 (11 women, 7 men; mean age 45.3, standard deviation 10.6) median duration illness 70 months (interquartile range, 24‐219) were...