Cristina Campos
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Parkinson's Disease Mechanisms and Treatments
- Autoimmune and Inflammatory Disorders Research
- Biosimilars and Bioanalytical Methods
- Peripheral Neuropathies and Disorders
- Ginkgo biloba and Cashew Applications
- Psoriasis: Treatment and Pathogenesis
- Glaucoma and retinal disorders
- Drug-Induced Adverse Reactions
- Kawasaki Disease and Coronary Complications
- Dementia and Cognitive Impairment Research
- Acute Ischemic Stroke Management
- Adolescent and Pediatric Healthcare
- Restless Legs Syndrome Research
- Retinal and Optic Conditions
- Cardiovascular and Diving-Related Complications
- Dysphagia Assessment and Management
- Obsessive-Compulsive Spectrum Disorders
- Chronic Disease Management Strategies
- Musculoskeletal synovial abnormalities and treatments
- Computational Drug Discovery Methods
- High Altitude and Hypoxia
- Abdominal vascular conditions and treatments
- Health Systems, Economic Evaluations, Quality of Life
University of Maryland, Baltimore
2025
Hospital General Universitario De Valencia
2002-2024
Hospital Universitario Virgen Macarena
2020-2023
Instituto de Biomedicina de Sevilla
2023
Hospital Universitario 12 De Octubre
2005
Abstract Objective To investigate the validity, reproducibility, and responsiveness of a simplified power Doppler ultrasound (PDUS) assessment joint inflammation compared with comprehensive 44‐joint PDUS in patients rheumatoid arthritis (RA) who started therapy biologic agent. Methods A total 160 active RA agent were prospectively recruited 18 Spanish centers. The underwent clinical laboratory blinded examination at baseline 6 months. 128 synovial sites 44 joints was performed. US synovitis...
To investigate the response to therapy of entheseal abnormalities assessed with power Doppler (PD) ultrasound (US) in spondyloarthropathies (SpA).A total 327 patients active SpA who were starting anti-tumor necrosis factor (TNF) prospectively recruited at 35 Spanish centers. A PDUS examination 14 peripheral entheses was performed by same investigator each center baseline and 6 months. The following elementary lesions enthesis (presence/absence): morphologic (hypoechogenicity and/or...
Quality of life (QOL) plays an important role in independent living Parkinson's disease (PD) patients, being crucial to know what factors impact QoL throughout the course disease. Here we identified predictors impairment PD patients from a Spanish cohort. recruited 35 centers Spain COPPADIS cohort January 2016, November 2017, were followed up during 2 years. Health-related (HRQoL) and global (GQoL) assessed with 39-item Questionnaire (PDQ-39) EUROHIS-QOL 8-item index (EUROHIS-QOL8),...
Rheumatic diseases are extensively managed with biological disease-modifying antirheumatic drugs (bDMARDs), but a notable proportion of patients withdraw in the long term because lack effectiveness, adverse events, or patient's decision. The present real-world analysis showed retention, and safety data collected Spanish BIOBADASER registry for psoriatic arthritis (PsA) axial spondyloarthritis (axSpA, including ankylosing spondylitis (AS) non-radiographic axSpA) treated secukinumab, human...
Objective To investigate the influence of COVID-19 vaccination on disease activity in rheumatoid arthritis (RA) and psoriatic (PsA) patients under targeted therapies. Patients methods 1765 vaccinated COVID-19, 1178 (66.7%) with RA 587 (33.3%) PsA from registry rheumatic diseases (COVIDSER) project, were included. Demographics, characteristics, Disease Activity Score 28 joints (DAS28) treatments collected. DAS28-based flare rates categorised distribution prevaccination post analysed by...
Abstract Background Patients with Rheumatoid Arthritis (RA) have a higher prevalence of comorbidities compared to the general population. However, implications multimorbidity on therapeutic response and treatment retention remain unexplored. Objectives: (a) To evaluate impact effectiveness first targeted synthetic or biologic disease-modifying antirheumatic drug (ts/bDMARD), in patients RA after 2-year follow-up; (b) investigate influence rate. Methods from BIOBADASER registry exposed...
Real-world studies are needed to identify factors associated with response biologic therapies in patients axial spondyloarthritis (SpA). The objective was assess sex differences tumor necrosis factor inhibitors (TNFi) and explore possible risk TNFi efficacy.A total of 969 SpA (315 females, 654 males) enrolled the BIOBADASER registry (2000-2019) who initiated a (first, second, or further lines) were studied. Statistical artificial intelligence (AI)-based data analyses used association other...
Abstract The study was aimed at analysing the frequency of impulse control disorders (ICDs) and compulsive behaviours (CBs) in patients with Parkinson’s disease (PD) subjects (CS) as well relationship between ICDs/CBs motor, nonmotor features dopaminergic treatment PD patients. Data came from COPPADIS-2015, an observational, descriptive, nationwide (Spain) study. We used validated Questionnaire for Impulsive-Compulsive Disorders Parkinson's Disease-Rating Scale (QUIP-RS) ICD/CB screening....
Abstract Background To evaluate the influence of disease activity on radiographic progression in axial spondyloarthritis (axSpA) patients treated with TNF inhibitors (TNFi). Methods The study included 101 axSpA from Spanish Register Biological Therapy Spondyloarthritides (REGISPONSERBIO), which had clinical data and assessment available. Patients were classified into 2 groups based duration TNFi treatment at baseline: (i) long-term (≥4 years) (ii) no (< 4 years). Radiographs scored by two...
Biologic therapy has changed the prognosis of patients with juvenile idiopathic arthritis (JIA). The aim this study was to examine pattern use, drug survival, and adverse events biologics in JIA during period from diagnosis adulthood. All included BIOBADASER (Spanish Registry for Adverse Events Biological Therapy Rheumatic Diseases), a multicenter prospective registry, diagnosed between 2000 2015 were analyzed. Proportions, means, SDs used describe population. Incidence rates 95% CIs...
Introdução: As lesões cerebrais graves e agudas necessitam de cuidados especializados. Pacientes com traumatismo cranioencefálico grave agudo, além dos acidentes vasculares encefálicas podem apresentar possibilidade complicações. A pressão intracraniana (PIC) elevada após essas condições é uma causa importante mortalidade. identificação, intervenção rápida início do tratamento para melhora prognóstico paciente. Objetivo: Analisar a importância cirúrgico na hipertensão intracraniana....
Obstructive sleep apnea (OSA) has been proposed as a factor that worsens stroke prognosis. Our aim was to determine if an OSA intervention could improve quality of life (QOL, first objective) and modified Rankin score (mRS, second objective).
The persistence of biologic (b) and targeted synthetic (ts) disease-modifying antirheumatic drugs(DMARDs) in monotherapy versus combination with conventional (cs) DMARDs is still a controversial topic rheumatic diseases. To clarify this issue, the retention initial treatment strategy b/tsDMARD csDMARD rheumatoid arthritis (RA), psoriatic (PsA) ankylosing spondylitis (AS) patients under real-life conditions was evaluated. Factors associated maintenance were analysed.