A5054465207- Epilepsy research and treatment
- Advanced Neuroimaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Pharmacological Effects and Toxicity Studies
- Hearing Impairment and Communication
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Cerebrospinal fluid and hydrocephalus
- Neonatal and fetal brain pathology
- Fetal and Pediatric Neurological Disorders
- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Genomics and Rare Diseases
- Action Observation and Synchronization
- Healthcare Systems and Public Health
- Optical Imaging and Spectroscopy Techniques
- Multiple Sclerosis Research Studies
- Hemodynamic Monitoring and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Language, Metaphor, and Cognition
- Renal and related cancers
- Rheumatoid Arthritis Research and Therapies
- Bone and Joint Diseases
- Multisensory perception and integration
- Molecular Biology Techniques and Applications
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
2023-2024
Ospedale San Carlo
2023-2024
Società Italiana di Reumatologia
2019-2023
Ospedale di Circolo e Fondazione Macchi
2017-2022
Aziende Socio Sanitarie Territoriale dei Sette Laghi
2021-2022
University of Genoa
2022
University of Pavia
2022
Neurosciences Institute
2022
Foundation Center
2022
Vita-Salute San Raffaele University
2022
This retrospective description of a surgical series is aimed at reporting on indications, methodology, results seizures, outcome predictors and complications from 20-year stereoelectroencephalography (SEEG) activity performed single epilepsy surgery centre. Prospectively collected data consecutive 742 SEEG procedures carried out 713 patients were reviewed described. Long-term seizure SEEG-guided resections was defined as binomial variable: absence (ILAE classes 1-2) or recurrence 3-6)...
Cingulate epilepsy (CE) is a rare type of focal that challenging to diagnose because the polymorphic semiology seizures, mimicking other types epilepsy, and limited utility scalp EEG.We selected consecutive patients with drug-resistant CE who were seizure-free after surgery, seizure onset zone (SOZ) confirmed in cingulate cortex (CC) by histology or stereo EEG. We analyzed subjective objective ictal manifestations using video recordings correlated anatomical CC subregion (anterior, anterior...
According to an evolutionist approach, laughter is a multifaceted behaviour affecting social, emotional, motor and speech functions. Albeit previous studies have suggested that high-frequency electrical stimulation (HF-ES) of the pregenual anterior cingulate cortex (pACC) may induce bursts laughter—suggesting crucial contribution this region cortical control behaviour—the complex nature implies outward connections from pACC reach affect network frontal limbic regions. Here, we studied...
Object To compare the occurrence of surgery-related complications in patients with childhood-onset focal epilepsy operated on paediatric or adult age. investigate risk factors for whole cohort, special attention to age at surgery and severe morbidity. Methods A cohort 1282 was retrospectively analysed. Occurrence complications, including a severely complicated course (SCC: surgical complication requiring reoperation and/or permanent neurological deficit death), compared between (<16...
OBJECTIVE Surgical treatment of drug-resistant epilepsy originating from the posterior quadrant (PQ) brain often requires large multilobar resections, and disconnective techniques have been advocated to limit risks associated with extensive tissue removal. Few previous studies described a tailored temporoparietooccipital (TPO) approach; only small series short postoperative follow-ups reported. The aim present study was approach PQ disconnections (MPQDs) for provide details about selection...
The functional anatomy of the anteromesial portion temporal lobe and its involvement in epilepsy can be explored by means intracerebral electrical stimulations. Here, we aimed to expand knowledge physiological pathophysiological symptoms conducting first large-sample systematic analysis 1529 stimulations this anatomical region. We retrospectively analysed all clinical manifestations induced 173 patients with drug-resistant focal at least one electrode implanted area. found that...
Background: Transverse myelitis (TM) is an inflammatory disorder that can be idiopathic or associated with central nervous system autoimmune/dysimmune diseases, connective tissue autoimmune post-infectious neurological syndromes. Prognosis of initial TM presentations uncertain. Objective: To identify outcome predictors in TM. Methods: Retrospective study on isolated at onset. Scores ⩾3 the modified Rankin scale (mRS) marked high disability. Results: A total 159 patients were identified. was...
Abstract BACKGROUND Accurate localization of the probable Epileptogenic Zone (EZ) from presurgical studies is crucial for achieving good prognosis in epilepsy surgery. OBJECTIVE To evaluate degree concordance at a sublobar derived noninvasive (video electroencephalography, EEG; magnetic resonance imaging, MRI; 18-fluorodeoxyglucose positron emission tomography FDG-PET, FDG-PET) and EZ estimated by stereoEEG, forecasting seizure recurrence long-term cohort patients with focal drug-resistant...
Language lateralization in patients with focal epilepsy frequently diverges from the left-lateralized pattern that prevails healthy right-handed people, but mechanistic explanations are still a matter of debate. Here, we debate complex interaction between epilepsy, language lateralization, and functional neuroimaging techniques by introducing case patient unaware seizures preceded aphasia, whom video-EEG PET examination suggested presence cortical dysplasia right superior temporal gyrus,...
Abstract The temporo-parietal junction (TPJ) is a cortical area contributing to multiplicity of visual, language-related and cognitive functions. In line with this functional richness, also the organization underlying white matter highly complex includes several bundles. few studies tackling date outcome neurological burdens surgical operations addressing TPJ document presence language disturbances visual field damages, latter hardly recovered in time. This observation advocates for...
Martin, Reinaldo Uribe San MD; Di Giacomo, Roberta Mai, Roberto Gozzo, Francesca Pelliccia, Veronica Mariani, Valeria Cardinale, Francesco Ciampi, Ethel Onofrj, Marco Tassi, Laura MD
Cyberbullying is a highly relevant phenomenon in adolescence. Making available sound cyberbullying scales different countries represents an important research issue. The present study aimed at extending previous findings on the Experience Scale (CES), assessing its psychometric properties sample of community-dwelling Italian adolescents (N = 2,112). Results showed that bifactor model was best fitting for both CES Perpetration and Victimisation scale items being provided also with measurement...
Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy. Parameters microstructural abnormalities derived from diffusion tensor imaging(DTI) have been reported to be helpful in differentiating between Left and Right TLE (L-TLE R-TLE) but few them compared L-TLE R-TLE with a voxelwise approach. In this study, whole brain tract based spatial statistical analysis was performed on DTI, kurtosis NODDI parameters 88 subjects identify specific white matter patterns alteration patient...