A5056868988- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Venous Thromboembolism Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Lung Cancer Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Helicobacter pylori-related gastroenterology studies
- Acute Myocardial Infarction Research
- Eosinophilic Esophagitis
- Delphi Technique in Research
- Approximation Theory and Sequence Spaces
- Dysphagia Assessment and Management
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal disorders and treatments
- Autoimmune and Inflammatory Disorders
- Gastrointestinal Tumor Research and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Pediatric Pain Management Techniques
- Clinical practice guidelines implementation
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Appendicitis Diagnosis and Management
Aarhus University
2021-2025
Aarhus University Hospital
2010-2025
Vejle Sygehus
2000
Abstract Background Antireflux surgery (ARS) has been found to be an effective treatment of gastro-esophageal reflux disease (GERD); however, the long-term effects are uncertain. This study aimed evaluate efficacy ARS on quality life, symptom severity, and use proton pump inhibitors (PPIs). Methods A validated GERD Health-Related Quality Life (GERD-HRQL) Questionnaire was sent 419 patients who underwent at Aarhus University Hospital from January 2012 April 2020. Patient records were reviewed...
The use of biological therapy (biologicals) is established in the treatment Crohn's disease. This study aimed to determine whether preoperative with biologicals associated an increased rate complications following surgery for disease intestinal anastomosis.All patients receiving and undergoing abdominal anastomosis or strictureplasty were identified at six tertiary referral centres. Demographic data, preoperative, operative postoperative details registered. Patients who treated within 2...
To assess the outcome of patients treated conservatively vs surgically during their first admission for sigmoid volvulus.We conducted a retrospective study 61 admitted to Aarhus University Hospital in Denmark between 1996 and 2011 incidence volvulus. The condition was diagnosed by radiography, sigmoidoscopy or surgery. Patients with surgery underwent either resection percutaneous endoscopic colostomy (PEC). Conservatively were managed without Data recorded into Microsoft Access database...
Background Oesophagectomy is a major oncological surgical procedure. Previous studies have shown wide range of bleeding during and after surgery, it unknown if perioperative associated with oesophagectomy purely in nature, or exacerbated by impaired haemostasis. We aimed to perform detailed investigation the coagulation patients undergoing due cancer. Methods The study was prospective including adult adeno- squamous cell carcinoma referred for intended curative oesophagectomy. Operative...
Since 2003, care for patients with oesophageal cancer has been centralized in a few dedicated centres Denmark. The aim of this study was to assess changes the treatment and outcome registered nationwide database.All diagnosed or gastro-oesophageal junction who underwent oesophagectomy Denmark between 2004 2013, were Danish clinical database carcinomas oesophagus, stomach (DECV database) included. Quality-of-care indicators, including number lymph nodes removed, anastomotic leak rate, 30-...
Abstract Background Surgery is the primary treatment that can offer potential cure for gastric cancer, but associated with significant risks. Identifying optimal surgical approaches should be based on comparing outcomes from well designed trials. Currently, trials report different outcomes, making synthesis of evidence difficult. To address this, aim this study was to develop a core outcome set (COS)—a standardized group important key international stakeholders—that reported by future in...
This article presents the anatomic and functional outcome of site-specific fascia repair for rectocele performed under local anesthesia. Methods. In this case series, 51 consecutive patients underwent Patients were subsequently reviewed in outpatient clinic.The mean follow-up period was 26.7 months. Pelvic examination revealed recurrence posterior vaginal wall prolapse 31% (16/51). Improvement emptying rectum achieved 23% (7/30), (7/30) relieved from constipation. One patient developed de...
Evaluation of the biliary tract is important in physiological, pathophysiological, and clinical studies. Although sphincter Oddi (SO) can be evaluated with manometry, this technique has several limitations. This may explain difficulties identifying pathophysiological mechanisms for dysfunction SO patients who benefit from certain therapies. To encompass problems methods such as functional lumen imaging probe (FLIP) have been developed to study GI sphincters. set about miniaturising FLIP...
The clinical benefits of totally minimal invasive esophagectomy (TIME) compared to open are documented and include reduced morbidity like pulmonary infections, shorter hospital stay an increase in short-term quality life. However, transition TIME can be associated with a learning curve increased morbidity. We report our implementation using 2-step approach, where the thoracoscopic part was added laparoscopic carefully selected patients. hypothesis that provides safe efficient without...
Background and Aims: The impact of body mass index on complications survival in patients undergoing esophagectomy has been extensively studied with conflicting results. In this study, we assess the following surgery for esophageal gastro-esophageal-junction cancer a Danish population. Material Methods: We identified 285 consecutive patients, who underwent curative-intended treatment period 2003–2010. manually reviewed electronic medical records all included study. Body was calculated as...
This study aimed to assess the impact of esophageal stenting on postoperative complications and survival in patients with obstructing gastroesophageal junction (GEJ) cancer. All treated without neoadjuvant therapy that had an R0-resection performed for GEJ cancer between January 2003 December 2010 were identified from a prospectively maintained database. Data stenting, mortality, morbidity, recurrence-free survival, complications, length hospital stay collected. Kaplan-Meier plots curves...
Acute cholecystitis can be the result of retention bile in gallbladder with possible secondary infection and ischaemia. The aim present study was to investigate whether internal drainage could protect against development acute a pig model.Twenty pigs were randomized either (drained) or not (undrained). Day 0 induced by ligation cystic artery duct together inoculation bacteria. Four days later killed gallbladders removed histologically scored for presence cholecystitis. Bile blood samples...
To investigate the referred pain area in patients 2-7 years after cholecystectomy order to test hypothesis that neuroplastic changes could give rise post pain.Forty were tested. Twenty five cholecystectomized due uncomplicated gallbladder stones and 15 because of acute cholecystitis. Sensitivity pinprick, heat, cold, pressure single repeated electrical stimulation was studied both control on contra lateral side abdomen.Five still intermittently suffered from pain. But objective 40 patients,...
Background Decisions regarding tumor staging, operability, resectability, and treatment strategy in patients with esophageal cancer are made at multidisciplinary team (MDT) conferences. We aimed to assess interobserver agreement from four national MDT conferences whether this would have a clinical impact.Methods A total of 20 were included across all upper gastrointestinal (GI) centers. Fully anonymized patient data distributed among the which decided on TNM category, curability, blinded...
<title>Abstract</title> <bold>Background</bold> The purpose of the study is to examine if prolonged thromboprophylaxis decreases risk thrombosis after intended curative surgery for oesophageal cancer. Study results are expected inform a guideline cancer surgery. perspective reduce morbidity and mortality in this critically ill patient group. Thrombosis second-most common cause death itself. depends on type, upper gastrointestinal cancers considered high risk. This further increased when...
Background: The surgical treatment of gastric and esophageal cancer in Denmark is centralized four specialized esophagogastric (EGC) centers. Patients are referred after an esophagogastroduodenoscopy (EGD) at a secondary healthcare facility. EGD repeated the EGC center before determining strategy. This multicenter retrospective study aimed to investigate quality EGDs performed facility evaluate clinical value when Methods: from three centers, who underwent esophagectomy or gastrectomy with...
During esophagectomy for malignancy, the anterior and posterior branches of vagus nerve are transected in order to achieve surgical radicality. This leads loss central nervous system-control pylorus which may lead delayed gastric emptying. We aimed investigate feasibility EndoFLIP technique assessment pyloric biomechanical properties patients undergoing esophagectomy.
Introduction: The aim of the present study was to investigate impact high age and comorbidities in relation postoperative complications, mortality, long-term survival patients undergoing surgery for adenocarcinoma esophagus gastro-esophageal junction (GEJ). Methods: A cohort 557 operated GEJ. Data were collected from a prospectively maintained database, Danish National Patient Registry, medical records. Univariate multivariate statistical models used analyze data after stratification...