A5019595657- Genomics and Phylogenetic Studies
- Bayesian Methods and Mixture Models
- Fish Ecology and Management Studies
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Peatlands and Wetlands Ecology
- Gaussian Processes and Bayesian Inference
- Evolution and Paleontology Studies
- Soil Carbon and Nitrogen Dynamics
- Esophageal and GI Pathology
- Marine and fisheries research
- Markov Chains and Monte Carlo Methods
- Image Retrieval and Classification Techniques
- Cancer-related molecular mechanisms research
- Statistical Methods and Bayesian Inference
- Marine Bivalve and Aquaculture Studies
- Climate change and permafrost
- Genetic diversity and population structure
- Music and Audio Processing
- Epigenetics and DNA Methylation
- Photonic Crystals and Applications
- Statistical Methods and Inference
- Medical Image Segmentation Techniques
- Sperm and Testicular Function
- Plant responses to water stress
Renmin Hospital of Wuhan University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Anhui Agricultural University
2020-2024
Wuhan University
2024
Ningbo University
2024
University of Macau
2024
Northeast Forestry University
2022-2024
East China Normal University
2016-2024
NetEase (China)
2024
Tianjin University of Science and Technology
2024
Long non-coding RNAs (lncRNAs) acting as competing endogenous (ceRNAs) play significant roles in the development of tumors, but functions specific lncRNAs and lncRNA-related ceRNA networks have not been fully elucidated for colon adenocarcinoma (COAD). In this study, we aimed to clarify lncRNA-microRNA (miRNA)-mRNA network potential lncRNA biomarkers COAD.We extracted data from The Cancer Genome Atlas (TCGA) identified COAD-specific mRNAs, miRNAs, lncRNAs. biological processes Gene Ontology...
A carbon-coated g-C3N4 nanotube (C-TCN) was constructed via the concurrent thermal polymerization of urea and carbonization glucose. When mass ratio glucose to 1/30, after precursors were concurrently recrystallized from water, partially dried, heated at 550 °C for 2 h, carbon/g-C3N4 hybrid (TCN-200) with high content could be successfully prepared, diameter which in range 45–80 nm. The formation mechanism C-TCN proposed as follows. As cocrystal form a stacked layered structure because...
We describe an "embarrassingly parallel" method for Bayesian phylogenetic inference, annealed Sequential Monte Carlo (SMC), based on recent advances in the SMC literature such as adaptive determination of annealing parameters. The algorithm provides approximate posterior distribution over trees and evolutionary parameters well unbiased estimator marginal likelihood. This unbiasedness property can be used purpose testing correctness simulation software. evaluate performance by reviewing...
Competing endogenous RNAs (ceRNAs) render the functions of long non‑coding (lncRNAs) more complicated during cancer processes. Potential lncRNA biomarkers and their roles as ceRNAs have not been clearly described for rectal adenocarcinoma (READ). In present study, we extracted data from The Cancer Genome Atlas (TCGA) including 167 tumor samples 10 adjacent non‑tumor samples. A total 202 lncRNAs, 190 microRNAs (miRNAs) 1,530 mRNAs were identified READ‑specific [log2(fold‑change)>2, FDR<0.01]....
Fresh semen is most commonly used in an artificial insemination of small ruminants, because low fertility rates frozen sperm. Generally, when developing and applying assisted reproductive technologies, sheep goats are classified as one species. In order to optimize sperm cryopreservation protocols goat, differences proteomes between ram buck necessary investigate, which may contribute function spermatozoa. the current work, a data-independent acquisition-mass spectrometry proteomic approach...
Glyoxalase I (GLYI) is a key enzyme in the pathway of glyoxalase system that degrades toxic substance methylglyoxal, which plays crucial part plant growth, development, and stress response. A total 19 GLYI genes were identified from cassava genome, distributed randomly on 11 chromosomes. These named MeGLYI-1–19 systematically characterized. Transcriptome data analysis showed MeGLYIs gene expression tissue-specific, MeGLYI-13 dominant expressed young tissues, while MeGLYI-19 mature tissues...
Background Postoperative pneumonia (POP) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) associated with increased mortality rates, prolonged hospitalization, and high medical costs. It currently understood that identifying early implementing aggressive treatment can significantly improve patients' outcomes. The primary objective of this study was to explore risk factors develop logistic regression model assesses the risks POP. Methods An internal cohort 613...
Soil organic carbon (SOC) and total nitrogen (TN) contents in different soil horizons are essential for vegetation growth crucial indicators to evaluate quality reclaimed mining areas. Compared with conventional wet chemistry methods, spectroscopy, including imaging can be used as a cost time-efficient analysis technique. However, there is great challenge combining laboratory point spectra hyperspectral imagery mapping vertical distribution of SOC TN (0–100 cm) soils. This primarily because...
During tumor progression, HER2 expression undergoes dynamic changes. Circulating cells (CTCs) can be used to monitor in real-time and hold potential for clinical application. This study aimed evaluate the consistency of between primary tumors CTCs patients with breast cancer (BC). We a previously established telomerase reverse transcriptase-based CTC detection method (TBCD) combined anti-HER2 antibody detect HER2-positive (HER2 + CTC) 4 ml peripheral blood from prior radiotherapy. The...
Genetic similarity is a measure of the genetic relatedness among individuals. The standard method for computing these matrices involves inner product observed variants. Such an approach inaccurate or impossible if genotypes are not available, densely sampled, poor quality (e.g., analysis extinct species). We provide new similarities individuals using phylogenetic trees. Our can supplement (or stand in for) computations based on genotypes. simulations suggesting that computed from trees...
The contamination of chronic wound with bacteria especially methicillin-resistant Staphylococcus aureus (MRSA) is considered as the major factor interferencing normal healing. There still remain great challenges in developing safe and effective dressings wide-spectrum antibacterial functions. Alginate hydrogel a common dressing for treatment. Copper one trace elements human body inherent activity. Traditional methods preparing structure-controlled copper-alginate matrix are difficult...
We study the sensitivity of fishery management per-recruit harvest rates which may be part a quantitative strategy designed to achieve some objective for catch or population size. use local influence analysis derive equations that describe how these reference are affected by perturbations productivity processes. These give basic theoretical understanding can used predict what likely impacts future changes in will be. Our results indicate more sensitive when equilibrium size per recruit, as...
Long non-coding RNA (lncRNA) regulated by abnormal DNA methylation (ADM-lncRNA) emerges as a biomarker for cancer diagnosis and treatment. This study comprehensively described the patterns of lncRNA in pan-cancer using data set The Cancer Genome Atlas (TCGA). Based on heterogeneity ADM-lncRNA pan-cancer, we constructed co-expression network (pADM-lncRNA) 10 cancers, highlighting combined action mode methylation, indicating internal connection among different cancers. Functional analysis...
Plant pectin methylesterases (PMEs) play crucial roles in regulating cell wall modification and response to various stresses. Members of the PME family have been found several crops, but there is a lack research into their presence cassava (Manihot esculent), which an important crop for world food security. In this research, 89 MePME genes were identified that separated two types (type-Ⅰ type-Ⅱ) according existence or absence pro-region (PMEI domain). The gene members unevenly located on 17...
Space partitioning methods such as random forests and the Mondrian process are powerful machine learning for multi-dimensional relational data, based on recursively cutting a domain. The flexibility of these is often limited by requirement that cuts be axis aligned. Ostomachion self-consistent binary space partitioning-tree were recently introduced generalizations with non-axis aligned in two dimensional plane. Motivated need tree cuts, we propose Random Tessellation Process (RTP), framework...
Abstract Background To investigate the survival benefit of concurrent chemoradiotherapy (CCRT) for patients with locally advanced esophageal squamous cell carcinoma (ESCC) during years intensity‐modulated radiotherapy (IMRT). Methods Medical records 1089 ESCC who received IMRT from January 2005 to December 2017 were retrospectively reviewed. A total 617 CCRT, 472 (RT) alone. Propensity score matching (PSM) method was used eliminate baseline differences between two groups. Survival and...