Leidiane Mazzardo‐Martins

ORCID: 0000-0003-0345-2339
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About
Contact & Profiles
Research Areas
  • Pain Mechanisms and Treatments
  • Pain Management and Treatment
  • Acupuncture Treatment Research Studies
  • Laser Applications in Dentistry and Medicine
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Myofascial pain diagnosis and treatment
  • Nerve injury and regeneration
  • Musculoskeletal pain and rehabilitation
  • Exercise and Physiological Responses
  • Pain Management and Placebo Effect
  • Chemical synthesis and alkaloids
  • Pediatric Pain Management Techniques
  • Neuropeptides and Animal Physiology
  • Vagus Nerve Stimulation Research
  • Ion channel regulation and function
  • Mindfulness and Compassion Interventions
  • Alkaloids: synthesis and pharmacology
  • Anesthesia and Pain Management
  • Nerve Injury and Rehabilitation
  • Essential Oils and Antimicrobial Activity
  • Bee Products Chemical Analysis
  • Cannabis and Cannabinoid Research
  • S100 Proteins and Annexins
  • Pharmacological Effects of Natural Compounds
  • Cancer, Stress, Anesthesia, and Immune Response

Universidade Federal de Santa Catarina
2013-2023

Universidade do Sul de Santa Catarina
2018-2023

Morpho (United States)
2016

Universidade do Estado de Santa Catarina
2012

An important issue in physical rehabilitation is how to protect from or reduce the effects of peripheral nerve injury. In present study, we examined whether ankle joint mobilization (AJM) would neuropathic pain and enhance motor functional recovery after axonotmesis model, AJM during 15 sessions every other day was conducted rats. Mechanical thermal hyperalgesia performance deficit were measured for 5 weeks. After weeks, performed morphological analysis quantified immunoreactivity CD11b/c...

10.1016/j.pain.2011.08.014 article EN Pain 2011-09-10

Pterodon pubescens Benth is a medicinal plant commonly used for therapeutic purposes in folk medicine rheumatic diseases' treatment. In the present work we analyzed chemical composition of oleaginous extract P. (OEPp) and extended antinociceptive effect OEPp evaluating its role on animal models acute chronic pain. The antiedematogenic effects (3–100 mg/kg, i.g.) were evaluated formalin test; mechanical allodynia postoperative pain complex regional syndrome type-I (CRPS-I) models; thermal...

10.1016/j.jep.2012.06.020 article EN publisher-specific-oa Journal of Ethnopharmacology 2012-06-21

Investigate whether ankle joint mobilization (AJM) decreases hypersensitivity in the mouse plantar incision (PI) model of postoperative pain as well to analyze possible mechanisms involved this effect.Experiment 1: PI male Swiss mice (25-35 g, N = eight animals per group) were subjected five sessions AJM, each lasting either 9 or 3 minutes. AJM movement was applied at a grade III defined by Maitland. Paw withdrawal frequency mechanical stimuli assessed before realization and after daily...

10.1111/j.1526-4637.2012.01438.x article EN Pain Medicine 2012-07-09

Physical therapists frequently use joint mobilization therapy techniques to treat people with musculoskeletal dysfunction and pain. Several studies suggest that endogenous adenosine may act in an analgesic fashion various pain states.The purpose of this study was investigate the contribution adenosinergic system on antihyperalgesic effect ankle (AJM).This a experimental study.To test hypothesis adrenosinergic is involved AJM, mice (25-35 g) submitted plantar incision surgery were used as...

10.2522/ptj.20120226 article EN Physical Therapy 2012-10-21

Neuropathic pain is severely debilitating and resistant to pharmacological approaches; therefore, the study of therapies complement its treatment especially relevant. In a case report study, light-emitting diode therapy (LEDT) has shown analgesic activity as well reduced expression pro-inflammatory cytokines in rabbit osteoarthritis model calcaneal tendinitis rats. Although LEDT stimulated morphofunctional recovery after nerve injury rats, effect against neuropathic not been tested.To that...

10.1002/j.1532-2149.2012.00280.x article EN European Journal of Pain 2013-01-21

Cedrus atlantica essential oil (CaEO) presents analgesic and anti-inflammatory sedative properties. However, it remains unknown whether CaEO alleviates acute postoperative pain.Here, we investigated the effect of on pain its mechanisms related to descending control in Swiss males mice induced by a plantar incision surgery (PIS) hindpaw.Inhalation (5', 30' or 60') markedly reduced mechanical hypersensitivity. This was prevented pre-treatment with naloxone p-chlorophenylalanine methyl ester...

10.1016/j.jep.2015.08.048 article EN publisher-specific-oa Journal of Ethnopharmacology 2015-09-04

Water immersion is widely used in physiotherapy and might relieve pain, probably by activating several distinct somatosensory modalities, including tactile, pressure, thermal sensations. However, the endogenous mechanisms behind this effect remain poorly understood. This study examined whether warm water therapy (WWIT) produces an antiallodynic a model of localized inflammation peripheral opioid, cannabinoid, adenosine receptors are involved effect. Mice were injected with complete Freund's...

10.1002/jnr.23461 article EN Journal of Neuroscience Research 2014-07-31

Abstract This study was designed to determine whether 3 weeks of gabapentin treatment is effective in alleviating neuropathic pain‐like behavior animal models complex regional pain syndrome type‐I and partial sciatic nerve ligation ( PSNL ). We investigated the contribution adenosine subtypes antihyperalgesic effect by examining caffeine, a non‐selective A 1 2 receptor antagonist or 1,3‐dipropyl‐8‐cyclopentylxanthine DPCPX ), selective subtype on this effect. Neuropathic produced unilateral...

10.1111/jns.12149 article EN Journal of the Peripheral Nervous System 2015-10-12
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