A5069561358- Breast Cancer Treatment Studies
- Advanced Radiotherapy Techniques
- MRI in cancer diagnosis
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Advances in Oncology and Radiotherapy
- Medical Imaging Techniques and Applications
- Reconstructive Surgery and Microvascular Techniques
- Intestinal and Peritoneal Adhesions
- Global Cancer Incidence and Screening
- Tissue Engineering and Regenerative Medicine
- Cancer survivorship and care
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Cutaneous Melanoma Detection and Management
- COVID-19 and healthcare impacts
- Education and Critical Thinking Development
- Hernia repair and management
- Immunotherapy and Immune Responses
- Economic and Financial Impacts of Cancer
- Emotional Intelligence and Performance
- Environmental Conservation and Management
- Spectroscopy Techniques in Biomedical and Chemical Research
- Cancer Genomics and Diagnostics
Amsterdam University Medical Centers
2019-2025
Vrije Universiteit Amsterdam
2019-2025
Zaans Medisch Centrum
2025
Amsterdam UMC Location Vrije Universiteit Amsterdam
2019-2024
Cancer Center Amsterdam
2023
Leiden University Medical Center
2012
Leiden University
2011
Novay
2005
The number of elderly women with breast cancer is increasing and will become a major health concern. However, little known about the optimal treatment for this age group. aim study was to describe time trends overall Dutch cohort an emphasis on differences between young patients.All adult female patients diagnosed in 1995-2005 were selected from Netherlands Cancer Registry. Relative excess risks death (adjusted stage, histology, treatment, grade) estimated using multivariate generalized...
Abstract Background Partial breast irradiation (PBI) is standard of care in low-risk cancer patients after breast-conserving surgery (BCS). Pre-operative PBI can result tumor downstaging and more precise target definition possibly resulting less treatment-related toxicity. This study aims to assess the pathologic complete response (pCR) rate one year MR-guided single-dose pre-operative patients. Methods The ABLATIVE-2 trial a multicenter prospective single-arm using ablative Patients ≥ 50...
In this pilot study, there was no statistical difference in diagnostic accuracy of fluorine 18 ( F) FES PET and F-FDG staging patients with grade 1 or 2, estrogen receptor–positive breast cancer P = .18).
Pre-clinical studies have shown that exercise can decrease tumour growth through mobilisation, activation, and increased infiltration of natural killer (NK) CD8+ T cells. It is currently unclear whether this be extrapolated to patients. Therefore, a pilot study was set up examine the feasibility obtaining an additional biopsy generate preliminary data on potential effects immune cell function infiltration. Twenty patients with stage I-III breast cancer receiving neoadjuvant chemotherapy were...
Background: Over the past decade, post-mastectomy radiotherapy (PMRT) is indicated more frequently in breast cancer treatment, especially patients with involved axillary lymph nodes. However, PMRT associated high complication rates and less satisfactory cosmetic results when combined immediate reconstructions. This has led to ongoing controversy regarding reconstruction radiotherapy, often postponing until long after been completed. Preoperative also known as neoadjuvant (NART), emerging a...
Preoperative partial breast irradiation (PBI) can increase accuracy of target volume definition and decrease irradiated volumes compared with postoperative PBI. In the ABLATIVE trial (NCT02316561), 15 36 patients achieved pathologic complete response 6 to 8 months after preoperative PBI breast-conserving surgery (BCS). We now present 5-year results. The is a Dutch prospective cohort study conducted in 4 hospitals. Women aged ≥50 years unifocal, nonlobular cancer, estrogen receptor-positive,...
Real‐time assessment of excised tissue may help to improve surgical results in breast tumor surgeries. Here, as a step towards this purpose, the potential second and third harmonic generation (SHG, THG) microscopy is explored. SHG THG are nonlinear optical microscopic techniques that do not require labeling generate 3D images with intrinsic depth‐sectioning at sub‐cellular resolution. Until now, technique had been applied on fixated or visualize stroma only, whereas most tumors start lobules...
Abstract Background Laparoscopic incisional hernia repair is increasingly performed worldwide and expected to be superior conventional open regarding hospital stay quality of life (QoL). The INCisional Hernia-Trial was designed test this hypothesis. Methods A multicenter parallel randomized controlled open-label trial with a superiority design conducted in six hospitals the Netherlands. Patients primary or recurrent hernias were by computer-guided block-randomization undergo either...
BackgroundWire-guided localization (WGL) of early breast cancer can be facilitated using multiple wires, which is called bracketing wire-guided (BWL). The primary aim this study to compare BWL and conventional WGL regarding minimization resection volumes without compromising margin status. Secondly, evaluated as an alternative method for intraoperative ultrasound (US) guidance in poorly definable tumors on US.Patients MethodsIn retrospective cohort study, patients with preoperatively...
Data management in transmural care is complex. Without digital innovations like Health Information Exchange (HIE), patient information often dispersed and inaccessible across health systems between hospitals. The extent of loss consequences remain unclear. We aimed to quantify availability referred oncological patients assess its impact on unnecessary repeat diagnostics by observing all multidisciplinary team meetings (MDTs) a tertiary hospital. During 84 meetings, 165 were included....
The goal of this paper is to improve railway performances by providing more and accurate context information. A human factors engineering approach was conducted identify the appropriate Subsequently, tested in a simulation study. results indicated that train drivers change their driving decisions upon different information conditions. Moreover, they expect will decision-making performance indicators safety, punctuality, energy-costs, personnel passenger satisfaction.
Abstract BACKGROUND: Partial breast irradiation (PBI) is standard of care in low-risk cancer patients after breast-conserving surgery (BCS). Pre-operative PBI can result tumor downstaging and more precise target definition possibly resulting less treatment-related toxicity. This study aims to assess the pathologic complete response (pCR) rate one year MR-guided single-dose pre-operative patients. METHODS: The ABLATIVE-2 trial a multicenter prospective single-arm using ablative Patients ≥ 50...