- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Topic Modeling
- Lung Cancer Treatments and Mutations
- Natural Language Processing Techniques
- Text Readability and Simplification
- Pleural and Pulmonary Diseases
- Bone fractures and treatments
- COVID-19 and healthcare impacts
- Economic and Financial Impacts of Cancer
- Tracheal and airway disorders
- Advanced Radiotherapy Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Treatments and Studies
- Advances in Oncology and Radiotherapy
- Radiomics and Machine Learning in Medical Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Musculoskeletal Disorders and Rehabilitation
- Neutropenia and Cancer Infections
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Vrije Universiteit Amsterdam
2021-2024
Amsterdam University Medical Centers
2019-2024
Georgia Institute of Technology
2023
Cancer Center Amsterdam
2022-2023
Amsterdam UMC Location Vrije Universiteit Amsterdam
2018-2023
The Radiosurgery Society
2023
Dutch Cancer Society
2022
Amsterdam UMC Location University of Amsterdam
2022
University Medical Center
2022
University Hospital and Clinics
2022
<h3>Background</h3> Transthoracic minimally invasive esophagectomy (MIE) is increasingly performed as part of curative multimodality treatment. There appears to be no robust evidence on the preferred location anastomosis after transthoracic MIE. <h3>Objective</h3> To compare an intrathoracic with a cervical in randomized clinical trial. <h3>Design, Setting, and Participants</h3> This open, multicenter superiority trial was at 9 Dutch high-volume hospitals. Patients midesophageal distal...
Esophagectomy is the key component of curative esophageal cancer treatment. Textbook outcome a composite measure describing an optimal perioperative course, including variables related to radical resection, at least 15 lymph nodes, and uncomplicated postoperative course without hospital readmission. This study assessed clinicopathologic predictors textbook association with survival in 2 tertiary referral centers.All patients who underwent esophagectomy gastric tube reconstruction intent...
Training learnable metrics using modern language models has recently emerged as a promising method for the automatic evaluation of machine translation. However, existing human datasets text simplification have limited annotations that are based on unitary or outdated models, making them unsuitable this approach. To address these issues, we introduce SimpEval corpus contains: SimpEval_past, comprising 12K ratings 2.4K simplifications 24 past systems, and SimpEval_2022, challenging benchmark...
The nationwide Dutch Lung Surgery Audit (DLSA) started in 2012 to monitor and evaluate the quality of lung operations Netherlands as an improvement tool. This outline describes establishment, structure, organization audit by Society Surgeons (NVvL) Cardiothoracic (NVT), collaboration with Institute for Clinical Auditing. In addition, first 4-year results are presented.The NVvL NVT initiated a web-based registration, including weekly updated online feedback participating hospitals. Data...
To avoid delay in oncological treatment, a 6-weeks norm for time to treatment has been agreed on The Netherlands. However, the impact of COVID-19 pandemic health systems resulted reduced capacity regular surgical care. In this study, we investigated oncology Methods: A population-based analysis data derived from five audits, including patients who underwent surgery lung cancer, colorectal upper gastro-intestinal, and hepato-pancreato-biliary (HPB) malignancies, was performed. cohort 2020...
Objective: This study investigated the patterns, predictors, and survival of recurrent disease following esophageal cancer surgery. Background: Survival is usually poor, with limited prospects remission. Methods: nationwide cohort included patients distal gastroesophageal junction adenocarcinoma squamous cell carcinoma after curatively intended esophagectomy in 2007 to 2016 (follow-up until January 2020). Patients distant metastases detected during surgery were excluded. Univariable...
The COVID-19 pandemic caused disruption of regular healthcare leading to reduced hospital attendances, repurposing surgical facilities, and cancellation cancer screening programmes. This study aimed determine the impact on care in Netherlands.A nationwide was conducted collaboration with Dutch Institute for Clinical Auditing. Eight audits were expanded items regarding alterations scheduling treatment plans. Data procedures performed 2020 compared those from a historical cohort (2018-2019)....
Superior sulcus tumors (SSTs) are uncommon, and their anatomical location can make treatment challenging. We analyzed late outcomes of patients with SST treated concurrent chemoradiotherapy followed by surgical resection (trimodality) in a single tertiary institution.Patients non-small cell SSTs, who underwent trimodality therapy between 2002 2017, were selected from prospective institutional database. Patients uniformly staged 18F-fluorodeoxyglucose-positron emission tomography, computed...
Abstract Objective To evaluate the incidence, diagnostic management strategies and clinical outcomes of women with spontaneous haemoperitoneum in pregnancy (SHiP) reassess definition SHiP. Design A population‐based cohort study using Netherlands Obstetric Surveillance System (NethOSS). Setting Nationwide, Netherlands. Population All pregnant between April 2016 2018. Methods This is a case SHiP monthly registry reports NethOSS. Complete anonymised files were obtained. newly introduced online...
In patients with unresectable stage III non-small cell lung cancer, high-dose chemoradiotherapy (CRT) followed by consolidation durvalumab improves the 5-year overall survival compared to CRT alone. The feasibility and safety of salvage surgery for such who subsequently develop locoregional failure (LRF) is unclear. We evaluated our institutional experience radical-intent in this patient population.Details undergoing after were identified from an surgical database. Each patient's case...
We present an unusual case of partial anomalous venous drainage in which the vein right upper lobe drains into superior vena cava, together with azygos vein. This was discovered during surgery for a lung tumor lobe. embryological background, functional consequences and literature on this rare anatomical anomaly.
Large language models (e.g., GPT-4) are uniquely capable of producing highly rated text simplification, yet current human evaluation methods fail to provide a clear understanding systems' specific strengths and weaknesses. To address this limitation, we introduce SALSA, an edit-based annotation framework that enables holistic fine-grained simplification evaluation. We develop twenty one linguistically grounded edit types, covering the full spectrum success failure across dimensions...
Colonic interposition is an alternative for gastric conduit reconstruction after esophagectomy. Anastomotic leakage (AL) occurs in 15-25% of patients and may be attributed to reduced blood supply vascular ligation. Indocyanine green fluorescence angiography (ICG-FA) can visualize tissue perfusion. We aimed give overview the first experiences ICG-FA AL rate colonic interposition. This study included all consecutive who underwent a between January 2015 December 2021 at tertiary referral...