R.P. Groenendijk
- Cardiac, Anesthesia and Surgical Outcomes
- Esophageal Cancer Research and Treatment
- Aortic aneurysm repair treatments
- Gastric Cancer Management and Outcomes
- Aortic Disease and Treatment Approaches
- Esophageal and GI Pathology
- Nutrition and Health in Aging
- Breast Cancer Treatment Studies
- Hip and Femur Fractures
- Pregnancy and preeclampsia studies
- Appendicitis Diagnosis and Management
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- Intestinal and Peritoneal Adhesions
- Colorectal Cancer Screening and Detection
- Acute Ischemic Stroke Management
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- BRCA gene mutations in cancer
- Hemodynamic Monitoring and Therapy
- Multiple and Secondary Primary Cancers
- Abdominal vascular conditions and treatments
IJsselland Ziekenhuis
2002-2024
Dutch Institute for Clinical Auditing
2018-2021
University Medical Center Utrecht
2018-2020
Society for Vascular Surgery
2020
Haga Hospital
2020
Leiden University Medical Center
2020
Amsterdam University Medical Centers
2020
University of Amsterdam
2020
University of Groningen
2020
Radboud University Nijmegen
2000-2008
Abstract Background This study aimed to compare laparoscopic lavage and sigmoidectomy as treatment for perforated diverticulitis with purulent peritonitis during a 36 month follow-up of the LOLA trial. Methods Within arm international, multicentre LADIES trial, patients were randomised between sigmoidectomy. Outcomes collected up months. The primary outcome present was cumulative morbidity mortality. Secondary outcomes included reoperations (including stoma reversals), rates, rates in group....
This study investigated whether a supervised exercise programme improves quality of life (QoL), fatigue and cardiorespiratory fitness in patients the first year after oesophagectomy.The multicentre PERFECT trial randomly assigned to an intervention (EX) or usual care (UC) group. EX participated 12-week moderate- high-intensity aerobic resistance by physiotherapist. Primary (global QoL, QoL summary score) secondary (QoL subscales, fitness) outcomes were assessed at baseline, 12 24 weeks...
ObjectiveAge is an independent risk factor for mortality after both elective open surgical repair (OSR) and endovascular aneurysm (EVAR). As a result of ageing population, the less invasive nature EVAR, number patients over 80 years (octogenarians) being treated increasing. The morbidity following surgery are increased octogenarians. However, octogenarians who have either low or high peri-operative risks remains unclear. aim this study was to provide outcomes vs. non-octogenarians OSR EVAR...
ObjectiveThe Dutch Surgical Aneurysm Audit (DSAA) initiative was established in 2013 to monitor and improve nationwide outcomes of aortic aneurysm surgery. The objective this study examine whether surgery for intact abdominal aneurysms (iAAA) have improved over time.MethodsPatients who underwent primary repair an iAAA by standard endovascular (EVAR) or open surgical (OSR) between 2014 2019 were selected from the DSAA inclusion. outcome peri-operative mortality trend per year, stratified OSR...
Anastomotic leak (AL) is a common but severe complication after oesophagectomy. It unknown how to determine the severity of AL objectively at diagnosis. Determining may guide treatment decisions and improve future research. This study aimed identify leak-related prognostic factors for mortality, develop Severity oEsophageal Leak (SEAL) score.This international, retrospective cohort in 71 centres worldwide included patients with oesophagectomy between 2011 2019. The primary endpoint was...
Objective: This study investigated the patterns, predictors, and survival of recurrent disease following esophageal cancer surgery. Background: Survival is usually poor, with limited prospects remission. Methods: nationwide cohort included patients distal gastroesophageal junction adenocarcinoma squamous cell carcinoma after curatively intended esophagectomy in 2007 to 2016 (follow-up until January 2020). Patients distant metastases detected during surgery were excluded. Univariable...
Abstract Background This study evaluated the association of pathological tumour response (tumour regression grade, TRG) and a novel scoring system, combining both TRG nodal status (TRG-ypN score; TRG1-ypN0, TRG>1-ypN0, TRG1-ypN+ TRG>1-ypN+), with recurrence patterns survival after multimodal treatment oesophageal adenocarcinoma. Methods Dutch nationwide cohort included patients treated neoadjuvant chemoradiotherapy followed by oesophagectomy for distal or gastro-oesophageal...
Following esophagectomy, esophageal cancer patients experience a clinically relevant deterioration of health-related quality life, both on the short- and long-term. With currently growing number survivors, burden disease- treatment-related complaints symptoms becomes more relevant. This emphasizes need for interventions aimed at improving life. Beneficial effects post-operative physical exercise have been reported in several types, but so far comparable evidence is lacking. The aim this...
Abstract Background Anastomotic leak is a severe complication after oesophagectomy. has diverse clinical manifestations and the optimal treatment strategy unknown. The aim of this study was to assess efficacy strategies for different anastomotic Methods A retrospective cohort performed in 71 centres worldwide included patients with oesophagectomy (2011–2019). Different primary were compared three manifestations: interventional versus supportive-only local (that no intrathoracic collections;...
We know that screening for breast cancer leads to detection of smaller tumours with less lymph node metastases. Could it be possible the decrease in mortality after is not only caused by this earlier stage, but also a different mitotic activity index (MAI) are detected screening? Is MAI prognostic factor recurrence-free survival? A retrospective study was carried out 387 patients cancer, treated at University Hospital Nijmegen between January 1992 and September 1997. Ninety had...
Abstract Background It is questionable whether elective appendicectomy can effectively reduce persistent or recurrent right lower-quadrant abdominal pain due to chronic appendicitis. Methods This single-centre double-blind randomized clinical trial studied the effects of laparoscopic on 6 months after operation in patients with pain. A secondary outcome evaluated was relationship between response and appendiceal histopathology. The analysis performed an intention-to-treat basis. Results...
The aim of this study was to review the results and long-term outcome after total mesorectal excision (TME) for adenocarcinoma rectum in an unselected population a community teaching hospital.Between 1996 2003, 210 patients with rectal cancer were identified our prospective database, containing patient characteristics, radiotherapy plans, operation notes, histopathological reports, follow-up details. An evaluation prognostic factors local recurrence, distant metastases, overall survival...
This study evaluated the nationwide trends in care and accompanied postoperative outcomes for patients with distal esophageal gastro-esophageal junction cancer.The introduction of transthoracic esophagectomy, minimally invasive surgery, neo-adjuvant chemo(radio)therapy changed cancer.Patients after elective transhiatal esophagectomy or gastroesophageal carcinoma Netherlands between 2007-2016 were included. The primary aim was to evaluate both included patients. Additionally, tran-shiatal...
To find out which risk factors affect outcome after pneumonectomy. Retrospective study. Teaching hospital, The Netherlands. 62 patients who were treated for bronchial cancer by pneumonectomy between 1984 and 1995. Hospital mortality postoperative complications. increased with age, being 5/51 (10%) in the 40–69 age group 4/11 (36%) aged 70 or more. In American Society of Anesthesiologists (ASA) class I hospital was 8% (2/26), II 12% (3/26) III 40% (4/10). highest when FEV1:FVC-ratio below...
The sharp decrease in open surgical repair (OSR) for abdominal aortic aneurysm (AAA) has raised concerns about contemporary postoperative outcomes. study was designed to analyse the impact of complications on clinical outcomes within 30 days following OSR.Patients who underwent OSR intact AAA registered prospectively between 2016 and 2019 Dutch Surgical Aneurysm Audit were included. Complications (death, secondary interventions, prolonged hospitalization) evaluated. adjusted relative risk...