- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Biosensors and Analytical Detection
- Autoimmune and Inflammatory Disorders
- Gold and Silver Nanoparticles Synthesis and Applications
- Aerosol Filtration and Electrostatic Precipitation
- Histone Deacetylase Inhibitors Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Particle Dynamics in Fluid Flows
- CAR-T cell therapy research
- Electrohydrodynamics and Fluid Dynamics
- Plant Physiology and Cultivation Studies
- Nuclear Receptors and Signaling
- Viral Infections and Immunology Research
- Food Allergy and Anaphylaxis Research
- Parvovirus B19 Infection Studies
- Heat Transfer Mechanisms
- Electric Power System Optimization
- Solar Radiation and Photovoltaics
- Lattice Boltzmann Simulation Studies
- Fluid Dynamics and Heat Transfer
- Viral-associated cancers and disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Shandong First Medical University
2023-2025
Shandong Provincial Institute of Dermatology and Venereology
2023-2025
Academy of Medical Sciences
2025
Shandong Provincial Hospital
2023-2024
Hangzhou Hospital of Traditional Chinese Medicine
2024
Tebian Electric Apparatus (China)
2022
Second Affiliated Hospital of Zhejiang University
2021
Hangzhou Red Cross Hospital
2019
Northeastern University
2017
Nanfang Hospital
2012
To the Editor: Bullous pemphigoid (BP) is a rare autoimmune skin disorder characterized by significant mortality, with BP prevalence ranging from 1.46 to 47.99 cases per 100,000 people.[1] The pathogenic mechanism of attributed autoantibodies targeting BP180 and BP230 antigens, resulting in formation subepidermal blisters.[1] Reports indicate that some patients also have circulating anti-desmoglein (Dsg) autoantibodies, which are antibodies pemphigus.[2] However, it remains uninvestigated...
A 10-year-old boy presented with plaques and nodules accompanied by itching on his trunk extremities, persisting for 2 months. Initially, erythematous papules appeared, followed vesicles that caused pain upon rupture. He was diagnosed erythema elevatum diutinum (EED), a condition more commonly seen in adults rarely children, particularly boys. Typical clinical manifestations of EED include nodules, papules, or plaques, rare reports variants like the vesiculobullous form. While dapsone is...
<h3>Objective</h3> This study investigated the epigenetic role of PRL-3, a key metastasis gene in colorectal cancer (CRC), as regulator histone demethylation and functions Jumonji domain-containing protein 1B (JMJD1B) JMJD2B progression CRC. <h3>Methods</h3> PRL-3-associated proteins were analysed using functional distribution category enrichment analysis. Western blotting immunofluorescence used to detect nuclear PRL-3. The relationship between PRL-3 JMJD1B or roles JMJD1B, determined after...
Abstract Epidermal growth factor receptor inhibitors (EGFRIs) are widely used to treat various types of malignancies. One the common adverse reactions is cutaneous toxicity, mostly presenting as acneiform eruptions, paronychia and xerosis. Erosive pustular dermatosis scalp (EPDS) a rare reaction that develops during treatment with EGFRIs. The pathogenesis EGFRI-induced EPDS poorly understood. Here we present three cases induced by proteins LTA4H (leukotriene A-4 hydrolase), METAP1...
To facilitate rapid, efficient, and accurate detection of miR-96-5p associated with gastric cancer (GC), we developed a bioanalytical platform by integrating surface-enhanced Raman spectroscopy lateral flow assay (SERS-LFA).
Abstract Background Tuberculous pleural effusions (TBPEs) and malignant (MPEs) are two of the most common severe forms exudative effusions. Clinical differentiation is challenging; however, metabolomics a collection powerful tools currently being used to screen for disease‐specific biomarkers. Methods 17 TBPE MPE patients were enrolled according inclusion criteria. The normalization gas chromatography‐mass spectrometry (GC‐MS) data imported into SIMCA‐P + 14.1 software multivariate analysis....
Colorectal cancer (CRC) has become a significant global public health challenge, demanding immediate attention due to its high incidence and mortality rates. Regular CRC screening is essential for the early detection of precancerous lesions CRC.
The aim of the present study was to provide novel laboratory indexes for infectious mononucleosis (IM) in pediatric patients. In prospective study, a total 141 patients with IM and 146 healthy subjects were enrolled. white blood cell count (WBC), red (RBC), hemoglobin (HB), platelet (PLT), mean volume (MPV), distribution width (PDW), alanine aminotransferase (ALT), aspartate (AST), γ‑glutamyl transferase (GGT), uric acid (UA), urea, creatinine, cholesterol (TC) triglycerides (TG) peripheral...
Wind power is one of the popular renewable energy in world. And accurate wind prediction can improve quality integration and help to guarantee safety grid system. In this paper, a Rolling Auto-regressive Moving Average(RARMA) method proposed accuracy for ultra short term prediction. purpose illustrating feasibility RARMA method, numerical experiments are conducted. Simultaneously, Root Mean Square Error(RMSE), Maximum Error(MAXE), Average Relative Error(ARE), Prediction Accuracy Rate(PAR)...
OBJECTIVE To observe effects of oral intake lead on the expression Hoxa9 gen and ability learning memory explore toxic molecular mechanisms lead. METHODS Thirty male Wistar rats were chosen randomly divided into low dosage group, high group control 10 in each group. The given respectively 0.06%, 0.2% acetate orally while was distilled water orally. Y-maze test used to measure memory, graphite heat atomic absorption spectrum method determine concentration blood brain, situ hybridization (ISH)...
By building surface microstructures with coatings and simultaneously reducing energy to make them superhydrophobic, the contact time of ice or water on can be reduced, thus achieving anti-icing delayed icing effects. Existing studies have mainly investigated effect roughness superhydrophobic surfaces from a macroscopic perspective. In order study dynamic bouncing behavior microscopic mechanism droplets different microstructures, this paper adopts lattice Boltzmann method (LBM) investigate...
The deposition of particles in the heat transfer channel will cause a serious decrease efficiency. It is great significance for energy engineering and thermal application to understand characteristics particle deposition. In this study, Reynolds stress model (RSM) discrete (DPM) were used simulate three-dimensional dimple rough channel. random walk (DRW) was turbulent diffusion particles. rate analyzed by grid-independent test numerical verification. results show that turbulence structure,...