Xiaoying Lyu

ORCID: 0000-0003-0367-8848
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Oral microbiology and periodontitis research
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • MicroRNA in disease regulation
  • Anomaly Detection Techniques and Applications
  • Probiotics and Fermented Foods
  • Time Series Analysis and Forecasting
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Nephrotoxicity and Medicinal Plants
  • Microgrid Control and Optimization
  • Pickering emulsions and particle stabilization
  • Infective Endocarditis Diagnosis and Management
  • Silk-based biomaterials and applications
  • Carbon Dioxide Capture Technologies
  • Microbial Inactivation Methods
  • Advanced Computational Techniques and Applications
  • RNA modifications and cancer
  • Listeria monocytogenes in Food Safety
  • Essential Oils and Antimicrobial Activity
  • Covalent Organic Framework Applications
  • Cytomegalovirus and herpesvirus research
  • CO2 Sequestration and Geologic Interactions
  • Bee Products Chemical Analysis
  • Antibiotic Resistance in Bacteria

Huaiyin Normal University
2025

Sichuan University
2020-2024

State Key Laboratory of Oral Diseases
2020-2024

National Center of Ocean Standards and Metrology
2024

Shanghai University of Medicine and Health Sciences
2023

Sinochem Group (China)
2018-2023

Deep Ocean Technology (Poland)
2022

North China Electric Power University
2022

Huzhou Central Hospital
2019

174th hospital of the People's Liberation Army
2017

The human body's primary line of defense, the skin, is especially prone to harm. Although microRNA (miRNA)-based therapies have attracted increasing attention for skin wound healing, their applications remain limited owing a range issues. Tetrahedral framework DNA (tFNA), nanomaterial possessing nucleic acid characteristics, exhibits an excellent biocompatibility, in addition anti-inflammatory and transdermal delivery capabilities, can accelerate healing. Due its potential exert synergistic...

10.1021/acsami.4c06460 article EN ACS Applied Materials & Interfaces 2024-06-17

Macrolide pollution has attracted a great deal of attention because its ecotoxic effects on microalgae, but the role phycospheric bacteria under antibiotic stress remains unclear. This study explored toxic erythromycin (ERY) growth and nitrogen metabolism Auxenochlorella pyrenoidosa; then, it analyzed predicted composition ecological function microalgae ERY stress. We found that 0.1, 1.0, 10 mg/L inhibited chlorophyll gradually showed enhanced abilities over course 21 days. As exposure time...

10.3390/plants14010121 article EN cc-by Plants 2025-01-03

Abstract Infected wounds are a complex disease involving bacterial infections and dysregulated inflammation. However, current research has mostly focused on inhibition rather than Thus, combined therapeutic strategies with anti‐bacterial anti‐inflammation efficacies urgently needed. Antibiotics the main treatment strategy for infections. excessive use of antibiotics throughout body can cause serious side effects. In addition, miRNA‐based therapeutics superior wounds, but their rapid...

10.1002/smll.202406629 article EN Small 2024-09-16

Summary To explore the feasibility of using radio frequency ( RF ) heating as a method to process kiwi puree, this study compared effects with traditional heat pasteurisation TP on various properties puree. treatment completely inactivate microbes in total aerobic bacteria counts TAC decreased by 4.81 log CFU mL −1 and yeast mould YMC 2.62 , which are similar treatment. During 7 weeks’ storage, ‐treated puree showed retarded growth microbes. The pH titratable acidity °Brix values samples...

10.1111/ijfs.13575 article EN International Journal of Food Science & Technology 2017-09-15

Abstract MicroRNA (miRNA)‐based therapy holds significant potential; however, its structural limitations pose a challenge to the full exploitation of biomedical functionality. Framework nucleic acids are promising owing their transportability, biocompatibility, and functional editability. MiRNA‐125 is embedded into acid framework create an enzyme‐responsive nanoparachute (NP), enhancing miRNA loading capacity while preserving attributes small‐scale circumventing uncertainty related RNA...

10.1002/advs.202411210 article EN cc-by Advanced Science 2024-12-24

Dental caries is a chronic oral infectious disease caused by cariogenic biofilm adhered on the tooth surface. Our previous study demonstrated that repurposed natural compound napabucasin (NAP) showed good antimicrobial activity against streptococcal biofilms. The current designed novel small molecule, namely LCG-N25, using NAP as lead compound, and aimed to investigate its potential an agent in control of dental caries. LCG-N25 was synthesized with reference structure NAP. minimal inhibitory...

10.3389/fmicb.2021.654692 article EN cc-by Frontiers in Microbiology 2021-03-29

Abstract We describe a series of new laboratory experiments which examine the rise two‐dimensional buoyancy‐driven plume freshwater through porous layer initially saturated with aqueous saline solution. Measurements show that head accounts for constant fraction about 0.7 buoyancy supplied at source and it grows as rises layer. However, morphology becomes increasingly complex ratio injection speed to increases, fluid spreading laterally developing localized buoyant fingers intermingle ambient...

10.1002/2015gl066946 article EN cc-by-nc-nd Geophysical Research Letters 2015-12-19

Periodontitis is a chronic inflammatory disease that leads to periodontal tissue damage and tooth loss. Therefore, controlling bone loss promoting osteogenesis crucial challenge clinically. MicroRNA (miRNA) based gene therapy has shown substantial prospects in recent years, but its application been limited due structural instability easy degradation by enzymes. Research miRNA-200c regarded as key miRNA regulating multiple signaling pathways during the process of resorption. Tetrahedral...

10.1021/acsami.4c17195 article EN ACS Applied Materials & Interfaces 2024-12-16

In recent years, a large number of studies have shown that non-coding RNAs play an important role in wound healing process. Among them, on the mechanism circular RNA (circRNA) circRNA is closely related to proliferation cells healing, such as endothelial progenitor and keratinocytes, also involved chronic Based introduction concept circRNA, this paper focuses possible regulatory different stages diabetic summarizes potential process peripheral vascular atherosclerosis, aiming explore...

10.3760/cma.j.cn501225-20220727-00317 article EN PubMed 2023-05-20

Objective To explore the effect of microcolumn gel cassette method in prenatal detection immunological antibody potency pregnant women. Methods The anti-A and anti-B 180 cases O-type women (95 their partners were A type other 85 B type) detected by both card test tube anti-human globulin method, difference sensitivity between them compared. Results The mean value 46.21 33.82 respectively, former was 1.37 times higher than latter. The 47.18 35.02 1.35 To make IgG (anti-B) ≥64 to...

10.3760/cma.j.issn.1007-1245.2017.12.005 article EN 国际医药卫生导报 2017-06-15

Objective To explore the effect of horticultural therapy on rehabilitation patients with depression in hospital. Methods A total 80 cases who met inclusion criteria were selected from Third People′s Hospital Huzhou City January 2017 to December 2017. We used random-number methods classify into either intervention group or control 40 each group. While two groups both received conventional antidepressant drugs, and psychiatric care routine training. Patients also attended therapy,...

10.3760/cma.j.issn.1672-7088.2019.13.012 article EN ˜The œJournal of practical nursing 2019-05-01
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