A5012587825- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Virtual Reality Applications and Impacts
- Augmented Reality Applications
- Photoreceptor and optogenetics research
- Neurotransmitter Receptor Influence on Behavior
- COVID-19 epidemiological studies
- Advanced Memory and Neural Computing
- Cognitive and developmental aspects of mathematical skills
- Child and Animal Learning Development
- COVID-19 Pandemic Impacts
- Psychedelics and Drug Studies
- COVID-19 impact on air quality
- Biochemical Analysis and Sensing Techniques
- Single-cell and spatial transcriptomics
- Face Recognition and Perception
- Conservation Techniques and Studies
- EEG and Brain-Computer Interfaces
- Topic Modeling
- Reinforcement Learning in Robotics
- Motor Control and Adaptation
- Social Robot Interaction and HRI
- vaccines and immunoinformatics approaches
Universidade Federal do Rio Grande do Norte
2014-2023
Instituto Federal do Rio Grande do Norte
2023
Heriot-Watt University
2022
Universitat Pompeu Fabra
2009-2014
The notion of attractor networks is the leading hypothesis for how associative memories are stored and recalled. A defining anatomical feature such excitatory recurrent connections. These "attract" firing pattern network to a pattern, even when external input incomplete (pattern completion). CA3 region hippocampus has been postulated be an network; however, experimental evidence ambiguous, suggestion that not network. In order resolve this controversy better understand functions, we...
Sleep is critical for hippocampus-dependent memory consolidation. However, the underlying mechanisms of synaptic plasticity are poorly understood. The central controversy on whether long-term potentiation (LTP) takes a role during sleep and which would be its specific effect memory. To address this question, we used immunohistochemistry to measure phosphorylation Ca2+/calmodulin-dependent protein kinase II (pCaMKIIα) in rat hippocampus immediately after sleep-wake states were interrupted....
Place cells in the hippocampus and grid medial entorhinal cortex have different codes for space. However, how one code relates to other is ill understood. Based on anatomy of entorhinal-hippocampal circuitry, we constructed a model place organized loop investigate their mutual influence establishment Using computer simulations, first replicated experiments rats that measured cell activity environments, then assessed which features account phenomena observed neurophysiological data, such as...
I present a double-elimination format for the 48-team FIFA World Cup that solves many of concerns raised about considered formats with mixed round-robin groups 3 or 4 teams and single-elimination strategies. Using quantitative analytics approach, show is fairer, more strategy-proof, produces competitive exciting matches. It problems possible collusion in group-of-3 form high number uninteresting games group-of-4 format. restrictions 2026 to be held North America, demonstrate can implemented...
Museums featuring dinosaur fossils have always attracted the attention of crowd. However, sustaining public interest in science becomes more challenging year after year, even for popular attractions, calling changes how exhibits appear face new technologies. To enrich user’s experience and enhance exhibition’s attractiveness, we developed evaluated an immersive interactive Virtual Reality (VR) to integrate Paleontology exhibition at Câmara Cascudo Museum Natal, Brazil. Experienced VR users...
Abstract Throughout the brain, reciprocally connected excitatory and inhibitory neurons interact to produce gamma‐frequency oscillations. The emergent gamma rhythm synchronizes local neural activity helps select which cells should fire in each cycle. We previously found that such excitation‐inhibition microcircuits, however, have a potentially significant caveat: frequency of oscillation level selection (i.e., percentage are allowed fire) vary with magnitude input signal. In networks varying...
Abstract Psychedelic agonists of serotonin receptors induce neural plasticity and synaptogenesis, but their potential to enhance learning remains uncharted. Here we show that a single dose d-LSD, potent serotonergic agonist, increased novel object preference in young adult rats several days after treatment. d-LSD alone did not increase old animals, could rescue it levels when followed by 6-day exposure enriched environment (EE). Mass spectrometry-based proteomics human brain organoids...
The hippocampal formation displays a wide range of physiological responses to different spatial manipulations the environment. However, very few attempts have been made identify core computational principles underlying those responses. Here, we capitalize on observation that entorhinal-hippocampal complex (EHC) forms closed loop and projects inhibitory signals "countercurrent" trisynaptic pathway build self-supervised model learns reconstruct its own inputs by error backpropagation. EHC is...
In the global effort to discover biomarkers for cancer prognosis, prediction tools have become essential resources. TCR (T cell receptor) repertoires contain important features that differentiate healthy controls from patients or outcomes being treated with different drugs. Considering, can easily and quickly generate identify out of repertoire data build accurate classifiers predict future are essential.This paper introduces GENTLE (GENerator T receptor machine LEarning): an open-source,...
Finger-based representation of numbers is a high-level cognitive strategy to assist numerical and arithmetic processing in children adults. It unclear whether this paradigm builds on simple perceptual features or comprises several attributes through embodiment. Here we describe the development initial testing an experimental setup study embodiment during finger-based task using Virtual Reality (VR) low-cost tactile stimulator that easy build. Using VR allows us create new ways virtual hand...
The connectivity of the cerebral cortex is characterized by dense local and sparse long-range connectivity. It has been proposed that this connection topology provides a rapid robust transformation spatial stimulus information into temporal population code (TPC). TPC canonical model cortical computation whose topological requirements are independent properties input stimuli and, therefore, can be generalized to processing all areas. Here we propose real time implementation for classifying...
It has been proposed that the dense excitatory local connectivity of neo-cortex plays a specific role in transformation spatial stimulus information into temporal representation or population code (TPC). TPC provides for rapid, robust, and high-capacity encoding salient features with respect to position, rotation, distortion. The hypothesis gives functional interpretation core feature cortical anatomy: its sparse long-range connectivity. Thus far, question how can be decoded downstream areas...
Foraging can be described as goal-oriented exploration for resources. It exemplifies how animals coordinate complex sensory and effector systems under varying environmental conditions. To emulate the foraging capabilities of natural is a major goal robotics. Therefore, an excellent paradigm to benchmark novel autonomous control strategies. Here we describe biomimetic architecture Synthetic Forager (SF), effort integrate multiple biologically constrained models specific perceptual cognitive...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic hit almost all cities in Brazil early 2020 and lasted for several months. Despite the effort of local state municipal governments, an inhomogeneous nationwide response resulted a death toll amongst highest recorded globally. To evaluate impact nonpharmaceutical governmental interventions applied by different cities-such as closure schools businesses general-in evolution epidemic spread SARS-CoV-2, we constructed...
Museums are plural spaces that can exhibit different forms of art, cultural pieces, as well educational content. In this environment, virtual reality (VR) is being used a tool to enhance those and create new experiences were not possible before. This paper describes the process creating such an experience by reporting on conceptual development, technical deployment, evaluation MedusoZoa, immersive interactive VR system was installed in Câmara Cascudo Museum part museum week. The...
Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully understood. Recent advancements in Large Language Model (LLM) architectures have developed many tools to identify representative features neurological spontaneous speech. However, LLMs typically lack interpretability, meaning they do provide clear specific reasons...
Multimodal performances aggregate multiple forms of interaction and stimulation to create artistical masterpieces. One those is the Ode Christus Hypercubus, by Jônatas Manzolli. To enhance original version this performance add new layers interaction, an Augmented Reality (AR) experience was developed. This paper describes development application, all artistic concepts that were part development, technologies used final experience. Finally, a live using AR interface in real setting during...