A5072390164- Renal Diseases and Glomerulopathies
- Attention Deficit Hyperactivity Disorder
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Smoking Behavior and Cessation
- Obesity, Physical Activity, Diet
- Musculoskeletal pain and rehabilitation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Stroke Rehabilitation and Recovery
- Cancer survivorship and care
- Diabetes Management and Research
- Pediatric Pain Management Techniques
- Pregnancy and Medication Impact
- Vascular Procedures and Complications
- Autism Spectrum Disorder Research
- Infant Development and Preterm Care
- Child and Adolescent Psychosocial and Emotional Development
- Asthma and respiratory diseases
- Breast Cancer Treatment Studies
- Cytomegalovirus and herpesvirus research
- Diabetes Treatment and Management
- Allergic Rhinitis and Sensitization
- Multiple and Secondary Primary Cancers
Skaraborg Hospital
2015-2024
University of Gothenburg
2021-2024
Region Västra Götaland
2023-2024
Umeå University
2002-2020
FoU Södertörn
2020
Centre for Research and Development
2017
Incidence, manifestations and case-fatality rate (CFR) of invasive pneumococcal disease (IPD) vary with age comorbidities. New vaccines, changing distribution, prolonged survival among immunocompromised patients improved sepsis management have created a need for an update basic facts to inform vaccine recommendations.Age, gender comorbidities were related death 2977 consecutive IPD in Swedish region 1.5 million inhabitants during 13 years before introduction conjugate vaccines (PCV) the...
Abstract. Rodu B, Stegmayr Nasic S, Asplund K (University of Alabama at Birmingham, AL, USA and University Hospital, Umeå, Sweden). Impact smokeless tobacco use on smoking in northern Sweden. J Intern Med 2002; 252: 398–404. Background objectives. For many years Swedish men have had the world's lowest rates smoking‐related mortality. Despite these facts, a thorough analysis patterns Sweden has not been performed. The purpose this study was to examine prevalence interaction cigarette moist...
Abstract. Objective. To explore the effect of smoking and smokeless tobacco, ‘snus’, on risk type 2 diabetes. Design. Population‐based cross‐sectional prospective follow‐up study in northern Sweden. Subjects. A total 3384 men, aged 25–74 years, who participated MONICA 1986, 1990, 1994 or 1999, 1170 whom had an oral glucose tolerance test. In 1757 men from previous cohorts returned for re‐examination. Main outcome measures. We compared prevalence diabetes pathological (PGT) amongst tobacco...
The primary objective of this study was to investigate if extended antibiotic treatment against bacterial vaginosis (BV) together with adjuvant lactobacilli could cure BV and, furthermore, factors that cause relapse. In all, 63 consecutive women diagnosed by Amsel criteria were offered a much more aggressive than used in normal clinical practice repeated clindamycin and metronidazole vaginal gelatine capsules containing different strains both newly characterised commercial one (109...
Cytomegalovirus (CMV) is associated with an increased risk of cardiac allograft vasculopathy (CAV), the major limiting factor for long-term survival after heart transplantation (HTx). The purpose this study was to evaluate impact CMV infection during follow-up HTx. A retrospective, single-centre analyzed 226 HTx recipients (mean age 45 ± 13 years, 78 % men) who underwent between January 1988 and December 2000. incidence factors first year were studied. Risk CAV included in analyses CAV-free...
Snuff and other forms of smokeless tobacco are widely used in some populations. Whereas the detrimental cardiovascular effects smoking well documented, possible health hazards associated with use remain controversial. The purpose this study was to explore whether snuff, a product, increases risk stroke men.In nested case-control (1 case 2 matched controls without disease), information on habits collected through population factor surveys. During follow-up, first-ever fatal nonfatal strokes...
In Brief PURPOSE This randomized controlled study aimed to evaluate the effects on psychosocial variables of a 1-year group-based cognitive-behavioral stress management program developed specifically for women with ischemic heart disease. METHODS The present explanatory (per protocol) analyses include 80 who were and 86 usual care (age = 35–77 years). Data obtained before randomization after 1 year, when intervention group had completed program. RESULTS There no statistically significant...
Background: Knowledge about the prevalence of obstructive sleep apnea (OSA) in coronary artery disease (CAD) is insufficient. The aim current report was to evaluate occurrence and predictors OSA among revascularized patients with CAD within framework a randomized controlled trial (Randomized Intervention CPAP Coronary Artery Disease Sleep Apnea [RICCADSA]), evaluating impact continuous positive airway pressure on cardiovascular outcomes OSA.Material Methods: All undergoing percutaneous...
Data on the long-term time course of poststroke functional outcome is limited. We investigated changes in over 5 years after stroke a hospital based cohort.Consecutive patients who were independent activities daily living (ADL) and admitted to Stroke Unit at Skaraborg Hospital, Sweden for first acute from 2007 2009 (n = 1,421) followed-up 3 months thereafter annually using postal questionnaire. Clinical variables post obtained Swedish Register. ADL dependency was defined as dependence...
Abstract. Rodu B, Stegmayr Nasic S, Cole P, Asplund K (University of Alabama at Birmingham, AL, USA; Umeå Hospital, Umeå, Sweden). Evolving patterns tobacco use in northern Sweden. J Intern Med 2003; 253: 660–665. Background and objectives. Cross‐sectional data from Sweden suggest that the increased Swedish moist snuff (snus) may have contributed to a decline prevalence smoking, especially amongst men. This study describes evolving this population over period 1986–1999. Design. is...
Summary Aim: To evaluate the efficacy of ‘the perioperative dialogue (PD)’ by analyzing salivary cortisol, in 5‐ to 11‐year‐old children undergoing day surgery. Background: deal with anxiety prior investigations and/or procedures, need be confident and informed about what is going happen. Therefore, intervention strategies should initiated before admission hospital. Methods materials: Children ( n = 93), 79 boys 14 girls, scheduled for elective surgery requiring general anesthesia were...
Cytomegalovirus (CMV) is the most common opportunistic infection following lung transplantation. CMV replication in allograft described as accelerating development of bronchiolitis obliterans syndrome (BOS). Finding a strategy to prevent an important issue. We performed retrospective, single-centre study 114 transplant recipients (LTRs) who underwent transplantation from January 2001 December 2006. In smaller cohort 88 seropositive (R+) LTRs, three months valganciclovir prophylaxis...
Abstract Aim To evaluate whether the administration of desmopressin alters risk for renal biopsy complications. Methods A multicenter registry containing 576 native kidney biopsies (NKb) with a serum creatinine above 150 μmol/L in 527 patients (372 men and 155 women, median age 61 years) was used. Most data were prospective. At one hospitals all received before (NKb 204). These compared to outcome complications against other centres where not given 372). Fisher's exact test, χ 2 analyses,...
Introduction Obesity is a rapidly growing global health concern with considerable negative impact on life-time expectancy. It has yet not been clarified if and how obesity impacts outcomes of severe bacterial infections. The aim this study was to determine body mass index outcome infections in well-defined population-based cohort. Methods This based cohort 2196 patients included Swedish prospective, population-based, consecutive observational the incidence community-onset sepsis septic shock...
Cognitive impairments, including spatial memory and learning deficiencies, are common after ischemic stroke. Estrogen substitution improves cognitive functions in post-menopausal women ovariectomized rodents, partially through induction of neuroplasticity the hippocampal formation. Post-ischemic housing male rats an enriched environment (EE) functional outcome, without changing infarct volume. We hypothesized that 17beta-estradiol combined with EE would accelerate recovery focal brain...
Immunoglobulin A nephropathy (IgAN) frequently leads to kidney failure. The urinary proteomics-based classifier IgAN237 may predict disease progression at the time of biopsy. We studied whether also predicts later in course IgAN.Urine from patients with biopsy-proven IgAN was analyzed using capillary electrophoresis-mass spectrometry baseline (IgAN237-1, n = 103) and follow-up (IgAN237-2, 89). Patients were categorized as "non-progressors" (IgAN237 ≤0.38) "progressors" >0.38). Estimated...
Abstract. Objective. To explore the effect of tobacco use (smoking and smokeless tobacco) cessation on body weight. Design. Cross‐sectional prospective follow‐up study. Setting. Northern Sweden. Subjects. A total 2993 men aged 25–64 years who participated in northern Sweden MONICA study 1986, 1990 or 1994, 1650 whom were followed up 1999. Main outcome measures. The prevalence overweight [body mass index (BMI) ≥ 27] amongst users was compared with nonusers at entry into average annual...
Abstract. Background: The aim of this study was to compare time trends in incidence, case fatality and mortality due myocardial infarction (MI) patients with or without diabetes. Methods: This based on the Northern Sweden MONICA Project MI registry a target population about 200 000 inhabitants age group 35–64 years two northernmost counties Sweden. During 1989–2000, 6254 who had an according criteria were included study: 4569 first 1685 recurrent MI. Sixteen per cent men 20% women diabetes...