A5101738240- Medical Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Nanoplatforms for cancer theranostics
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Cancer-related molecular mechanisms research
- Hormonal and reproductive studies
- Lung Cancer Diagnosis and Treatment
- Platelet Disorders and Treatments
- Ecosystem dynamics and resilience
- Pharmacological Effects of Natural Compounds
- Bladder and Urothelial Cancer Treatments
- Sperm and Testicular Function
- Ecology and Vegetation Dynamics Studies
- Mycobacterium research and diagnosis
- Educational Reforms and Innovations
- Neurological Disorders and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Photodynamic Therapy Research Studies
- Traditional Chinese Medicine Analysis
- Neuroscience and Neuropharmacology Research
- Plant Parasitism and Resistance
- Neurological Disease Mechanisms and Treatments
- Urinary and Genital Oncology Studies
Jiangxi University of Traditional Chinese Medicine
2025
Zhejiang University
2012-2024
Zhejiang Chinese Medical University
2013-2024
Sir Run Run Shaw Hospital
2013-2024
Shanghai University
2024
Foshan University
2024
Shijiazhuang Tiedao University
2024
Zhongda Hospital Southeast University
2022-2023
China Jiliang University
2022
Nanjing General Hospital of Nanjing Military Command
2018-2020
Combination therapy with high efficacy and precision shows great potential in breast cancer treatment. Herein, we developed a multifunctional nanocarrier (NBP@mSiO2-PEG-cRGD) for tumor-targeting chemo-photothermal of controlled manner. The was constructed by enveloping nano-sized black phosphorus (NBP) within mesoporous silica shell (mSiO2) modified the peptide c(Arg-Gly-Asp-dPhe-Cys) (cRGD). Due to existence pore channels mSiO2, NBP@mSiO2-PEG-cRGD achieved loading efficiency...
The size effect of mesoporous organosilica nanoparticles (MONs) on tumor penetration and accumulation remains poorly understood, which strongly affects the therapeutic efficacy.
Background Compared to alternative weight-loss strategies and medications, semaglutide stands out for its convenience efficacy, resulting in a significant increase prescriptions raising public safety concerns. Furthermore, the profiles of oral subcutaneous formulations require further examination. Objective Our goal is investigate potential risks associated with by analyzing data from FAERS database social media. Additionally, we aim compare adverse drug reaction (ADR) signals between...
The stress gradient hypothesis (SGH) predicts that the importance or intensity of competition and facilitation will change inversely along abiotic gradients. It was originally postulated increasing environmental can induce a monotonic increase in facilitation. However, more recent models predicted relationship between severity interaction exhibits hump‐shaped pattern, which positive interactions prevail under moderate but decline at extreme ends In present study, we conducted field...
Real-time monitoring of oxygen consumption is beneficial to predict treatment responses and optimize therapeutic protocols for photodynamic therapy (PDT). In this work, we first demonstrate that deformable hollow mesoporous organosilica nanoparticles (HMONs) can be used load [(Ru(dpp)3)]Cl2 detecting (denoted as HMON-[(Ru(dpp)3)]Cl2). This nanoprobe shows significantly improved biocompatibility high cellular uptake. In-vitro experiments the HMON-[(Ru(dpp)3)]Cl2 sensitively detect changes...
Abstract In the present study, we examined therapeutic effects of pentacyclic triterpenes, oleanolic acid (OA) and maslinic (MA), on hyperlipidemia in a high‐cholesterol diet model. Hyperlipidemia was induced male Sprague‐Dawley rats by feeding with (HCD) for 30 days. MA OA were supplemented (100 mg/kg body wt/day) during last 15 The levels serum total cholesterol (TC), triglyceride (TG), high‐density lipoprotein‐cholesterol (HDL‐C), low‐density (LDL‐C) increased hyperlipidemic rats. An...
ATP-binding cassette A3 (ABCA3) is a phospholipid carrier that mainly expressed in the alveolar epithelium. Biallelic mutations of ABCA3 has been associated with fatal respiratory distress syndrome and interstitial lung disease (ILD) children. However, whether variations have role development adult ILD, including idiopathic pulmonary fibrosis (IPF), remains to be addressed. In this study, we screened for germline variants by exons-sequencing 30 patients sporadic IPF matched healthy controls....
Although it is believed that carnosine has protective effects on various cell types, its effect microvascular endothelial cells not been well defined. In the present study, we investigated of in using an vitro rotenone-induced oxidative stress model. Mouse brain were exposed to 1 μmol/L rotenone for 18 h. some experiments, (100 nmol/L-1 mmol/L) was added 30 min prior exposure. When used, histamine receptor antagonists nmol/L-10 μmol/L) 15 before treatment. After exposure, apoptosis analysed...
The use of artificial intelligence (AI) assisted white light imaging (WLI) detection systems for superficial esophageal squamous cell carcinoma (SESCC) is limited by training with images from one specific endoscopy platform.In this study, we developed an AI system a convolutional neural network (CNN) model using WLI Olympus and Fujifilm platforms. dataset consisted 5892 1283 patients, the validation included 4529 1224 patients. We assessed diagnostic performance compared it that...
Titanium (Ti) is generally considered as an ideal bipolar plate (BPP) material because of its excellent corrosion resistance, good machinability and lightweight nature. However, the easy-passivation property, which leads to increased interfacial contact resistance (ICR) subsequently decreased cell performance, limits large-scale commercial application in proton exchange membrane fuel cells (PEMFCs). In this paper, we proposed a NiTi alloy prepared by suction casting promising for PEMFCs....
Abstract Background Manual cytological diagnosis for early esophageal squamous cell carcinoma (early ESCC) and high‐grade intraepithelial neoplasia (HGIN) is unsatisfactory. Herein, we have introduced an artificial intelligence (AI)‐assisted such lesions. Methods Low‐grade lesion or worse was set as the diagnostic threshold AI‐assisted diagnosis. The performance of evaluated compared to that manual Feasibility in large‐scale screening also assessed. Results abnormal cells superior reading by...
Subtle genetic variants in ion-channel genes might be at the origin of less rare forms hypertension general population. To test this hypothesis, we observed role several important polymorphisms (T1155547C exon7, G1155942T exon8, G1156666A intron10, and C1163527T intron14) WNK4 (with-no-kinase) gene on prevalence essential a Chinese minority ethnic group—the Uyghur We did not find significantly different distribution genotype allele frequency T1155547C, G1155942T, between hypertensives...
Real-time simulation of ring-grid laser images using the conventional method has several drawbacks, including weak edge fitting, poor clarity, low image recognition rates, uneven brightness distribution, and significant interference from surrounding environment. In this research, we develop diagonalizable readily invertible Hessian matrix, offer an enhanced Newton projection iteration algorithm, use degenerate gradient magnitude as constraint set. We also a real-time re-illumination model...