A5048866505- Advanced Radiotherapy Techniques
- Brain Metastases and Treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Effects of Radiation Exposure
- Radiomics and Machine Learning in Medical Imaging
- Testicular diseases and treatments
- Cutaneous Melanoma Detection and Management
- PARP inhibition in cancer therapy
- Sarcoma Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Head and Neck Cancer Studies
- Colorectal and Anal Carcinomas
- Melanoma and MAPK Pathways
- Cardiac tumors and thrombi
- Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Retinal Development and Disorders
- Breast Cancer Treatment Studies
- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Tumors and Oncological Cases
- Breast Implant and Reconstruction
University of Colorado Anschutz Medical Campus
2014-2025
University of Colorado Denver
2014-2025
University of Colorado Cancer Center
2023-2024
University of Colorado Colorado Springs
2017-2021
The Medical Center of Aurora
2016
The Netherlands Cancer Institute
2016
The University of Texas Medical Branch at Galveston
2015
Beaumont Health
2015
Emory University
2008-2013
<h3>Importance</h3> Data on adjuvant concurrent chemoradiotherapy (CRT) after resection of salivary gland carcinomas (SGCs) are limited. <h3>Objective</h3> To examine overall survival (OS) outcomes patients who receive CRT vs radiotherapy (RT) alone SGCs. <h3>Design, Setting, and Participants</h3> The National Cancer Base (NCDB), a hospital-based registry that represents 70% all cancer cases in the United States, was queried for underwent major SGCs with at least 1 high-risk feature (T3-T4...
Abstract Five-year survival for human papilloma virus-unrelated head and neck squamous cell carcinomas remain below 50%. We assessed the safety of administering combination hypofractionated stereotactic body radiation therapy with single-dose durvalumab (anti-PD-L1) neoadjuvantly ( n = 21) NCT03635164 ). The primary endpoint study was safety, which met. Secondary endpoints included radiographic, pathologic objective response; locoregional control; progression-free survival; overall survival....
Because interphotoreceptor retinoid-binding protein (IRBP) is expressed before being needed in its presumptive role the visual cycle, we tested whether it controls eye growth during development.The eyes of congenic IRBP knockout (KO) and C57BL/6J wild-type (WT) mice ranging age from postnatal day (P)2 to P440 were compared by histology, laser micrometry, cycloplegic photorefractions, partial coherence interferometry.The size weight KO mouse greater than those WT mouse, even eye-opening....
466 Background: Recent data support use of perioperative FLOT (5-FU/leucovorin/oxaliplatin/docetaxel) chemotherapy over pre-operative chemoradiation (CRT) for patients with resectable esophageal/GEJ adenocarcinoma limited studies evaluating combined FLOT/CRT. This prospective phase II study (NCT04028167) evaluated a neoadjuvant approach followed by CRT (EAC). Methods: Operable cT1-2 N1-2 or cT3-4N any4 Nany non-metastatic EAC were eligible. Neoadjuvant treatment consisted x 3 cycles...
4DCT-ventilation is an exciting new imaging modality that uses 4DCT data to calculate lung-function maps. Because 4DCTs are acquired as standard of care for lung cancer patients undergoing radiotherapy, 4DCT-ventiltation provides functional information at no extra dosimetric or monetary cost the patient. The development clinical trials underway use spare in radiotherapy. purpose this work was perform a virtual trial using retrospective develop practical aspects avoidance trial.The study...
Sex differences in cancer are well-established. However, less is known about sex diagnosis of brain metastasis and outcomes among patients with advanced melanoma. Using a United States nationwide electronic health record-derived de-identified database, we evaluated diagnosed melanoma from 1 January 2011–30 July 2022 who received an oncologist-defined rule-based first line therapy (n = 7969, 33% female according to EHR, 35% w/documentation metastases). The odds documented were calculated...
We evaluated survival outcomes between dose-escalated EBRT (external beam radiotherapy) vs plus brachytherapy for intermediate and high risk prostate cancer using NCDB (National Cancer Data Base).Patients with cN0M0 treated from 2004 to 2006 were divided into radiotherapy comparison groups, including alone (75.6 81 Gy) (40 50.4 delivered at 1.8 2.0 Gy per fraction. Brachytherapy data limited yes/no no information on modality, dose or schedule. Eligible patients known have received androgen...
Purpose: 4DCT‐ventilation is an exciting new imaging modality that uses 4DCTs to calculate lung ventilation. Because are acquired as part of routine care, calculating allows for function evaluation without additional cost or inconvenience the patient. Development a clinical trial underway at our institution use thoracic functional avoidance with idea preferential sparing regions can decrease pulmonary toxicity. The purpose work was develop practical aspects including: 1.assessing patient...
Abstract To characterize radiation necrosis following hypofractionated brainstem re‐irradiation in pediatric patients, we reviewed 23 cases with 28 tumors invading or abutting and treated from 2004 to 2014. Re‐irradiation delivered total doses of 16–30 Gy two five fractions. The most commons regimens used were 24 three fractions 25 At median follow‐up 12.8 months, overall survival was 14.7 months eight in‐field recurrences detected (median time 10.5 months). Five patients experienced...
The purpose of this report is to present the implementation a process for after-hours radiation treatment (RT) utilizing remote planning based on optimized diagnostic computed tomography (CT) scans urgent palliative inpatients. A standardized operating procedure was developed by an interprofessional panel improve quality RT and minimize risk errors. new CT protocol created that could be performed hospital scanners would ensure reproducible patient position adequate field view. An on-call...