A5083061118- Boron and Carbon Nanomaterials Research
- Nuclear Materials and Properties
- Silicon Carbide Semiconductor Technologies
- Fusion materials and technologies
- Nuclear Physics and Applications
- Nuclear reactor physics and engineering
- Atomic and Subatomic Physics Research
- Hydrogen Storage and Materials
- MXene and MAX Phase Materials
- Advanced ceramic materials synthesis
- Intermetallics and Advanced Alloy Properties
- Microstructure and mechanical properties
- Superconductivity in MgB2 and Alloys
- Copper Interconnects and Reliability
- Ion-surface interactions and analysis
- Circadian rhythm and melatonin
- Semiconductor materials and devices
- Thermal Expansion and Ionic Conductivity
- Inflammasome and immune disorders
- Metal and Thin Film Mechanics
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Chromatin Remodeling and Cancer
- Nuclear materials and radiation effects
- Heme Oxygenase-1 and Carbon Monoxide
Tianjin Chest Hospital
2020-2024
Tianjin University
2023-2024
China Academy of Engineering Physics
2005-2023
Tianjin Medical University
2021
Mianyang Normal University
2019
Peking University
2018
Atherosclerosis (AS), a significant contributor to cardiovascular disease (CVD), is steadily rising with the aging of global population. Pyroptosis and apoptosis, both caspase-mediated cell death mechanisms, play an essential role in occurrence progression AS. The human pineal gland primarily produces melatonin (MT), indoleamine hormone powerful anti-oxidative, anti-pyroptotic, anti-apoptotic properties. This study examined MT's anti-oxidative stress anti-pyroptotic effects on THP-1...
Abstract Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mechanism remains elusive. Here, mice were fed high-fat diet (HFD) supplemented L-NAME for 12 weeks and subsequently intraperitoneally injected EMPA another 4 weeks. A 4D-DIA proteomic assay was performed to detect protein changes failing hearts. We identified 310 differentially...
Oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell dysfunction is a significant event in the progression of atherosclerosis. Even Myricetin (Myr) has been exhibited strong antioxidant potency, effect on atherosclerosis still elusive. HUVECs were subjected to ox-LDL, before which cells preconditioned with Myr. Cell Counting Kit-8 assay, flow cytometry, quantitative real-time polymerase chain reaction and Western blot carried out assess impacts ox-LDL Myr HUVECs. The expression...
(A) Outline of the synthesis CMCS-S-S-Py and (B) schematic depiction fabrication CMCS/BSA hydrogel its properties.
The elastic and thermodynamic properties of tetragonal Be12Ti under high temperature pressure are investigated by first-principles calculations based on pseudopotential plane-wave density functional theory (DFT) within the generalized gradient approximation (GGA) quasi-harmonic (QHA). calculated lattice parameters bulk modulus in good agreement with available experimental data. constants increase monotonously increasing pressure, stability criterion phonon dispersion calculation show that...
Understanding the mechanical properties of structural materials under an irradiation environment stands as a major challenge for developing advanced nuclear systems. In this paper, properties, including Young's modulus, yield stress, and hardness, SiC samples irradiated by neutron heavy ions (3 MeV C Si ions) have been investigated nanoindentation measurement. When load-depth curves were analyzed widely used Oliver-Pharr method, at same displacement damage level (0.1 0.2 dpa), both elastic...
The structural, elastic, and thermodynamic properties of cubic-Fe2TiAl under high temperatures pressures are investigated by performing ab initio calculation using the quasi-harmonic Debye model. Some ground state such as lattice constant, bulk modulus, pressure derivative elastic constants in good agreement with available experimental results theoretical data. Fe2TiAl thermal expansion coefficient, temperature, heat capacity ranges 0 K—1200 K GPa—250 GPa also obtained. indicate that...
The geometry structure, electronic total energy, Mulliken changes of He atom in the Al octahedral site and tetrahedral were studied by first-principle plane-wave pseudopotential method GGA. calculation results indicated that crystal lattice was changed when enter to interstitial Al, but are change smaller than site. For system, impurity formation energies helium 1.3367 2.4411 eV site, respectively. It is found for best stable state Al. At same time, occupancy its effect cell analysis this...
To compare the hemodynamic and clinical outcomes following mitral valve replacement with Perimount those of Mosaic valve.A total 145 consecutive patients rheumatic heart disease who underwent single bioprosthetic were randomized to receive either (n=72) or bioprosthesis (n=73). The mean age was 72.1 years (range, 58-89 years) a sex distribution 55.2% female 44.8% male. Patients follow up transthoracic echocardiography at 3 months 1 year postoperatively. We compared demographics, preoperative...
NbH2 hydride is an important material in hydrogen storage materials. However, until now there have been no experimental and theoretical data on the elastic thermodynamic properties. The structure properties of cubic-NbH2 under high temperatures pressure are investigated by first-principles study based pseudo-potential plane-wave density functional theory method using generalized gradient approximation quasi-harmonic Debye model. results show that calculated structural parameters good...
First-principles calculations with the advanced SCAN functional were carried out to investigate defect formation energies and migration barriers of specific neutral point defects in 6H-SiC including monovacancy, antisite, self-interstitial defects, as well lattice swelling effect caused by them. Our calculation results show that CSi antisite is easiest formed C-rich environment SiC has lowest energy Si-rich environment, while ISi interstitial most difficult be generated both cases compared...
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Postoperative Atrial Fibrillation (POAF) frequently follows Coronary Artery Bypass Grafting (CABG) surgery. This prospective study investigates genes linked to POAF in CABG patients, aiming create a predictive model. Employing differential gene and methylation analyses, the identified four (WARS2, CKAP2, CHI3L1, HSD17B6) associated with POAF. Preoperative plasma samples clinical data were collected from 139 categorized into (+) (43) (-) (96). Real-time quantitative PCR assessed expression,...