A5040986961- COVID-19 Clinical Research Studies
- Cancer-related molecular mechanisms research
- Long-Term Effects of COVID-19
- Multiple Myeloma Research and Treatments
- Circular RNAs in diseases
- Immune cells in cancer
- Oral microbiology and periodontitis research
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Bone Metabolism and Diseases
- Advanced SAR Imaging Techniques
- Inflammasome and immune disorders
- Plant Reproductive Biology
- Redox biology and oxidative stress
- Systemic Lupus Erythematosus Research
- Heat shock proteins research
- Polyamine Metabolism and Applications
- Reproductive System and Pregnancy
- Glutathione Transferases and Polymorphisms
- Lipoproteins and Cardiovascular Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Chemokine receptors and signaling
- Plant Pathogens and Fungal Diseases
- Optical measurement and interference techniques
- Biochemical Acid Research Studies
Henan Agricultural University
2021-2025
Yangzhou Polytechnic Institute
2025
Soochow University
2025
First Affiliated Hospital of Soochow University
2025
Duke University
2023-2024
Second Affiliated Hospital of Xinjiang Medical University
2017-2024
Xinjiang Medical University
2017-2024
Chinese Academy of Sciences
2022-2024
Aerospace Information Research Institute
2022-2024
Duke Medical Center
2022-2024
The dynamic changes of lymphocyte subsets and cytokines profiles patients with novel coronavirus disease (COVID-19) their correlation the severity remain unclear.
Abstract Data from patients with coronavirus disease 2019 (COVID-19) are essential for guiding clinical decision making, furthering the understanding of this viral disease, and diagnostic modelling. Here, we describe an open resource containing data 1,521 pneumonia (including COVID-19 pneumonia) consisting chest computed tomography (CT) images, 130 features (from a range biochemical cellular analyses blood urine samples) laboratory-confirmed severe acute respiratory syndrome 2 (SARS-CoV-2)...
Background: The dynamic changes of lymphocyte subsets and cytokines profiles patients with novel coronavirus disease (COVID-19) their correlation the severity remain unclear. Method: Peripheral blood samples were longitudinally collected from 40 confirmed COVID-19 examined for by flow cytometry cytokine specific immunoassays. Findings: Of enrolled, 13 severe cases showed significant sustained decreases in counts but increases neutrophil than 27 mild cases. Further analysis demonstrated T...
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induced Disease 2019 (COVID-19) has posed a global threat to public health. The immune system is crucial in defending and eliminating the virus infected cells. However, dysregulation may result rapid progression of COVID-19. Here, we evaluated subsets, phenotypic functional characteristics natural killer (NK) T cells patients with COVID-19 their associations disease severity. Methods: Demographic clinical data enrolled...
Abstract Background The dynamic changes of lymphocyte subsets and cytokines profiles patients with novel coronavirus disease (COVID-19) their correlation the severity remain unclear. Methods Peripheral blood samples were longitudinally collected from 40 confirmed COVID-19 examined for by flow cytometry cytokine specific immunoassays. Results Of enrolled, 13 severe cases showed significant sustained decreases in counts but increases neutrophil than 27 mild cases. Further analysis demonstrated...
Studying placental functions is crucial for understanding pregnancy complications. However, imaging placenta challenging due to its depth, volume, and motion distortions. In this study, we have developed an implantable window in mice that enables high-resolution photoacoustic fluorescence of development throughout the pregnancy. The exhibits excellent transparency light sound. By combining with ultrafast functional microscopy, were able investigate during entire mouse pregnancy, providing...
Nephritis is one of the major complications systemic lupus erythematosus. While glucocorticoids (GCs) are frequently used as first-line treatment for nephritis (LN), long-term GC usage often complicated by severe adverse effects. To address this challenge, we have developed a polyethylene glycol-based macromolecular prodrug (ZSJ-0228) dexamethasone, which self-assembles into micelles in aqueous media. When compared to dose equivalent daily dexamethasone 21-phosphate disodium (Dex) treatment,...
Abstract The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) was initially reported in Wuhan, China since December, 2019. Here, we a timely and comprehensive resource named iCTCF to archive 256,356 chest computed tomography (CT) images, 127 types clinical features (CFs), laboratory-confirmed SARS-CoV-2 status from 1170 patients, reaching data volume 38.2 GB. To facilitate COVID-19 diagnosis, integrated the heterogeneous CT CF...
Cognitive impairment is a common, yet often overlooked, complication in thyroid cancer patients, potentially influenced by various demographic, clinical, biochemical, and psychological factors. This study aims to analyze the prevalence determinants of cancer-related cognitive (CRCI) patients. A retrospective case-control was conducted involving 246 patients treated at our The First Affiliated Hospital Soochow University from January 2021 2023. Patients were categorized into high function (n...
Recent advances in recommender systems have shown that user-system interaction essentially formulates long-term optimization problems, and online reinforcement learning can be adopted to improve recommendation performance. The general solution framework incorporates a value function estimates the user's expected cumulative rewards future guides training of policy. To avoid local maxima, policy may explore potential high-quality actions during inference increase chance finding better rewards....
: Advanced oxidation processes (AOPs) are recognized as one of the most effective methods in field wastewater treatment, and selection catalysts process is very important. In face traditional test trial-and-error method, method screening advanced time-consuming inefficient. This paper examines approximately two decades’ worth literature pertaining to development facilitated by machine learning. A synopsis various reactive oxygen species (ROS) provided. Subsequently, it posited that swift...
β-arrestin 2 (ARRB2) is involved in the desensitization and trafficking of G protein-coupled receptors (GPCRs) plays a critical role cell proliferation, apoptosis, chemotaxis, immune response modulation. The ARRB2 pathogenesis multiple myeloma (MM) has not been elucidated. This study addressed this question by evaluating expression bone marrow (BM) samples from newly diagnosed MM patients deriving correlations with key clinical outcomes. In light recent trends towards use checkpoint...
Accumulating evidence demonstrates the important roles of microRNAs (miRNAs) in tumor development and progression. miR-26a has been reported to be downregulated several types cancers including hepatocellular carcinoma, but underlying mechanism how is repressed remains largely unknown. In present study, we performed western blot analysis, qRT-PCR, luciferase reporter assay chromatin immunoprecipitation investigate relationship between enhancer zest homologue 2 (EZH2). CCK-8 colony formation...
Abstract We examined the association between breastfeeding practices and associated factors using cross‐sectional data from face‐to‐face interviews with 9,745 mother–child dyads in China. The study collected information on potential at individual, family, health facility environmental levels used survey commands Stata to consider sampling weight design effects. Although was norm (97.4% ever breastfed), prevalence of early initiation (EIBF) 0–11 months old 8.2%, exclusive (EBF) 0–5 27.8%...
(A) Outline of the synthesis CMCS-S-S-Py and (B) schematic depiction fabrication CMCS/BSA hydrogel its properties.
Production of L-sorbose from D-sorbitol by Gluconobacter oxydans is the first step to produce L-ascorbic acid on industrial scale. The sldhAB gene, which encodes sorbitol dehydrogenase (SLDH), was overexpressed in an strain G. WSH-003 with a strong promoter, P tufB . To enhance mRNA abundance, series artificial poly(A/T) tails were added 3'-terminal gene. Besides, their role overexpression and subsequent effects production investigated.The abundance gene could be enhanced suitable tails. By...