A5072589626- Plant Molecular Biology Research
- Light effects on plants
- Advanced Combustion Engine Technologies
- Photosynthetic Processes and Mechanisms
- Vehicle emissions and performance
- Engineering Applied Research
- Plant Stress Responses and Tolerance
- Catalytic Processes in Materials Science
- Analytical Methods in Pharmaceuticals
- Nanoparticle-Based Drug Delivery
- Hemoglobin structure and function
- Interconnection Networks and Systems
- Proteoglycans and glycosaminoglycans research
- Plant Parasitism and Resistance
- Drug Solubulity and Delivery Systems
- VLSI and Analog Circuit Testing
- VLSI and FPGA Design Techniques
- Combustion and flame dynamics
- Glycosylation and Glycoproteins Research
- NF-κB Signaling Pathways
- Advanced Drug Delivery Systems
- Plant tissue culture and regeneration
- Analytical Chemistry and Chromatography
- Plant Reproductive Biology
- Plant Gene Expression Analysis
Ajou University
2011-2025
Kyung Hee University
2019-2024
Seoul National University
2008-2023
Korea Disease Control and Prevention Agency
2022-2023
Yonsei University
2023
Pohang University of Science and Technology
2019
Hyundai Motors (South Korea)
2019
Pusan National University
2013
Instytut Farmaceutyczny
2013
Samil Pharm (South Korea)
2008-2013
Plants adjust their architecture to optimize growth and reproductive success under changing climates. Hypocotyl elongation is a pivotal morphogenic trait that profoundly influenced by light temperature conditions. While hypocotyl photomorphogenesis has been well characterized at the molecular level, mechanisms underlying thermomorphogenesis remains elusive. Here, we demonstrate E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) conveys warm signals thermomorphogenesis. To investigate...
In plants, necrotic lesions occur at the site of pathogen infection through hypersensitive response, which is followed by induction systemic acquired resistance (SAR) in distal tissues. Salicylic acid (SA) induces SAR activating NONEXPRESSER OF PATHOGENESIS-RELATED GENES1 (NPR1) an oligomer-to-monomer reaction. However, SA biosynthesis elevated only slightly tissues during SAR, implying that SA-mediated requires additional factors. Here, we demonstrated SA-independent signals induce a gene...
Plants exhibit diverse polar behaviors in response to directional and nondirectional environmental signals, termed tropic nastic movements, respectively. The ways which plants incorporate information into is well understood, but it less understood how stimuli, such as ambient temperatures, specify the polarity of behaviors. Here, we demonstrate that a developmentally programmed auxin flow underlies thermo-induced leaf hyponasty Arabidopsis (Arabidopsis thaliana). In warm environments,...
Summary The circadian clock control of CONSTANS ( CO ) transcription and the light‐mediated stabilization its encoded protein coordinately adjust photoperiodic flowering by triggering rhythmic expression floral integrator locus T FT ). Diurnal accumulation is modulated sequentially distinct E3 ubiquitin ligases, allowing peak to occur in late afternoon under long days. Here we show that abundance not simply targeted enzymes but also actively self‐adjusted through dynamic interactions between...
Paclitaxel-loaded hyaluronan solid nanoemulsions for enhanced treatment efficacy in ovarian cancer Joo-Eun Kim, Young-Joon Park College of Pharmacy, Ajou University, Suwon City, Republic Korea Abstract: (PTX-HSNs) were successfully fabricated the delivery PTX to improve via active tumor targeting. PTX-HSNs using high-pressure homogenization with a microfluidizer and lyophilized d-mannitol. Hyaluronan was coated on outside PTX-HSN sphere. The mean size maintained less than 100 nm, relatively...
Paclitaxel (PTX) is a effectively chemotherapeutic agent which extensively able to treat the non-small cell lung, pancreatic, breast and other cancers. But it practically insoluble drug with water solubility less than 1 µg/mL, restricts its therapeutic application. To overcome problem, hyaluronic acid-complexed paclitaxel nanoemulsions (HPNs) were prepared by ionic complexation of acid (HA) specifically target lung cancer. HPNs composed DL-α-tocopheryl acetate, soybean oil, polysorbate 80,...
Abstract In order to effectively remove alumina inclusions suspending in ultra‐low C steel during RH process, the dissolution kinetics of molten CaO–Al 2 O 3 –Fe t O–MgO–SiO oxide was investigated. A crucible technique used where allowed dissolve slag various conditions ((% CaO)/(% Al ), (% Fe O), temperature). The obtained data were interpreted using a kinetic mass transport equation obtain coefficient ( k m ) each condition. Increasing and temperature increased rate as well provided that...
Plant thermosensors help optimize plant development and architecture for ambient temperatures, morphogenic adaptation to warm temperatures has been extensively studied in recent years. Phytochrome B (phyB)-mediated thermosensing the gene regulatory networks governing thermomorphogenic responses are well understood at molecular level. However, it is unknown how plants manage their responsiveness fluctuating inducing behaviors. Here, we demonstrate that SUPPRESSOR OF MAX2 1 (SMAX1), known as a...
To better understand the epidemiology of SARS-CoV-2 reinfections, we analyzed national data from South Korean who were followed longitudinally January 2020 to April 2022. We conducted a nationwide retrospective cohort study estimate possible reinfection rates in all residents Korea, with at least two episodes laboratory-confirmed infection by reverse-transcriptase polymerase chain reaction or rapid antigen test (RAT) performed 45 more days between both episodes, and There 16 130 855 cases 55...
Surimi containing omega-3 fatty acids from algal oil was prepared by the addition of oil-in-water emulsions or bulk oil. Emulsion and were added separately to surimi provide approximately 500 mg per serving (85 g). Addition emulsion had no effect on gel strength, whereas decreased strength an average 31%. All treatments increased in Hunter b values due presence carotenoids Among cryoprotectants, sodium tripolyphosphate major additive responsible for retarding formation lipid hydroperoxides...
Increased interleukin (IL)-8 plays an important role not only in activation and recruitment of neutrophils but also inducing exaggerated angiogenesis at the inflamed site. In present study, we investigated fact that clotrimazole (CLT) inhibits intestinal inflammation, inhibitory action is mediated through suppression IL-8 expression. trinitrobenzene sulfonic acid (TNBS)-induced rat colitis model, CLT dose-dependently protected from TNBS-induced weight loss, colon ulceration, myeloperoxidase...
Abstract Background It is widely perceived that mechanical or thigmomorphogenic stimuli, such as rubbing and bending by passing animals, wind, raindrop, flooding, broadly influence plant growth developmental patterning. In particular, wind-driven stimulation known to induce the incidence of radial expansion shorter stockier statue. Wind also affects adaptive propagation root system in various species. However, it unknown how plants sense transmit wind-derived signals launch appropriate...
Reactive oxygen species (ROS) serve as critical signaling mediators in plant adaptation responses to environmental stimuli. ROS biosynthesis and metabolism should be tightly regulated, because they often impose oxidative damage on biological molecules, such DNA proteins, cellular structures. It is known that at high temperatures, rapidly accumulate tissues. Thus, a quick activation of ROS-scavenging systems necessary for thermal adaptation. However, it largely unknown how the thermo-induced...