A5100411869- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Renal and related cancers
- Allergic Rhinitis and Sensitization
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Peripheral Neuropathies and Disorders
- Adolescent and Pediatric Healthcare
- Global Healthcare and Medical Tourism
- Single-cell and spatial transcriptomics
- Sleep and Wakefulness Research
- Histone Deacetylase Inhibitors Research
- Nasal Surgery and Airway Studies
- Eosinophilic Esophagitis
- Pediatric Urology and Nephrology Studies
- IL-33, ST2, and ILC Pathways
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Diabetes Treatment and Management
- Dermatology and Skin Diseases
- Peptidase Inhibition and Analysis
- Systemic Lupus Erythematosus Research
- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Myopathies and Dermatomyositis
Sun Yat-sen University
2017-2025
Stomatology Hospital
2025
The First Affiliated Hospital, Sun Yat-sen University
2017-2023
Guangzhou Institute of Geochemistry
2023
Zero to Three
2022
National Health and Family Planning Commission
2020
Zhongshan Hospital
2017
Fudan University
2017
Background and aims Glycated hemoglobin A1c (HbA1c) ≥6.5% (or 48mmol/mol) has been recommended as a new diagnostic criterion for diabetes; however, limited literature is available regarding the effect of age on HbA1c diagnosing diabetes causes this remain unknown. In study, we investigated whether why affects efficiency in community-based Chinese population. Methods total, 4325 participants without previously known were enrolled study. Participants stratified by age. Receiver operating...
Abstract Background Renal fibrosis is the pathological foundation of various chronic kidney diseases progressing to end stage renal failure. However, there are currently no nephroprotective drugs targeted fibrotic process in clinical practice. Proteolytic targeting chimeras (PROTACs), which reversibly degrade target proteins through ubiquitin–proteasome pathway, a novel therapeutic modality. Smad3 key pathogenic factor fibrogenesis while HIF-2α exhibits prominent protective effects, natural...
Interleukin(IL)-25, IL-33, and thymic stromal lymphopoietin (TSLP) underlie the crosstalk between epithelial cells dendritic (DCs) during development of Th2 responses. This study aimed to measure expressions IL-17RB, ST2 TSLPR, receptor IL-25, TSLP respectively, on myeloid DCs in nasal polyps (NP) evaluate their association with local inflammation disease severity patients NP. Samples were collected from 30 NP 16 control subjects recruited prospectively. The mRNA expression cytokines,...
Dexmedetomidine (DEX) has been described as a safe sedative in clinical practice, but its effects on the pathophysiological traits of obstructive sleep apnea (OSA) are unclear. We estimated DEX sedation four key OSA (pharyngeal collapsibility, dilator muscle function, arousal threshold, and loop gain) adult patients with by conducting secondary analysis prospective diagnostic trial. Pathophysiological from polysomnography respiratory parameters under natural DEX-induced were compared....
Background: Glucocorticoids (GC) therapeutic response in patients with chronic rhinosinusitis nasal polyps (CRSwNP) varies markedly.Aims/Objectives: To compare the utility between subjective and objective assessment of GC sensitivity reflecting impact on systemic local eosinophilia CRSwNP patients.Material methods: Twenty-six were enrolled. All given 30 mg prednisone once daily for 7 days subsequently classified into subjectively GC-sensitive -insensitive subgroup or objectively subgroup....
Abstract Background Rehospitalization is a major problem for end stage renal disease (ESRD) populations. However, researches on 30-day unexpected rehospitalzation of incident peritoneal dialysis (PD) patients were limited. This study aimed to investigate the prevalence, risk factors and impact outcomes rehospitalization in PD patients. Methods was retrospective cohort study. Patients who accepted catheter implantation our centre from Jan 1, 2006 Dec 31, 2013 regular follow-up included. The...