Mingzhu Sun

ORCID: 0000-0003-0562-7665
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About
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Research Areas
  • Nerve injury and regeneration
  • Advanced Battery Materials and Technologies
  • Electrospun Nanofibers in Biomedical Applications
  • Advancements in Battery Materials
  • Neuroscience and Neural Engineering
  • Image Processing Techniques and Applications
  • Effects and risks of endocrine disrupting chemicals
  • Plant Reproductive Biology
  • Cell Image Analysis Techniques
  • Advanced Battery Technologies Research
  • Mesenchymal stem cell research
  • Theoretical and Computational Physics
  • Legume Nitrogen Fixing Symbiosis
  • Animal Virus Infections Studies
  • Plant Molecular Biology Research
  • Block Copolymer Self-Assembly
  • Zebrafish Biomedical Research Applications
  • Horticultural and Viticultural Research
  • Plant Gene Expression Analysis
  • Acupuncture Treatment Research Studies
  • Circadian rhythm and melatonin
  • Virus-based gene therapy research
  • Plant Stress Responses and Tolerance
  • Nerve Injury and Rehabilitation
  • Advanced battery technologies research

Xishuangbanna Tropical Botanical Garden
2025

Fudan University
1995-2024

Nankai University
2013-2024

Guangdong Medical College
2024

Zhejiang University
2021-2022

China Agricultural University
2010-2022

Nanjing Agricultural University
2022

Qingdao University of Science and Technology
2021

Jilin Normal University
2019-2020

Hebei University of Technology
2019

Summary Fleshy fruits are classically divided into climacteric and nonclimacteric types. It has long been thought that the ripening of is regulated by ethylene abscisic acid ( ABA ), respectively. Here, we report sucrose functions as a signal in strawberry F ragaria × ananassa fruit. Pharmacological experiments, well gain‐ loss‐of‐function studies, were performed to demonstrate critical role regulation fruit ripening. Fruit growth development closely correlated with change content. Exogenous...

10.1111/nph.12176 article EN New Phytologist 2013-02-21

Low temperature causes poor coloration of strawberry (Fragaria sp.) fruits, thus greatly reducing their commercial value. Strawberry fruits accumulate anthocyanins during ripening, but how low modulates anthocyanin accumulation in plants remains largely unknown. We identified MITOGEN-ACTIVATED PROTEIN KINASE3 (FvMAPK3) as an important negative regulator that mediates the response to temperature. FvMAPK3 activity was itself induced by temperature, leading repression via two mechanisms....

10.1093/plcell/koac006 article EN cc-by The Plant Cell 2022-01-07

The gold standard in surgical management of a peripheral nerve gap is currently autologous grafting. This confers patient morbidity and increases time therefore innovative experimental strategies towards engineering synthetic conduit are welcome. We have developed novel made poly ε-caprolactone (PCL) that has demonstrated promising regeneration short-term studies. material been engineered to permit translation into clinical practice here we demonstrate histological outcomes long-term vivo...

10.1016/j.neulet.2013.04.001 article EN cc-by Neuroscience Letters 2013-04-16

The S-passivated Mo<sub>2</sub>C behaves like a transition metal sulfide with strong binding to LiPSs, small LiPS conversion energy barrier, and low Li<sub>2</sub>S decomposition barrier.

10.1039/d0ta01217c article EN Journal of Materials Chemistry A 2020-01-01

Abstract Legume leaves exhibit diverse compound forms, with various regulatory mechanisms underlying the development. The transcription factor‐encoding KNOXI genes are required to promote leaflet initiation in most compound‐leafed angiosperms. In non‐IRLC (inverted repeat‐lacking clade) legumes, expressed leaf primordia but not others (IRLC). Recent studies have highlighted LFY genes' role regulating across legumes. functions development well understood IRLC legumes remain unclear Soybean, a...

10.1111/ppl.70092 article EN Physiologia Plantarum 2025-01-01

In an attempt to obviate the drawbacks of nerve autograft, ultrathin microporous biodegradable PCL and PCL/PLA films were tested for their compatibility with motor neuron-like NG108-15 cells primary Schwann cells. Data obtained from MTS colorimetric DNA fluorimetric assays showed that both cell lines readily attached proliferated on these materials. Images taken using scanning electron microscope fluorescence confirmed observations. Enhanced cell-surface interaction was achieved by...

10.1002/jbm.a.32681 article EN Journal of Biomedical Materials Research Part A 2009-12-04

10.1007/s10856-008-3671-3 article EN Journal of Materials Science Materials in Medicine 2009-01-09

The intensity of the root-sourced abscisic acid (ABA) signal has long been thought to decrease along its long-distance transport pathway, and hence shoot responses ABA would be expected become less sensitive with increase in plant height. It is reported here that there a significant modification pathway leaves grapevine (Vitis riparia×Vitis labrusca), but contrast expectation may it was found gradually intensified vine for as 3 m under both water-stressed non-stressed conditions. Consistent...

10.1093/jxb/erq390 article EN Journal of Experimental Botany 2010-12-03

A parallel algorithm designed for widely used distributed computer clusters is developed the real-space self-consistent-field theory polymers. We adopt an efficient data partition method to ensure high performance of this on clusters, which enables us explore unknown phase structures complex block polymers with accuracy and efficiency. As a benchmark test, applied ABC linear triblock copolymer, in volume fractions two end blocks polymer chain are equal (f_(A)=f_(C)) , simplify discussion....

10.1103/physreve.77.016701 article EN Physical Review E 2008-01-03

Abstract To overcome the disadvantages of autografts for peripheral nerve repair, different methods such as artificial conduits have been investigated an alternative approach. This study demonstrated that solvent casting is a simple but efficient method to create thin polyester‐based scaffolds stem cell delivery. Using poly (ε‐caprolactone) and ( D , L ‐lactic acid), we produced scaffold films containing heterogenous depressions (pits) on air surface with size ranging from 0.5 30 μm 2 ....

10.1002/jbm.a.32889 article EN Journal of Biomedical Materials Research Part A 2010-08-19

Sodium propionate is widely used as a preservative in food. The widespread use of preservatives known to cause both environmental and public health problems. This study aimed investigate the effects sodium on developmental behavior glucose metabolism zebrafish. Our results showed that had no significant effect embryonic morphological development zebrafish embryos but changed head eye area. Then we found disturbed thigmotaxis behavior, impaired neural development. Moreover, changes clock gene...

10.1016/j.ecoenv.2022.113791 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2022-06-23

Decabromodiphenyl ethane (DBDPE) is a novel retardant. DBDPE used in various flammable consumer products such as electronics, building materials, textiles, and children's toys. The presence of humans makes it extremely urgent to assess the health effects exposure. Here, we female mice an animal model investigate on embryonic development offspring health. results showed that 50 μg/kg bw/day exposure did not affect spindle rotation oocytes after fertilization, but led decrease pronuclei (PN)...

10.1096/fj.202200586r article EN The FASEB Journal 2022-07-11

The microphase ordering processes for ABC linear triblock copolymers are investigated using dynamic density functional theory (DDFT). implementation of the DDFT is verified by comparing 2D equilibrium morphologies it predicted with previous and experiments. Quenched from a disordered state, separation may proceed through either one-step or two-step mechanism, depending on composition interaction energies three components. When volume fraction one species dominates other two, always proceeds...

10.1021/ma051355b article EN Macromolecules 2005-10-01

Ocean acidification (OA) has posed formidable threats to marine calcifiers. In response elevated CO2 levels, calcifiers have developed multiple strategies survive, such as taking advantage of apoptosis, but its regulation mechanism remains largely unknown. Here, we used the Pacific oyster Crassostrea gigas model understand apoptotic responses and at short- (7 d) long-term (56 exposure (pH = 7.50). The apoptosis hemocytes was significantly induced after short-term treatment (7–21 suppressed...

10.1016/j.ecoenv.2021.112235 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-04-16

Abstract Purinergic receptor P2Y11, a G protein-coupled that is stimulated by extracellular ATP, has been demonstrated to be related the chemotaxis of granulocytes, apoptosis neutrophils, and secretion cytokines in vitro. P2Y11 mutations were associated with narcolepsy. However, little known about roles P2RY11 occurrence narcolepsy inflammatory response vivo. In this study, we generated zebrafish mutant using CRISPR/Cas9 genome editing replicated narcolepsy-like features including reduced...

10.1007/s10565-024-09882-5 article EN cc-by Cell Biology and Toxicology 2024-05-21

Hydroquinone(HQ) is a widely used industrial raw material and topical lightening product found in over-the-counter products. However, inappropriate exposure to HQ can pose certain health hazards. This study aims explore the mechanisms of DNA damage cell apoptosis caused by HQ, with focus on whether activates nuclear factor-κB (NF-κB) pathway participate this process investigate correlation between NF-κB activation poly(ADP-ribose) polymerase 1(PARP1). Through various experimental techniques,...

10.1021/acs.chemrestox.4c00135 article EN Chemical Research in Toxicology 2024-06-05

Abstract Protein tyrosine phosphatases (PTPases) have long been thought to be activated by reductants and deactivated oxidants, owing the presence of a crucial sulfhydryl group in their catalytic centers. In this article, we report purification characterization Reductant-Inhibited PTPase1 (ZmRIP1) from maize (Zea mays) coleoptiles, show that PTPase has unique mode redox regulation signaling. Surprisingly, ZmRIP1 was found reductant. A cysteine (Cys) residue (Cys-181) near active center...

10.1104/pp.111.191510 article EN PLANT PHYSIOLOGY 2012-04-23
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