- Substance Abuse Treatment and Outcomes
- Mental Health Treatment and Access
- Opioid Use Disorder Treatment
- Attention Deficit Hyperactivity Disorder
- Alcoholism and Thiamine Deficiency
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Homelessness and Social Issues
- Alcohol Consumption and Health Effects
- Neurological and metabolic disorders
- Cannabis and Cannabinoid Research
- Functional Brain Connectivity Studies
- Digital Mental Health Interventions
- HIV, Drug Use, Sexual Risk
- Religion, Spirituality, and Psychology
- Intimate Partner and Family Violence
- Infectious Encephalopathies and Encephalitis
- Obesity, Physical Activity, Diet
- Genetic Associations and Epidemiology
- COVID-19 and Mental Health
- Prenatal Substance Exposure Effects
- Forensic Toxicology and Drug Analysis
- School Health and Nursing Education
- Personality Disorders and Psychopathology
National Institute of Mental Health and Neurosciences
2016-2025
Queen Mary University of London
2024
Institute of Mental Health
2022-2024
Creative Commons
2023
Yale University
2018
Jawaharlal Institute of Post Graduate Medical Education and Research
2016
Marymount University
2015
TIFR Centre for Applicable Mathematics
2015
SRM Institute of Science and Technology
2012
Objective: To study the influence of spiritual well being (Sp WB) on symptoms distress, depression, and other dimensions quality life in advanced cancer patients receiving palliative care. Materials Methods: The was cross-sectional nature. Fifty with from a hospice were assessed following instruments: visual analog scale for pain (VAP), M.D. Anderson symptom inventory (MDASI), Hospital Anxiety Depression Scale (HADS), Functional assessment therapy - Palliative Care (FACT-pal), chronic...
To assess the impact of COVID-19-related lockdown in India on alcohol-dependent persons.We examined change incidence severe alcohol withdrawal syndrome presenting to hospitals city Bangalore.A changepoint analysis time series data (between 01.01.20 11.04.20) showed an increase average number cases from 4 8 per day (likelihood ratio test: χ2 = 72, df 2, P < 0.001).An unintended consequence was serious illness some patients with use disorders.
This study aims to find if the incidence and pattern of traumatic brain injury (TBI) changed during COVID-19pandemic. We also aim build an explanatory model for change in TBI using Google community mobility alcohol sales data.
There is emerging evidence that there are shared genetic, environmental and developmental risk factors in psychiatry, cut across traditional diagnostic boundaries. With this background, the Discovery biology of neuropsychiatric syndromes (DBNS) proposes to recruit patients from five different (schizophrenia, bipolar disorder, obsessive compulsive Alzheimer's dementia substance use disorders), identify those with multiple affected relatives, invite these families participate study. The will...
Abstract Lithium is an effective, well-established treatment for bipolar disorder (BD). However, the mechanisms of its action, and reasons variations in clinical response, are unclear. We used neural precursor cells (NPCs) lymphoblastoid cell lines (LCLs), from BD patients characterized response to lithium (using “Alda scale” “NIMH Retrospective Life chart method”), interrogate cellular phenotypes related both disease response. NPCs two biologically who differed their were compared with...
Background: Tapentadol is a dual action opioid analgesic with emerging data on abuse and diversion. Aim: This study describes tapentadol abuse, clinical presentation, treatment patterns. Methods: We reviewed patients seeking help for use (2017–2023) at South Indian tertiary hospital. collected sociodemographics, profiles, treatment, including buprenorphine dose limiting side effects. Results: Of 933 disorder cases, 228 involved tapentadol. Most (89%) initiated tapentadol, 93% injected...
Background: Group intervention is highly effective for survivors of IPV. There are fewer interventions available intimate partner violence in addiction treatment settings India. Aim: To develop and validate the group module women Materials Methods: The manual was developed by assessing psychosocial needs (n = 20) subject experts’ opinions 7). validated using content validation index kappa value. Results: components were IPV who seeking their spouse’s alcohol dependence. include sharing...
Fluoroquinolones can cause adverse neuropsychiatric side effects, which are more common in older age. We present three cases of levofloxacin-induced acute anxiety and insomnia young adults. In all the cases, discontinuation levofloxacin immediately lead to remission.
Tamoxifen has both antagonistic and agonistic tissue-specific actions. It can have a paradoxical estrogenic effect on lipid metabolism resulting in elevated triglyceride chylomicron levels. This cause life-threatening complications like acute pancreatitis. To our knowledge, very few cases of tamoxifen-induced pancreatitis been reported the literature. We report case severe hypertriglyceridemia following tamoxifen use. A 50-year-old diabetic lady was (20mg/day) hormonal therapy for breast...
Adult ADHD is a prevalent yet underdiagnosed and undertreated condition. Assessment of critical to understanding managing comprehensively. Method: Scholarly articles on adult between 1996 2022 were reviewed using the PRISMA guidelines. rating scales with multiple citations selected their psychometric properties symptom coverage analyzed. Results: Ten scales, sound properties, identified. Out those two (BADDS BAARS-IV) load inattentive domain ADHD, while rest focus comprehensive assessment...
Background: To examine the perspectives of mental health professionals on providing group intervention for female spouses men with alcohol dependence who experienced intimate partner violence (IPV). Methods: A qualitative research design was used, and a purposive sample technique used to select participants. Nine experts more than five years experience in handling cases provided insights through in-depth interviews. The transcripts were carefully examined several times, coded re-coded. codes...
Background: People with alcohol use disorders (AUDs) have varied needs while they seek treatment. Understanding and focusing on the will improve treatment outcomes. The objective of study is to qualitatively assess treatment-related patients AUDs admitted a tertiary care center. Methods: A semi-structured questionnaire anchor questions was developed based literature review key informant interviews. All interviews were audio recorded, transcribed, color-coded manually. Two reviewers reviewed...
Addiction or Substance Use Disorders (SUD) is a growing public health problem in India. There are very few trained professionals to provide evidence based care for these conditions. We initiated weekly tele-ECHO clinic train the recognition and management of Alcohol tobacco use disorders. The preliminary results points towards feasibility as well acceptability ECHO model training addiction mental health. need more involvement providers future NIMHANS Programs.
Article AbstractObjective: To examine the clinical characteristics and course of benzodiazepine "Z-drug" dependence in patients presenting to a tertiary deaddiction center southern India. Methods: Case files 950 inpatients admitted between January 2007 2014 who reported or Z-drug use were reviewed. Patients (n = 170) with an ICD-10 diagnosis mental behavioral disorders due sedatives hypnotics-dependence syndrome currently using substance (F13.24) included this study.Results: Alprazolam 86,...
To define the prevalence and clinical presentation of pellagra, a multi-systemic disease caused by deficiency niacin, in patients admitted to tertiary addiction treatment centre southern India, with alcohol dependence syndrome (ADS)-(ICD10).Review health records 2947 who received inpatient care for ADS between 2015 2017.Out 2947, 31 (1%) were diagnosed pellagra. Nearly two-thirds (64.5%) those pellagra from low-income group. Of clinical-triad all had dermatitis, more than half (58%)...
Zolpidem, an imidazoline nonbenzodiazepine sedative drug, is used widely. Initial reports showed minimal abuse potential. However, multiple have appeared of dose escalation and abuse. Subjective effects high-dose zolpidem are not known. In light accumulating evidence potential, we hereby report a case dependence review relevant literature. A 33-year-old male presented with 5 years daily use 600–1700 mg tartrate. He reported subjective euphoria, intense craving, inability to stop use. Loss...
Alcohol dependence is a global concern. Baclofen has shown promise as an anti-craving agent but its efficiency remains to be settled. We reviewed 549 male cases diagnosed with alcohol who received Acamprosate (201) or (348). 'Time first drink' was compared between two groups and multiple regression analysis done in baclofen group identify correlates of effectiveness. There significant difference outcome measure (M = 4.44, SD 3.75) 3.73, 2.19); t (547) 2.45, P 0.01. Initial six predictor...
Adverse childhood experiences are linked to the development of a number psychiatric illnesses in adulthood. Our study examined pattern adverse and their relation age onset major conditions individuals from families that had ⩾2 first-degree relatives with (multiplex families), identified as part an ongoing longitudinal study.Our sample consisted 509 215 families. Of these, 268 were affected, i.e., diagnosed bipolar disorder (n = 61), obsessive-compulsive 58), schizophrenia 52), substance...
Despite the notion of stigma as a socio-cultural process with concept rooted in social space rather than individual space, global studies examining impact cultural differences on toward substance use disorders are lacking.In this study, we aim to study influence national culture alcohol and disorders.We analyzed individual-level data from 68,041 respondents 49 countries disorders. We examined effect dimensions consumption rates using hierarchical linear modeling.Our modeling results indicate...
Externalizing disorders of childhood characterized by attention deficit hyperactivity disorder (ADHD), conduct and oppositional defiant are well known to predispose an individual experiment with substances at early age the later lead development substance use (SUD). ADHD, a developmental disorder, persists into adulthood in about two-thirds cases.In present study, we aimed explore prevalence ADHD its subtypes treatment-seeking patients SUD outpatient setting. Secondarily, also compare scores...