A5043812236- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Mosquito-borne diseases and control
- Malaria Research and Control
- Viral Infections and Vectors
- RNA Interference and Gene Delivery
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Infection Control and Ventilation
- Clay minerals and soil interactions
- Vibrio bacteria research studies
- Calcium Carbonate Crystallization and Inhibition
- Vaccine Coverage and Hesitancy
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Vector-borne infectious diseases
- Soil and Unsaturated Flow
- Virus-based gene therapy research
Johannes Gutenberg University Mainz
2021-2024
University Medical Center of the Johannes Gutenberg University Mainz
2021-2024
Zentrum für Kinderheilkunde
2021-2024
University of Copenhagen
2014-2023
Centre of Excellence for Health, Immunity and Infections
2023
Rigshospitalet
2023
Older age and chronic disease are important risk factors for developing severe COVID-19. At population level, vaccine-induced immunity substantially reduces the of COVID-19 hospitalization. However, relative impact humoral cellular on protection from breakthrough infection is not fully understood.In a study cohort 655 primarily older participants (median 63 years (IQR: 51-72)), we determined serum levels Spike IgG antibodies using Multiantigen Serological Assay quantified frequency...
We investigated the adhesion of two functional groups to α-alumina as a model for adsorption organic molecules on clay minerals. Interactions between compounds and minerals play an important role in processes such drinking water treatment, remediation contaminated soil, oil recovery, fabricating complicated nanomaterials, there have been claims that compound-clay mineral interaction created ordering is necessary genesis life. In many organisms, biominerals makes it possible control growth...
We assessed the seroepidemiology of SARS-CoV-2 infection and incidence coronavirus disease 2019 (COVID-19) before during rollout COVID-19 vaccines, in a prospective observational cohort study on healthcare workers (HCWs) large tertiary hospital Mainz, Germany. Antibody status was six visits between September 2020 February 2022. Self-reported symptoms were collected using smartphone application; symptomatic HCWs tested real-time polymerase chain reaction (RT-PCR) assays for SARS-CoV-2. Rates...
Acute febrile diseases transmitted by mosquitos are a diagnostic challenge for pediatricians working in sub-Saharan Africa. Misclassification due to the lack of rapid, reliable tests leads overuse antibiotics and antimalarials. Children presenting with acute fever suspected having malaria were examined at health care facilities Mwanza Region Tanzania. The sensitivity specificity blood smear microscopy rapid that targeted histidine-rich protein 2 Plasmodium lactate dehydrogenase compared...
CV-NCOV-005 was conducted to generate additional safety and immunogenicity data for the former CVnCoV SARS-CoV-2 mRNA vaccine candidate in healthcare workers (HCW). Randomised, observer blinded, placebo-controlled, phase 3 trial performed at University Medical Center Mainz, Germany. HCWs aged ≥ 18 years with no history of infection/positive serology were randomly assigned receive two doses CVnCoV, or placebo (0.9 % NaCl). The primary objectives expand database assess antibody responses...
Abstract Background Acute febrile diseases transmitted by mosquitos are a diagnostic challenge for pediatricians working Sub-Sahara-Africa. Misclassification due to the lack of rapid, reliable tests leads overuse antibiotics and antimalarials. Methods Between April 2016 March 2018, 751 children presenting with acute fever suspected having malaria were examined at healthcare facilities located in Mwanza Region, Tanzania. Sociodemographic data medical histories obtained. The sensitivity...
Abstract Background Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. We assessed incidence infection and COVID-19 before the roll out vaccines in a cohort HCWs Mainz, Germany. Methods Using prospective observational design, antibody status was baseline every 6 weeks (±2 weeks). Daily self-reported symptoms were collected using smartphone application. Symptomatic tested RT-PCR. estimated symptomatic asymptomatic rates based on two case definitions varying sensitivity...
Background: Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. We followed a large cohort HCWs in Germany to assess the incidence infection and COVID-19 disease before introduction vaccines.Methods: present interim data, collected from August 2020 January 2021 ′CPMprevac′ study, an ongoing prospective observational study including University Medical Centre Mainz Germany. Antibody status was assessed baseline every 6 weeks (±2 weeks). Daily self-reported symptoms were...