A5082507465- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Genetic and rare skin diseases.
- Autoimmune and Inflammatory Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Retinoids in leukemia and cellular processes
- Spondyloarthritis Studies and Treatments
- Systemic Sclerosis and Related Diseases
- Hair Growth and Disorders
- Skin Protection and Aging
- Skin Diseases and Diabetes
- Allergic Rhinitis and Sensitization
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders Research
- T-cell and B-cell Immunology
- Cancer and Skin Lesions
- Mast cells and histamine
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dermatological and Skeletal Disorders
University of Milan
2010-2019
Istituto Ortopedico Galeazzi
2010-2019
Istituti di Ricovero e Cura a Carattere Scientifico
2006-2016
Institute of Dermatology
2010
Ospedale Maggiore
1997-2003
New York University
1990
Columbia University Irving Medical Center
1990
Mario Negri Institute for Pharmacological Research
1989
Istituto di Sessuologia Clinica
1987
Sensitization to orthopaedic implant materials is an unpredictable event that might affect performance.In candidates for hip or knee joint prosthesis implantation, evaluate preoperative assessments identifying patients with metal sensitivity, determine the percentage of who developed sensitivity at 1 year after and examine clinical relevance patch tests lymphocyte transformation (LTT-MELISA®) evaluation sensitization.A total 100 referred arthroplasty were assessed preoperatively then...
An observational study was conducted to estimate the incidence of psoriasis in Italy, as well utilization healthcare resources and association with selected comorbidities patients. The data source Health Search/Thales Database, containing computer-based patient records from over 900 primary care physicians (PCPs) throughout Italy. cohort comprised all adults receiving a first-ever diagnosis during years 2001-2005. From total sample 511,532 individuals, 2.30-3.21 cases per 1,000 person-years....
Psoriasis and atopic dermatitis (AD) are chronic inflammatory skin diseases, which negatively influence the quality of life. In last years, several evidences highlighted pivotal role bacteria in worsening symptomatology AD psoriasis. present study we evaluated microbiota composition accurately selected subjects affected by psoriasis.Three first cousins were chosen for according to strict selection criteria. One subject was moderate AD, one had psoriasis included as healthy control. Two...
Abstract In this paper we report 19 patients (14 males, 5 females; mean age 28.16 years ± 7.68 SD) out of a series 23 (17 females) who developed mood disturbance (moderate to severe depression) during treatment with finasteride, 1 mg/day orally, for androgenetic alopecia (Hamilton subtypes III–V; Ludwig I–II). Depression, which significatively impaired sociofamilial relations, sleep and eating behaviour, was associated marked anxiety in some cases, after 9–19 weeks promptly resolved...
Psoriasis is a chronic inflammatory, immune-mediated skin disorder that affects 1.5-1.8 million people in Italy. The most common form of the disease plaque psoriasis, affecting about 90% psoriasis patients, with 20%-30% them suffering from moderate or severe condition. Little information available economic impact European countries. primary objective this study was to perform cost-of-illness analysis patients and Therefore, direct, indirect costs, intangible costs (quality life - QoL) were...
BackgroundAntibodies against tumor necrosis factor represent an effective therapy for patients with inflammatory bowel disease. Despite their successful results, the exact mechanism by which infliximab suppresses intestinal inflammation is still a matter of debate. In this study, we used translational approach to identify key mechanisms associated resolution mucosal induced infliximab.
Abstract The aim of this study is to identify subsets T cells differentially represented in the circulation patients with psoriatic arthritis and evaluate possibility that they can recirculate between peripheral blood inflamed joints. We analyzed phenotype cytokine expression circulating CD8 + CD4 69 subjects: 28 cutaneous psoriasis, 15 arthritis, 26 healthy subjects. In circulation, percentage each subset was compared among groups correlation calculated serum concentration C-reactive...
Actinic keratosis (AK) is a common keratinocyte intra-epidermal neoplasia. To assess AK prevalence and potential risk factors in patients attending Italian general dermatology clinics. This retrospective study was conducted on clinical data from consecutive white outpatients aged ≥30 years, 24 clinics between December 2014 February 2015. (entire population) multivariate factor analysis (patients with current/previous complete data) are presented. 7,284 27.4% (95% CI: 26.4-28.4%); 34.3% men...
Serum levels of retinol-binding protein (the specific carrier vitamin A) were measured in eleven patients with pityriasis rubra pilaris and some their close relatives. The level was markedly reduced every patient, the It is postulated that defective synthesis a biochemical marker for pilaris, probably transmitted as Mendelian dominant.
We evaluated risk factors such as socio-demographic characteristics, smoking habits and alcohol consumption, associated with hypertension, diabetes obesity in psoriasis patients, order to plan health education programs that could prevent the onset or progression of co-morbidities. The study population consisted 1376 patients who were consecutively recruited at 21 Italian Departments Dermatology. Information concerning variables, presence chronic disorders type 2 was collected. co-morbidities...
Journal Article One‐year safety and efficacy of ustekinumab results dose adjustment after switching from inadequate methotrexate treatment: the TRANSIT randomized trial in moderate‐to‐severe plaque psoriasis Get access K. Reich, Reich Dermatologikum Hamburg Stephansplatz 5 20354 GermanyGeorg‐August‐University Göttingen Germany Correspondence Kristian Reich. E‐mail: kreich@dermatologikum.de Search for other works by this author on: Oxford Academic Google Scholar L. Puig, Puig Department...
The aim of this study was to assess quality life in patients with scalp dermatitis using the Italian version Scalpdex, and validate instrument Italian. survey conducted outpatients psoriasis, seborrhoeic dermatitis, alopecia, or follicular lichen. Data were completed on 194 patients, 78% whom had psoriasis. Scalpdex scores always higher women than men, younger people compared elderly people. most frequent items were: being ashamed, embarrassed, bleeding scalp, feeling self-conscious,...
To evaluate the efficacy of a highly concentrated Lactobacillus salivarius preparation containing gelling complex formed by Streptococcus thermophilus ST10 and tara gum in treatment atopic dermatitis (AD).Previous studies have demonstrated an improvement AD symptoms after administration probiotic strain L. LS01. S. create that adheres to intestinal mucus improves barrier function.A prospective, controlled pilot trial was carried out how association could improve activity LS01 administered at...
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Cyclosporine A (CsA) effectively controls psoriasis, however, its long-term continuous use is not recommended. This study aims to evaluate the efficacy and tolerability of week-end CsA microemulsion for reduction relapse rate in patients with chronic plaque psoriasis who had achieved clinical remission following therapy. The PREWENT (Psoriasis Relapse Evaluation Week-End Neoral Treatment) was a 24 week, randomized, double-blind, multicenter study, carried out 22 Italian hospital or...