A5101165285- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Cardiovascular Health and Disease Prevention
- Colorectal Cancer Screening and Detection
- Gastrointestinal disorders and treatments
- Dysphagia Assessment and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Gut microbiota and health
- Gastrointestinal motility and disorders
- Probiotics and Fermented Foods
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Inflammatory Bowel Disease
- Metastasis and carcinoma case studies
- Neurological Disease Mechanisms and Treatments
- Genetic factors in colorectal cancer
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Catalytic C–H Functionalization Methods
- Cerebrovascular and genetic disorders
Material (Belgium)
2025
Guangdong Academy of Medical Sciences
2023-2025
Southern Medical University
2023-2025
Guangdong Provincial People's Hospital
2023-2025
Chenzhou First People's Hospital
2019-2025
Division of Chemistry
2025
Xi'an Jiaotong University
2023-2025
Zhengzhou People's Hospital
2024
Shaanxi Provincial People's Hospital
2024
University of North Carolina at Chapel Hill
2024
Abstract Background The hypocholesterolemic effects of lactic acid bacteria (LAB) have now become an area great interest and controversy for many scientists. In this study, we evaluated the Lactobacillus plantarum 9-41-A fermentum M1-16 on body weight, lipid metabolism intestinal microflora rats fed a high-cholesterol diet. Methods Forty were assigned to four groups either normal or LAB-treated received diet supplemented with M1-16. sacrificed after 6-week feeding period. Body weights,...
The objective of the present study was to evaluate predictive values percent body fat (PBF) and mass index (BMI) for cardiovascular risk factors, especially when PBF BMI are conflicting. calculated by standard formula determined bioelectrical impedance analysis. A total 3859 ambulatory adult Han Chinese subjects (2173 males 1686 females, age range: 18-85 years) without a history diseases were recruited from February September 2009. Based on PBF, they classified into group 1 (normal N =...
The IL23/Th17 pathway is essential for the onset of inflammatory bowel disease (IBD), yet specific mechanism by which this initiates remains unknown. In study, we identify mechanisms that mediate cross-talk between IL23 and intestinal barrier in IBD. downstream targets were identified RNA array profiling confirmed immunohistochemical staining. role miRNAs interact with was explored mice TNBS-induced colitis. Claudin-8 (CLDN8), a multigene family protein constitutes backbone tight junctions,...
Abstract MicroRNAs are critical post-transcriptional regulators of gene expression and key mediators pathophysiology inflammatory bowel disease (IBD). This study is aimed to the role miR-665 in progression IBD. Real-time PCR analysis was used determine 89 freshly isolated IBD samples dextran sulfate sodium (DSS)-induced colonic mucosal tissues. The inducing apoptosis colitis were examined by Annexin V, TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling) staining, colony...
Peroral endoscopic myotomy (POEM) has been developed as a minimally invasive treatment for achalasia years. However, the optimal length of submucosal tunnel and muscle bundles during procedure POEM not yet determined, so we aim to assess safety efficacy modified with shorter in patients. Consecutive patients had performed myotomy, assessed by symptoms, high-resolution manometry, barium swallow examinations before 3 months after evaluation. Modified (mean 6.8 cm) (total mean 5.4 were...
Abstract Background and study aims For bowel preparation, using a reduced volume of polyethylene glycol (PEG) solution without influencing its effectiveness would be preferable. While simethicone shows great potential as an adjunctive agent, data on use are limited. We aimed to clarify whether added low-volume PEG improved cleansing. Patients methods Consecutive adult patients registered for colonoscopy were recruited from seven medical centers in South China between 15 April July 2015...
Background Nasal septum perforation represents a significant clinical concern, with limited investigations into the role of medications in its etiology. This study utilizes FDA Adverse Event Reporting System (FAERS) database to identify drugs associated nasal and assess their risk.
A class of prearomatic carboxylic acid p-quinol ester radical precursors has been developed successfully, which could undergo homolytic cleavage the para C-O bond esters via pyridine-boryl radical-induced aromatization in presence pyridines and diboron reagents, affording corresponding alkyl decarboxylation from carboxyl situ. In addition, were further applied substitution with phenylsulfonyl compounds self-coulpings. This method not only provides a new approach to generation intermediate...
Statins have been recommended by several guidelines as the primary prevention medication for cardiovascular diseases. However, benefits of statin therapy cerebral small vessel disease (CSVD), particularly in adults ≥75 years age, not fully evaluated.
AIM:To investigate the therapeutic effects of four strains probiotics (E.feacalis , L. acidophilus C. butyricum and B. adolescentis ) on dextran sulphate sodium (DSS)-induced experimental colitis in Balb/c mice. METHODS:Eighty mice were randomly divided into 8 groups.Weight-loss, fecal character, occult blood hematochezia recorded daily.Disease activity index (DAI) scores also evaluated everyday.Length colon was measured histological 13th day.Myeloperoxidase (MPO) detected.Interleukin-1...
Long-term Helicobacter pylori infection leads to chronic gastritis, peptic ulcer, and gastric malignancies. Indigenous microflora in alimentary tract maintains a colonization barrier against pathogenic microorganisms. This study is aimed observe the duodenum alteration after H. Mongolian Gerbils model.A total of 18 gerbils were randomly divided into two groups: control group that given NCTC J99 strain intragastrically. After 12 weeks, was identified by rapid urease tests bacterial culture....
Ingestion of foreign bodies (FBs) in the upper esophagus is common South China. It difficult to manage because limited working space and inadequate visual field this area. This randomized, controlled study aimed evaluate usefulness a transparent cap endoscopic management FBs esophagus.Adult patients suspected based on history ingestion, symptoms, barium contrast examination were screened for between March 1, 2009 December 31, 2010. Seventy with endoscopic-confirmed recruited randomly...
Anti-reflux barrier dysfunction is one of the primary mechanisms in gastroesophageal reflux disease (GERD) pathogenesis. The esophagogastric junction contractile integral (EGJ-CI) a new metric adopted to evaluate EGJ contractility, which implies antireflux function. aim current study was validate this patients with GERD and its correlation esophageal acid exposure, as well efficacy proton pump inhibitor treatment.Ninety-eight 21 healthy controls were included study. Upper endoscopy,...
Abstract Background Although it is accepted that the etiology of cerebral small vessel disease (CSVD) associated with cardiovascular risk factors, association between CSVD and circadian rhythm blood pressure (BP) unclear. We aimed to determine if such an existed in elderly population. Method White matter hyperintensities (WMHs), lacunes, microbleeds, nocturnal dipping pattern (NDP), morning surge systolic (SBP) were assessed 2,091 participants ≥60 years age. Results During average 63 months...