- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Bone Tumor Diagnosis and Treatments
- Vascular Tumors and Angiosarcomas
- Radiomics and Machine Learning in Medical Imaging
- Musculoskeletal synovial abnormalities and treatments
- Colorectal and Anal Carcinomas
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumors and treatment
- Lanthanide and Transition Metal Complexes
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Atomic and Subatomic Physics Research
- Surgical site infection prevention
Centre Léon Bérard
2019-2023
Institut d’Hématologie et d’Oncologie Pédiatrique
2023
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
2022
Inserm
2022
Université Claude Bernard Lyon 1
2022
Centre National de la Recherche Scientifique
2022
Centre de Recherche en Cancérologie de Lyon
2020
Appropriate imaging is essential in the treatment of children and adolescents with rhabdomyosarcoma. For adequate stratification optimal individualised local utilising surgery radiotherapy, high-quality crucial. The paediatric radiologist, therefore, an member multi-disciplinary team providing clinical care research. This manuscript presents European rhabdomyosarcoma guideline, based on recently developed guideline Paediatric Soft Tissue Sarcoma Study Group (EpSSG) Imaging Committee. was...
Histologic response to chemotherapy for osteosarcoma is one of the most important prognostic factors survival, but assessment occurs after surgery. Although tumor imaging used surgical planning and follow-up, it lacks predictive value. Therefore, a radiomics model was developed predict neoadjuvant based on pretreatment T1-weighted contrast-enhanced MRI. A total 176 patients (median age, 20 years [range, 5–71 years]; 107 male patients) with treated surgery between January 2007 December 2018...
The objective of this study was to evaluate the efficacy and safety adjuvant radiotherapy (aRT) in patients with soft-tissue sarcoma (STS) re-excised after unplanned tumor resection (UPR).From 2000 2015, we retrospectively evaluated STS limb or trunk who underwent post-UPR re-excision our expert center received not aRT.Median follow-up 121 months (IQR 94-165). Among 145 patients, 37 were treated aRT (no-RT) 108 a median radiation dose 50 Gy 50-60). At 10 years, no-RT groups showed cumulative...
Rationale CSF1R tyrosine kinase inhibitors (TKI) and antibodies yield response rates tumor control in patients with diffuse type tenosynovial giant cell tumors (dTGCT). The long term management of dTGCT treated TKI is however not known. Patients methods We conducted a retrospective single center study on the 39 advanced and/or inoperable referred to Centre Leon Berard for medical treatment. clinical characteristics treatments who had received at least one line or Ab was collected from...
Abstract Background The aim of this study was to assess the clinical impact indeterminate pulmonary nodules (no more than four less 5 mm or one nodule measuring between and 10 by computed tomography [CT]) in children adolescents with adult‐type non‐rhabdomyosarcoma soft tissue sarcoma (NRSTS) at diagnosis. Methods Patients NRSTS treated 11 centers as part European paediatric Soft Tissue Sarcoma Study Group (EpSSG) were retrospectively assessed. Local radiologists, blinded information except...
To investigate the feasibility of diffusion-weighted magnetic resonance imaging (DW-MRI) as a predictive marker after neoadjuvant chemotherapy in patients with rhabdomyosarcoma.We performed multicenter retrospective study including pediatric, adolescent and young adult rhabdomyosarcoma, Intergroup Rhabdomyosarcoma Study group III/IV, treated according to European paediatric Soft tissue sarcoma Group (EpSSG) RMS2005 or MTS2008 studies. DW-MRI was institutional protocols. We two-dimensional...
Introduction: Gadolinium deposition in the human brain, especially Globus Pallidus (GP) and Dentate Nucleus (DN) has been reported after administration of linear Gadolinium-Based Contrast Agents (GBCAs). This study aims to determine whether repeated injections macrocyclic GBCA are associated with an increased Signal Intensity (SI) on T1-weighted sequences oncologic pediatric patients. Materials methods: retrospective monocentric cohort included consecutive children at least two MRIs...