A5030658246- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease and Transplantation
- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Liver Disease Diagnosis and Treatment
- Radiation Dose and Imaging
- Orthopaedic implants and arthroplasty
- Lysosomal Storage Disorders Research
- Cystic Fibrosis Research Advances
- Adrenal and Paraganglionic Tumors
- Advanced MRI Techniques and Applications
- Congenital Diaphragmatic Hernia Studies
- Pediatric Urology and Nephrology Studies
- Bone Tumor Diagnosis and Treatments
- Gallbladder and Bile Duct Disorders
- Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Cancer, Hypoxia, and Metabolism
- Neonatal Health and Biochemistry
- Metabolism and Genetic Disorders
Rigshospitalet
2016-2025
Copenhagen University Hospital
2016-2025
University of Copenhagen
2007-2024
Center for Inherited Blood Disorders
2012
PREAMBLEThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific professional organization founded in 1954 to promote the science, technology, practical application nuclear medicine. The European Association (EANM) a nonprofit medical association 1985 facilitate communication worldwide among individuals pursuing clinical academic excellence SNMMI EANM members are physicians, technologists, scientists specializing research practice medicine.The will...
Abstract Epilepsy is one of the most frequent neurological conditions with an estimated prevalence more than 50 million people worldwide and annual incidence two million. Although pharmacotherapy anti-seizure medication (ASM) treatment choice, ~30% patients epilepsy do not respond to ASM become drug resistant. Focal form epilepsy. In drug-resistant focal epilepsy, surgery a option depending on localisation seizure focus for relief or freedom consecutive improvement in quality life. Beside...
Appropriate imaging is essential in the treatment of children and adolescents with rhabdomyosarcoma. For adequate stratification optimal individualised local utilising surgery radiotherapy, high-quality crucial. The paediatric radiologist, therefore, an member multi-disciplinary team providing clinical care research. This manuscript presents European rhabdomyosarcoma guideline, based on recently developed guideline Paediatric Soft Tissue Sarcoma Study Group (EpSSG) Imaging Committee. was...
Positron emission tomography (PET) has been widely used in paediatric oncology. 2-Deoxy-2-[
Abstract The Society of Nuclear Medicine and Molecular Imaging (SNMMI), founded in 1954, is an international scientific professional organization with a purpose to promote the science, technology, practical application nuclear medicine. European Association (EANM), 1985, nonprofit medical association facilitate communication among individuals medicine pursuing clinical academic excellence. Members SNMMI EANM are physicians, technologists, scientists who specialize research practice will...
Meta-[<sup>123</sup>I]iodobenzylguanidine ([<sup>123</sup>I]MIBG) scintigraphy with SPECT/CT is the standard of care for diagnosing and monitoring neuroblastoma. Replacing [<sup>123</sup>I]MIBG new PET tracer meta-[<sup>18</sup>F]fluorobenzylguanidine ([<sup>18</sup>F]MFBG) further improving sensitivity reducing noise in a long-axial-field-of-view (LAFOV) PET/CT scanner enable increased image quality faster acquisition time, allowing examinations to be performed without sedation or general...
PURPOSE Positron emission tomography (PET) has been used in grading of CNS tumors adults, whereas studies children have limited. PATIENTS AND METHODS Nineteen boys and 19 girls (median age, 8 years) with primary were studied prospectively by fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) PET (n = 16) or without 22) H(2)(15)O-PET before therapy. Image processing included coregistration to magnetic resonance imaging (MRI) all patients. The FDG uptake was semiquantitatively calculated a...
Fabry disease is a rare, multiorgan disease. The most serious complications involve the kidney, brain and heart. This study aims to assess effect of enzyme replacement therapy (ERT) using agalsidase-beta in children with We carried out nationwide, descriptive observational retrospective cohort 10 (9-16 years at baseline), who underwent regular systematic investigations for 1-8 after initiation ERT (Fabryzyme®, Genzyme). Ophthalmological, echocardiographic abnormalities hypohidrosis were...
Complete resection is the treatment of choice for most pediatric brain tumors, but early postoperative MRI detection residual tumor may be misleading because signal changes caused by operation. PET imaging with amino acid tracers in adults increases diagnostic accuracy literature neurooncology limited. A hybrid PET/MRI system highly beneficial children, reducing number scanning procedures, and this to our knowledge first larger study using neurooncology. We evaluated if additional...
Nonpharmacological strategies are increasingly used in pediatric procedures, but MRI, sedation and general anesthesia still commonly required.To evaluate the effectiveness of nonpharmacological interventions reducing use patients undergoing to investigate effects on scan time, image quality, anxiety.We searched Ovid Medline, CINAHL, Embase, CENTRAL from inception through October 10, 2022.We included randomized controlled trials quasi-experimental designs comparing effect a intervention with...
Total-body PET and long-axial-field-of-view (LAFOV) are game-changing innovations at the threshold of clinical implementation. Early experience has demonstrated high sensitivity (84 cps/kBq), a time-of-flight resolution 214 ps, improved image quality enabling ultra-fast or low-dose
Alpha-mannosidosis is an ultra-rare progressive lysosomal storage disorder caused by deficiency of alpha-mannosidase. Timely diagnosis the disease has potential to influence patient outcomes as preventive therapies can be initiated at early stage. However, no internationally-recognised algorithm currently available for disease. With aim developing a diagnostic alpha-mannosidosis international panel experts met reach consensus applying nominal group technique. Two proposals were developed...
Abstract Background Central nervous system (CNS) tumors cause the highest death rates among childhood cancers, and survivors frequently have severe late effects. Magnetic resonance imaging (MRI) is modality of choice, but its specificity can be challenged by treatment-induced signal changes. In adults, O-(2-[18F]fluoroethyl)-l-tyrosine ([18F]FET) PET assist in interpreting MRI findings. We assessed clinical impact diagnostic accuracy adding [18F]FET to children with CNS tumors. Methods A...
Objective Quantification of 18-fluorodeoxyglucose (FDG) uptake in inflamed high-risk carotid atherosclerotic plaques is challenged by the spatial resolution positron emission tomography (PET) and luminal blood activity. Late acquisition protocols have been used to overcome these challenges enhance contrast between plaque blood-pool FDG However, for prospective studies late inconvenient patient staff, most retrospective use data from early protocols. The objective was evaluate changes...