A5101514377- Radioactive element chemistry and processing
- Metal-Organic Frameworks: Synthesis and Applications
- Hepatitis Viruses Studies and Epidemiology
- Covalent Organic Framework Applications
- Viral gastroenteritis research and epidemiology
- Asymmetric Synthesis and Catalysis
- Graphene research and applications
- Chemical Synthesis and Characterization
- Catalytic C–H Functionalization Methods
- Liver Disease and Transplantation
- Fullerene Chemistry and Applications
- Hepatitis B Virus Studies
- Synthetic Organic Chemistry Methods
- Lanthanide and Transition Metal Complexes
- Boron and Carbon Nanomaterials Research
- Cyclopropane Reaction Mechanisms
- Advanced Chemical Physics Studies
- Hepatitis C virus research
- Asymmetric Hydrogenation and Catalysis
- Nanocluster Synthesis and Applications
- Radiation Detection and Scintillator Technologies
- Catalytic Cross-Coupling Reactions
- Luminescence Properties of Advanced Materials
- Oxidative Organic Chemistry Reactions
- Liver Diseases and Immunity
Jiangxi Normal University
2025
Tianjin Medical University
2024-2025
Soochow University
2016-2024
Washington University in St. Louis
2024
Gezhouba Group (China)
2024
Guiyang Medical University
2024
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences
2024
Brown University
2022-2023
John Brown University
2023
Providence College
2022
Effective and selective removal of 99TcO4– from aqueous solution is highly desirable for both waste partitioning contamination remediation purposes in the modern nuclear fuel cycle, but significant challenge. We report here a hydrolytically stable radiation-resistant cationic metal–organic framework (MOF), SCU-101, exhibiting extremely fast kinetics, exceptional distribution coefficient, high sorption capacity toward TcO4–. More importantly, this material can selectively remove TcO4–...
Metal-organic frameworks (MOFs) based on zirconium phosphonates exhibit superior chemical stability suitable for applications under harsh conditions. These compounds mostly exist as poorly crystallized precipitates, and precise structural information has therefore remained elusive. Furthermore, a zero-dimensional phosphonate cluster acting secondary building unit been lacking, leading to poor designability in this system. Herein, we overcome these challenges obtain single crystals of three...
Uranium is not only a strategic resource for the nuclear industry but also global contaminant with high toxicity. Although several strategies have been established detecting uranyl ions in water, searching new uranium sensor material great sensitivity, selectivity, and stability remains challenge. We introduce here hydrolytically stable mesoporous terbium(III)-based MOF compound 1, whose channels are as large 27 Å × 23 equipped abundant exposed Lewis basic sites, luminescence intensity of...
Many environmental pollutants inherently exist in their anionic forms and are therefore highly mobile natural water systems. Cationic framework materials that can capture those desirable but scarcely reported. Here we present a mesoporous cationic thorium-based MOF (SCU-8) containing channels with large inner diameter of 2.2 nm possessing high surface area 1360 m2 g-1. The anion-exchange properties SCU-8 were explored many anions including small oxo like ReO4- Cr2O72- as well organic dyes...
The infection of bacteria and fungus is one the most challenging global threats to human health. With recent advancement in nanoscience nanotechnology, much progress has been achieved development antimicrobial nanomedicine; however, these nanomaterial-based antibacterial agents still suffer from potential biological toxicity, poor degradation, various secondary pollution. Here, we demonstrate fabrication low-toxic degradable carbon dots (CDs) vitamin C by one-step electrochemical method....
Abstract Direct removal of 99 TcO 4 − from the highly acidic solution used nuclear fuel is beneficial for recovery uranium and plutonium more importantly aids in elimination Tc discharge into environment. However, this task represents a huge challenge given combined extreme conditions super acidity, high ionic strength, strong radiation field. Here we overcome using cationic polymeric network with significant uptake capabilities four aspects: fastest sorption kinetics, highest capacity, most...
99 Tc contamination at legacy nuclear sites is a serious and unsolved environmental issue. The selective remediation of TcO4- in the presence large excess NO3- SO42- from natural waste systems represents significant scientific technical challenge, since anions with higher charge density are often preferentially sorbed by traditional anion-exchange materials. We present solution to this challenge based on stable cationic metal-organic framework, SCU-102 (Ni2 (tipm)3 (NO3 )4 ), which exhibits...
99Tc is one of the most problematic fission products in nuclear fuel cycle owing to its large inventory used fuel, long half-life, potential radiation hazard, high environmental mobility major species 99TcO4-, and redox-active nature. Ideally, 99TcO4- should be removed at first stage, when rods are dissolved highly concentrated nitric acid solution, which can substantially reduce interference with solvent extraction process through catalytic redox reactions key actinides diminish chance...
Although comprehensive progress has been made in the area of coordination polymer (CP)/metal–organic framework (MOF)-based proton-conducting materials over past decade, searching for a CP/MOF with stable, intrinsic, high anhydrous proton conductivity that can be directly used as practical electrolyte an intermediate-temperature proton-exchange membrane fuel cell assembly durable power generation remains substantial challenge. Here, we introduce new CP, (NH4)3[Zr(H2/3PO4)3] (ZrP), which...
We report one of the most efficient scavenger materials, a cationic crystalline coordination polymer SBN for trapping ReO4–, surrogate 99TcO4–, as an anionic radioactive contaminant great concern. The uptake capacity ReO4– reaches 786 mg/g, value noticeably higher than state art anion-exchange resins and other inorganic or hybrid anion sorbents. Once being captured, is greatly immobilized, almost no can be eluted using large excess nitrate, carbonate, phosphate anions. processes are featured...
Removal of 99TcO4- from legacy defense nuclear tank waste at Savannah River Site is highly desirable for the purpose safety and environmental protection, but currently not achievable given extreme conditions including high alkalinity, ionic strength, strong radiation field. Herein, we present a potential solution to this long-term issue by developing two-dimensional cationic metal organic framework SCU-103, showing ultrahigh stability in alkaline aqueous media great resistance both β γ...
Abstract Searching for actinide decorporation agents with advantages of high efficiency, minimal biological toxicity, and oral efficiency is crucial nuclear safety the sustainable development energy. Removing actinides deposited in bones after intake one most significant challenges remaining this field because instantaneous formation highly stable phosphate complexes upon contact hydroxyapatite. Here we report a hydroxypyridinone-based ligand (5LIO-1-Cm-3,2-HOPO) exhibiting stronger affinity...
Crystalline porous materials such as covalent organic frameworks (COFs) are advanced to tackle challenges of catalysis and separation in industrial processes. Their synthetic routes often require elevated temperatures, closed systems with high pressure, long reaction times, hampering their applications. Here we use a traditionally unperceived strategy assemble highly crystalline COFs by electron beam irradiation controlled received dosage, contrasting sharply the previous observation that...
Direct removal of 99TcO4– from alkaline nuclear waste is desirable because the management and environmental protection relevant to energy but yet be achieved given that combined features decent base-resistance high uptake selectivity toward anions with low charge density have not been integrated into a single anion-exchange material. Herein, we proposed strategy overcoming these challenges by rationally modifying imidazolium unit cationic polymeric network (SCU-CPN-4) bulky alkyl groups...
Luminescent covalent organic frameworks (LCOFs) have emerged as indispensable candidates in various applications due to their greater tunable emitting properties and structural robustness compared small molecule emitters. An unsolved issue this area is developing highly luminescent LCOFs of which the nonradiative quenching pathways were suppressed much possible. Here, a robust aminal-linked COF (DD-COF) possessing perdeuterated light-emitting monomers was designed synthesized. The...
The first catalytic asymmetric cross-coupling of α-halo carbonyl compounds with aryl metal reagents has been developed, thereby generating synthetically useful α-aryl carboxylic acid derivatives in good enantiomeric excess. method can also be applied to enantioselective alkenylation reactions.
The total synthesis of (−)-colombiasin A (2) and (−)-elisapterosin B (3) has been achieved. key step is a C−H functionalization process, the combined activation/Cope rearrangement, between methyl (E)-2-diazo-3-pentenoate 1-methyl-1,2-dihydronaphthalenes. When reaction catalyzed by dirhodium tetrakis((R)-(N-dodecylbenzenesulfonyl)prolinate), Rh2(R-DOSP)4, an enantiomer differentiation occurs where one dihydronaphthalene undergoes rearrangement while other cyclopropanation. This sequence...
Abstract Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim explore the prevalence clinical diagnosed AD children aged 1–7 ys Twelve metropolises were chosen from different areas In each region, we selected 4–10 kindergartens and 2–5 vaccination clinics randomly. A complete history-taking skin examination performed by dermatologists. The definite diagnosis severity determined two or three All criteria...
Leucine-rich repeat kinase 2 (LRRK2) is a large, multidomain protein which contains domain and GTPase among other regions. Individuals possessing gain of function mutations in the such as most prevalent G2019S mutation have been associated with an increased risk for development Parkinson's disease (PD). Given this genetic validation inhibition LRRK2 activity potential means affecting progression, our team set out to develop inhibitors test hypothesis. A high throughput screen compound...