A5059556661- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Intraoperative Neuromonitoring and Anesthetic Effects
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Spinal Fractures and Fixation Techniques
- Neonatal and fetal brain pathology
- Intensive Care Unit Cognitive Disorders
- Nerve Injury and Rehabilitation
- Spinal Cord Injury Research
- Long-Term Effects of COVID-19
- Neuroscience and Neural Engineering
- Anesthesia and Pain Management
- Diet and metabolism studies
- Patient-Provider Communication in Healthcare
- Spine and Intervertebral Disc Pathology
- Transcranial Magnetic Stimulation Studies
- Cerebrovascular and Carotid Artery Diseases
- Neural dynamics and brain function
- Scoliosis diagnosis and treatment
- Anesthesia and Sedative Agents
- Mosquito-borne diseases and control
- Decision-Making and Behavioral Economics
- Cytomegalovirus and herpesvirus research
- Neurological and metabolic disorders
Columbia University Irving Medical Center
2018-2024
Columbia University
2003-2022
NewYork–Presbyterian Hospital
2017-2020
The Neurological Institute
2005
Wake Forest University
2002
To examine the seizure trajectories of adults with epilepsy developing drug-resistant (DRE) and to identify predictors trajectory outcome.Adult patients failing two antiepileptic drugs (AEDs) due inefficacy starting their third AED at a tertiary center were followed for outcome during medical management. Seizure categorized into one four patterns: (1) course constant seizures; (2) fluctuating course; (3) delayed attainment freedom (seizure >12 months after start study, but patient stayed in...
Summary Objective The dynamics of the postictal period, which may demonstrate such dramatic clinical phenomena as focal neurological deficits, prolonged coma and immobility, even sudden death, are poorly understood. We sought to classify characterize phases bilateral tonic–clonic seizures based on electroencephalographic (EEG) criteria associated features. Methods performed a detailed electroclinical evaluation period in series 31 16 patients undergoing epilepsy surgery evaluations for...
ABSTRACT Epilepsy is a chronic disorder that has been associated with other specific health problems. Evidence from recent clinical and basic investigations indicates aspects of cerebral dysfunction lowered seizure threshold may also predispose toward disorders such as depression, cognitive impairment, sleep disorders, migraine. Similarly, certain types brain injury increase the risk adverse antiepileptic drug (AED) effects. For example, history febrile seizures three fold in occurrence...
Introduction: EEG monitoring is a critical tool for identifying cerebral ischemia during carotid endarterectomy (CEA). Quantitative can be used to supplement visual review, but which measures best predict post-clamp unclear. Purpose: To determine quantitative parameters reliably detect intraoperative CEA. Methods: The authors identified patients who underwent at Columbia University Medical Center from 2007 2014 with monitoring. Two masked physicians reviewed these EEGs retrospectively and...
Purpose: Spatial patterns of long-range seizure propagation in epileptic networks have not been well characterized. Here, we use ictal high-gamma activity (HGA) as a proxy intense neuronal population firing to map the spatial evolution recruitment. Methods: Ictal HGA (80–150 Hz) was analyzed 13 patients with 72 seizures recorded by stereotactic depth electrodes, using previously validated methods. Distinct clusters channels signature were identified, and hubs defined stereotypically...
Although epidural stimulation of the lumbar spinal cord has emerged as a powerful modality for recovery movement, how it should be targeted to cervical activate arm and hand muscles is not well understood, particularly in humans. We sought map muscle responses posterior hypothesized that lateral over dorsal root entry zone would most effective strongest innervated by stimulated segment. Twenty-six people undergoing clinically indicated spine surgery consented mapping motor responses. During...
Objective: The objective of our study is to determine if use a mobile tutorial EEG atlas will improve user recognition waveforms and patterns. Background: According the ACGME, every graduating neurology resident must be proficient at interpreting an electroencephalogram (EEG). interpretation exercise in visual analysis pattern recognition. As such, mastery requires exposure large volume varied cases. Traditional methods teaching include: (1) books/lectures, which usually do not provide...
We plan to evaluate whether quantitative electroencephalography (QEEG) can be used bolster detection of ischemic change during carotid endarterectomy.
Abstract Objective Characterization of progressive multi-site seizure recruitment using high frequency oscillations. Methods Ictal and interictal oscillations were identified in a series 13 patients with 72 seizures recorded by stereotactic depth electrodes, previously validated methods. Channels ictal assigned to distinct spatial clusters, hubs stereotypically recruited non-overlapping clusters. Clusters correlated asynchronous terminations provide supportive evidence for independent...