- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- 3D Printing in Biomedical Research
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Graphene and Nanomaterials Applications
- Temporomandibular Joint Disorders
- Cleft Lip and Palate Research
- Bone and Dental Protein Studies
- Metal Extraction and Bioleaching
- Dental materials and restorations
- Craniofacial Disorders and Treatments
- Osteoarthritis Treatment and Mechanisms
- Wound Healing and Treatments
- Orthopaedic implants and arthroplasty
- Carbon Nanotubes in Composites
- Bone Metabolism and Diseases
- Higher Education and Sustainability
- Knowledge Societies in the 21st Century
- Oral and Maxillofacial Pathology
- Engineering and Information Technology
- Orthodontics and Dentofacial Orthopedics
- Advanced Drug Delivery Systems
- Hydrogels: synthesis, properties, applications
Universidad Nacional Autónoma de México
2016-2023
Secretaría de Investigación, Innovación y Educación Superior
2022
Autonomous University of Tlaxcala
2019-2020
Autonomous University of San Luis Potosí
2009-2017
Neovascularization over dental implants is an imperative requisite to achieve successful osseointegration onto implanted materials. The aim of this study was investigate the effects on in vitro angiogenesis anodized 70 nm diameter TiO2 nanotubes (NTs) Ti6Al4V alloy synthesized and disinfected by means a novel, facile, antibacterial cost-effective method using super oxidized water (SOW). We also evaluated role surface roughness chemical composition materials angiogenesis.The commercially pure...
Articular cartilage is a specialized tissue that provides smooth surface for joint movement and load transmission. Unfortunately, it has limited regenerative capacity. Tissue engineering, combining different cell types, scaffolds, growth factors, physical stimulation become an alternative repairing regenerating articular cartilage. Dental Follicle Mesenchymal Stem Cells (DFMSCs) are attractive candidates engineering because of their ability to differentiate into chondrocytes, on the other...
Strontium folate (SrFO) is a recently developed bone promoting agent with interest in medical and pharmaceutical fields due to its improved features comparison current strontium based therapies for osteoporosis other diseases. In this work SrFO derivative was synthesized loaded into biohybrid scaffolds obtained through lyophilisation of semi-interpenetrating networks chitosan polyethylene glycol dimethacrylate beta tri-calcium phosphate (βTCP) fabricated using free radical polymerization....
The search of suitable combinations stem cells, biomaterials and scaffolds manufacturing methods have become a major focus research for bone engineering. aim this study was to test the potential dental pulp cells attach, proliferate, mineralize differentiate on 3D printed polycaprolactone (PCL) scaffolds. A 100% pure Mw: 84,500 ± 1000 PCL selected. 5 × 10 mm3 parallelepiped were designed as wood-pilled structure composed 20 layers 250 μm in height, non-alternate order ([0,0,0,90,90,90°])....
Bone Regeneration represents a clinical need, related to bone defects such as congenital anomalies, trauma with loss, and/or some pathologies cysts or tumors This is why polymeric biomaterial that mimics the osteogenic composition and structure high potential face this problem. The method of obtaining these materials was first prepare stabilized hydrogel by means physical bonds then make use lyophilization technique obtain 3D porous scaffolds temperature conditions -58 °C pressure 1 Pa for...
Abstract The present work studies the effect of Mn doping on crystalline structure Hap synthesized by hydrothermal method at 200 °C for 24 h, from Ca(OH) 2 and (NH 4 ) HPO , incorporating MnCl to 0.1, 0.5, 1.0, 1.5 2.0 %wt concentrations. Samples were characterized X-Ray Diffraction technique, which revealed diffraction peaks that corresponded hexagonal monoclinic phase Hap; it was observed average size crystallite decreased 23.67 22.69 nm as concentration increased. TEM shows in all...
In craniofacial tissue regeneration, the current gold standard treatment is autologous bone grafting, however, it presents some disadvantages. Although new alternatives have emerged there still an urgent demand of biodegradable scaffolds to act as extracellular matrix in regeneration process. A potentially useful element strontium. It known promote stimulation osteoblasts while inhibiting osteoclasts resorption, leading neoformed bone. The present paper reports preparation and...
Today, regenerative osteogenesis represents a clinical need, due to the incidence of bone defects that involve groups pathologies ranging from congenital anomalies traumatic injuries, as well problems presented surgically. This is why design polymeric biomaterial (scaffold) chitosan, carboxymethylcellulose, zinc oxide, and calcium carbonate with similar characteristics in terms composition structure offers high potential help address this health problem. The technique for obtaining scaffolds...
Interpenetrating polymer network are a combination of two or more polymers that allow creating new material with unique set properties. An ideal scaffold for an extracellular matrix could be achieved by the to improve scaffold’s physical and chemical characteristics. The aim this work was synthesize characterize interpenetrating polyvinylpyrrolidone poly(acrylic acid) in contact cells oral mucosa. A sequential synthesis method performed, adding xerogel acrylic acid monomer. Infrared...
Abstract Fiber scaffolds are attractive materials for mimicking, within a 3D in vitro system, any living environment which animal cells can adhere and proliferate. In three dimensions, have the ability to communicate organize into complex architectures similar those found their natural environments. The aim of this study was evaluate, terms cell reactivity, new model: dental pulp stem (DPSCs) polymeric textile. Scaffolds were knitted from polyglycolic acid (PGA) or polydioxanone (PDO) fibers...
The aim of this study was to obtain autologous dermal-epidermal skin substitutes from oral mucosa diabetic subjects as a first step towards possible clinical application for cases foot.Oral obtained and healthy (n=20 per group). Epidermal cells were isolated cultured using fibrin develop in vitro by the air-liquid technique with human serum supplement media. Substitutes immunocharacterized collagen IV cytokeratin 5-14 specific markers. A Student´s t- test performed assess differences between...
Polyglycerol sebacate (PGS) scaffolds obtained using a leaching technique were modified with iodine-doped polypyrrole (PPy-I) in plasma reactor order to study the effect of exposure time on cell viability hDPSCs. SEM analysis showed formation and growth PPy-I particles as was increased, while FTIR XPS revealed presence -NH- N+ groups chemical composition surfaces, relating increase amount PPY-I particles. The water contact angle measurements an scaffold’s hydrophilicity greater times which...
Enamel Matrix Derivative (EMD) is a rich amelogenin and amelin biomaterial that has been demonstrated to induce reparative process similar normal odontogenesis when placed in contact with pulp tissue. However, its effects capping on primary teeth not previously reported. The aim of the present case report favorable clinical radiographic findings molar treated direct (DPC) using EMD as material 6-year-old girl. Results: After 12 months, there was no sign or symptom indicative treatment...
Jarosite-type compounds precipitated in the zinc industry for iron control can also incorporate arsenic and be used wastewater treatment As elimination. According with last, this work is related to incorporation at room temperature decomposed potassium jarosite. The began synthesis of compound 75 °C 9 h using Fe2(SO4)3 K2SO4 a pH 1.1. Once jarosite was obtained, solids were subjected an alkaline decomposition NaOH 10 30 min, then added solution as HAsNaO4 modified by adding HNO3 until it...
The objective of this work was the preparation and evaluation a bioresorbable bilayered system for application in treatment dermal lesions. based on polyesterurethane as external layer gelatin membrane internal layer. synthesized from poly(ε-caprolactone), polyethylene glycol 1 or 10 kDa hydrophilic component Pluronic F127 an amphiphilic l-lysine ethyl ester diisocyanate urethane precursor. Gelatin obtained by crosslinking with naturally occurring crosslinker genipin. Three important points...
For decades, jarosites have been precipitated by controlling Fe in hydrometallurgical circuits. In addition, their synthesis, characterization, precious metals incorporation, decomposition and leaching led to important results this field. Nowadays, new topics related the synthesis of these compounds directed studies for applications such as lithium-ion batteries (as cathodes or/and anodes). Additionally, work, evaluation kinds biomaterials be used bone tissue engineering is shown, which a...
This cross-sectional study aimed to establish a relationship between the Normative Need for Orthodontic Treatment (NNOT) and oral health among Mexican adolescents aged 13-15 years old. A convenience sample of 424 subjects in Mexico City participated study. The dependent variable used was NNOT, which determined via dental component (grades 4 5) Index (IOTN). variables were as follows: caries experience, hygiene, self-reported temporomandibular joint pain, bruxism. Logistic regression models...
Abstract Electrospun scaffolds with diameter fibers compared to those in the extracellular matrix were produced poly(lactic acid) (PLA) and non-denatured collagen from bovine dentin (DCol). DCol was obtained through an improved version of Longin method by acid erosion hydroxyapatite roots teeth a 2-year-old cattle. The characterized energy dispersive X-ray spectroscopy (EDS), carbon, nitrogen, oxygen found be main elements protein. Infrared analysis revealed typical bands at about 3300,...
Temporomandibular joint (TMJ) is sensitive to loading and mechanical stress that provokes morphological changes produced by the impact in occlusal plane. Here, this evaluated TMJ articular disc cartilage using an vivo model of unilateral plane analysis serial tissue sections stained with Hematoxylin-Eosin (H-E) or Masson trichrome technique. Thus, six groups 5 Wistar rats (200 - 250 g) are subjected biomechanical dental stimulation placing resin interference, tooth wear made upper left...