- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Organ Donation and Transplantation
- Congenital Anomalies and Fetal Surgery
- Organ and Tissue Transplantation Research
- Ureteral procedures and complications
- Pharmacological Effects and Toxicity Studies
- Diphtheria, Corynebacterium, and Tetanus
- Pediatric Hepatobiliary Diseases and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Neurological Complications and Syndromes
- Clinical Nutrition and Gastroenterology
- Urological Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Transplantation: Methods and Outcomes
- Clostridium difficile and Clostridium perfringens research
- Liver Disease Diagnosis and Treatment
- Abdominal Trauma and Injuries
Koç University
2024
University of Wisconsin–Madison
1988-2007
UW Health University Hospital
1990-1997
We studied multiple determinants of graft survival at a single center and the effects nonimmunologic loss on transplant survival. This retrospective study examined results 589 cadaver donor transplants performed between 1986 1992. Graft rates were calculated using Kaplan-Meier estimates for both overall (all causes loss) immunologic (function lost due to acute or chronic rejection noncompliance). Cadaver was significantly poorer with an increasing degree DR mismatch (P=0.02). An analysis...
The development of the University Wisconsin (UW) cold storage solution has extended safe preservation liver and pancreas from 6 to 24 hours or more. From May 1987 until November 1991, 288 livers 163 simultaneous pancreas/kidney transplants were performed using UW solution. mean times were: liver, 12.7 +/- 4.4 hours, 17.2 kidney, 19.2 4.3 hours. Included in this series 35 reduced-sized transplants, 7 cluster 132 combined liver/pancreas retrievals. No differences allograft function...
The results of kidney retransplantation in the cyclosporine era remain to be determined. Over a 42-month period, 76 nonprimary renal transplants (66 second, 7 third, 3 fourth allografts) were performed 73 recipients under immunosuppression. patient population was predominantly white (90.4%) with mean age 32.3 years. Twenty-one (28.8%) diabetic, and 36 (49.3%) highly sensitized (panel-reactive antibody [PRA] greater than 50%). Sixty-two patients received cadaver donor grafts while remaining...
Since the introduction of OKT3 at our center in January 1986, we have performed 246 cadaveric renal transplants (220 primary, 26 nonprimary). All patients received quadruple immunosuppression consisting prednisone, azathioprine, and sequential use Minnesota antilymphoblast globulin (MALG) cyclosporine. (Orthoclone OKT3) therapy was reserved for corticosteroid- and/or ALG-resistant rejection. Of patients, 138 developed one or more rejection episodes (56.1%). Ninety-seven (70.3%) were...
The efficacy of RS-61443 and cyclosporine utilized either alone or in combination was assessed both a segmental heterotopic total orthotopic canine intestinal transplant model. Twenty-eight dogs underwent (150-cm) transplants five transplants. Five groups were compared: group 1, no immunosuppression; 2, prednisone; 3, RS-61443, 4, 5, subtherapeutic cyclosporine. Group 3 animals achieved median survival 136 days, while the survivals 5 < = 10 days (P .001). Twenty deaths 1 through secondary to...
Excorine drainage of the pancreas into bladder has become most frequently used exocrine procedure after transplantation since we described this technique in 1982. The advantages are technical simplicity associated with a low infection rate and incidence surgical complication. Selected centers around world have reported 1‐year graft survival exceeding 80% use drainage. Disadvantages include urinary problems such as hematuria, dyauria, tract infections. number using preferred steadily...
A 9-year-old boy presented with rectal impalement injury associated through-and-through bladder rupture and intraperitoneal communication. We believe this to be the first reported case of causing an rupture.
Abstract Clostridial infection of a liver transplant is reported and was treated successfully with immediate retransplantation antibiotics. This strategy may salvage patients who otherwise have fulminant course certain death. case supports the general principle that localized to can be when appropriate.
Living donor liver transplantation is an important treatment option in countries like ours where cadaver donors are insufficient. This surgery a major operation for the as well recipient. We should minimize damage to who come organ donation healthy way and risks of such surgery. For this purpose, we have explained details first laparoscopic hepatectomy performed our country.