Liang Li

ORCID: 0000-0003-0799-2885
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Enhanced Recovery After Surgery
  • Venous Thromboembolism Diagnosis and Management
  • Acupuncture Treatment Research Studies
  • Medical Imaging and Analysis
  • Central Venous Catheters and Hemodialysis
  • Pelvic and Acetabular Injuries
  • Anesthesia and Sedative Agents
  • Tuberculosis Research and Epidemiology
  • Cervical and Thoracic Myelopathy
  • Atrial Fibrillation Management and Outcomes
  • Hernia repair and management
  • Hip and Femur Fractures
  • Infectious Diseases and Tuberculosis
  • Nerve injury and regeneration
  • Pregnancy-related medical research
  • Scoliosis diagnosis and treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Clinical practice guidelines implementation
  • Reconstructive Surgery and Microvascular Techniques
  • Healthcare and Venom Research
  • Myofascial pain diagnosis and treatment

Baoding People's Hospital
2025

Dongyang People's Hospital
2013-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2010-2025

Wenzhou Medical University
2013-2025

Zhongda Hospital Southeast University
2023-2024

Shandong Provincial Hospital
2023-2024

Chinese People's Liberation Army
2024

Public Health Clinical Center of Chengdu
2024

Union Hospital
2024

Jilin University
2024

Angiotensin-converting enzyme (ACE), an important part of the renin-angiotensin system, is implicated in stimulating fibrotic processes heart, lung, liver and kidney, while ACE inhibitor (ACEI) promotes physiological tissue repair these organs. The mechanism closely related to TGF-β1 pathways. However, reported effects applying ACEIs during scar formation are unclear. Hence, we explored anti-fibrotic ACEI molecular mechanisms involved a mouse model.After full-thickness skin wound operation,...

10.1111/bph.14489 article EN British Journal of Pharmacology 2018-08-30

// Liang Li 1, * , Juying Jin Su Min 1 Dan Liu and Ling Department of Anesthesiology, The First Affiliated Hospital Chongqing Medical University, Chongqing, China These authors have contributed equally to this work Correspondence to: Min, email: minsu1068@163.com Keywords: enhanced recovery after surgery, colorectal cancer, compliance, prognosis Received: April 18, 2017 Accepted: May 23, Published: June 22, ABSTRACT We explored the effects different levels compliance with an surgery (ERAS)...

10.18632/oncotarget.18602 article EN Oncotarget 2017-06-22

Postoperative delirium (POD) is a prevalent complication, particularly in elderly patients with hip fractures (HFs). It significantly affects recovery, length of hospital stay, healthcare costs, and long-term outcomes. Existing studies have investigated risk factors for POD, but most are limited by single-factor analyses or small sample sizes. This study systematically determines independent using large-scale data machine learning techniques develops validated nomogram model to support early...

10.5498/wjp.v15.i3.102117 article EN World Journal of Psychiatry 2025-02-26

To observe the analgesic effect of electroacupuncture (EA) at different intensities on visceral pain in rats and explore supraspinal central mechanism dose-response relationship. Male SD were randomly divided into a normal group, model group groups EA (0.5, 1, 2, 3 6 mA, rats/group). The rat was established using mustard oil enema. Abdominal rectus electromyography (EMG) used to motor response rats. A colorectal distension (CRD) 60 mm Hg adopted induce abdominal muscle discharge for 20 s...

10.13702/j.1000-0607.20241090 article EN PubMed 2025-03-25

The clinical application of small interfering RNA (siRNA) drugs provides promising opportunities to develop treatment strategies for autoimmune inflammatory diseases. In this study, siRNAs targeting the endoplasmic reticulum nucleus signaling 1 (ERN1) gene (siERN1) were screened. Two cationic polymers, polyethylenimine (PEI) and poly(β-amino amine) (PBAA), which can improve efficiency siRNA transfection, used as siERN1 delivery carriers. They implemented construct a nanodrug system with...

10.1021/acsnano.1c03726 article EN ACS Nano 2021-09-29

Background The quality of reporting in systematic reviews (SRs)/meta-analyses (MAs) diagnostic tests published by authors China has not been evaluated. aims present study are to evaluate the SRs/MAs using PRISMA statement and determine changes over time. Methods According inclusion exclusion criteria, we searched five databases including Chinese Biomedical Literature Database, PubMed, EMBASE, Cochrane Library, Web knowledge, identify on tests. searches were conducted July 14, 2012 cut off...

10.1371/journal.pone.0085908 article EN cc-by PLoS ONE 2014-01-21

Progranulin (PGRN) is a multifunctional growth factor involved in many physiological processes and disease states. The apparent protective role of PGRN the importance chondrocyte autophagic function progression osteoarthritis (OA) led us to investigate regulation autophagy. knockout chondrocytes exhibited deficient response with limited induction following rapamycin, serum starvation, IL-1β-induced PGRN-mediated anabolism suppression catabolism were largely abrogated presence BafA1 autophagy...

10.1016/j.gendis.2022.05.031 article EN cc-by-nc-nd Genes & Diseases 2022-06-13

Retrospective study.To explore a relation between somatosensory- and motor-evoked potential (SEPs, MEPs) corresponding thoracic cord function for spinal decompression surgery (TSDS) in patients with neurological deficit.Although SEPs MEPs monitoring has been developed as an essential technique surgery. There are limited data on the reliability of using TSDS its prognosis.One hundred twenty underwent our hospital, 91 completed trial. All were divided into three subgroups according to changes...

10.1097/brs.0000000000003989 article EN Spine 2021-02-15

To evaluate the safety and efficacy of pharmacomechanical thrombolysis (PMT) performed for patients with relative contraindications.From June 2014 to December 2016, 112 acute or subacute proximal deep vein thrombosis (DVT) were enrolled in this study. 60 (including 27 DVT 33 patients) treated catheter-directed (CDT), 52 contraindications 25 PMT. Assessment venous recanalization was conducted using venography time Inferior vena cava filter is removed, complications used compare between...

10.1097/md.0000000000013013 article EN cc-by-nc Medicine 2018-10-01

Purpose To explore the risk factors of failure for modified single-session Angiojet rheolytic thrombectomy combined with directed iliac vein stenting, filter retrieval in treatment compression iliofemoral thrombosis. Methods During September 2017 to 2021, 278 patients DVT were retrospectively analyzed and 203 eligible inclusion. All tried take treatment. The perioperative between groups: group 1—modified therapy succeed, 2—modified failed. high evaluated by logistic regression analysis....

10.1177/02683555221149587 article EN Phlebology The Journal of Venous Disease 2023-01-06

To study the effects of different acupuncture stimulation on nitric oxide (NO) content in acupoint areas. The experiment was performed 47 healthy volunteers providing informed consents. Both males and females were included each group: 11 cases electro-acupuncture group, 13 manual-acupuncture 16 warm-moxibustion 7 control group. Stimulations given at Jianshi (PC 5) Pericardium Meridian Chengshan (BL 57) Bladder with manual-acupuncture, respectively. NO collected from Ximen 4) Chengjin 56)...

10.1016/s0254-6272(10)60008-8 article EN cc-by-nc-nd Deleted Journal 2010-03-01

OBJECTIVE Human acellular nerve allograft applications have increased in clinical practice, but no studies quantified their influence on reconstruction outcomes for high-level, greater, and mixed nerves, especially the brachial plexus. The authors investigated functional of human gaps patients with plexus injury (BPI) undergoing contralateral C7 (CC7) root transfer to innervate upper trunk, they determined independent predictors recovery shoulder abduction elbow flexion. METHODS Forty-five...

10.3171/2019.2.jns182620 article EN Journal of neurosurgery 2019-04-27
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