A5101712751- Obesity, Physical Activity, Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Nutritional Studies and Diet
- Automotive and Human Injury Biomechanics
- Dementia and Cognitive Impairment Research
- Genetic Associations and Epidemiology
- interferon and immune responses
- Inflammasome and immune disorders
- Tryptophan and brain disorders
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Echinoderm biology and ecology
- Ginseng Biological Effects and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Telomeres, Telomerase, and Senescence
- Tendon Structure and Treatment
- Transportation Safety and Impact Analysis
- Immune Cell Function and Interaction
- Traffic and Road Safety
- Health disparities and outcomes
- Congenital limb and hand anomalies
- Aging and Gerontology Research
- Protist diversity and phylogeny
Jilin University
2013-2022
Jilin Medical University
2022
Tianjin Medical University
2021
University at Buffalo, State University of New York
2021
First Hospital of Jilin University
2017
State Key Laboratory of Automotive Simulation and Control
2015
Zhejiang University
2014
Carbon tetrachloride (CCl4)-induced lipid peroxidation associated with hepatic oxidative stress and cell death is an important mechanism of acute liver injury (ALI). Ginsenoside Rd considered active ingredient ginseng. Evidence suggests that ginsenoside may improve ischaemic stroke, nerve damage, cancer other diseases involving apoptosis, inflammation, stress, mitochondrial autophagy. However, the effects on CCl4-induced ALI its underlying mechanisms are still unclear. In this study, 0.25%...
Background: Prehypertension is a category between normotension and hypertension that becoming increasingly common in China. However, limited data are available on the prevalence correlates of prehypertension northeastern Methods: A cross-sectional study using stratified, clustered multistage, random sampling methods was performed 17,584 participants. Results: The 36.0% 30.8% China, respectively. As age increased, males declined (p-trend < 0.001), parallel to an increase 0.001). for...
There is evidence that body mass index (BMI) closely related to hyperlipidemia. This study aimed estimate the cross-sectional relationship between Body Mass Index and hyperlipidemia.We recruited 21,435 subjects (aged 18-79 years residing in Jilin province, China) using multistage stratified cluster random sampling method. Subjects were interviewed with a standardized questionnaire physically examined. We analyzed BMI hyperlipidemia.The prevalence of hyperlipidemia was 51.09% (52.04% male...
Objective The present study investigated the prevalence and risk factors for Metabolic syndrome. We evaluated association between single nucleotide polymorphisms (SNPs) in apolipoprotein APOA1/C3/A4/A5 gene cluster MetS analyzed interactions of environmental with MetS. Methods A on was conducted using data from a large cross-sectional survey representative population Jilin Province situated northeastern China. total 16,831 participations were randomly chosen by multistage stratified sampling...
Background: Sleep-related breathing disorders (SRBD) have been identified as a major public health problem closely related to adolescent obesity. We aimed estimate the prevalences of SRBD and snoring in adolescents Changchun City, Northeastern China, evaluate associated factors this population. Methods: In total, 1955 aged 11–18 years were recruited City using stratified cluster sampling. Parents caretakers children completed questionnaires, which included demographic characteristics,...
A high body mass index (BMI) is a major risk factor for diabetes, although little known about the characterization of dose-response association adjusted potential confounders. This cross-sectional study was conducted from June 2012 to August 2012; total 21 435 inhabitants in Jilin Province aged between 18 and 79 years were selected randomly based on multistage, stratified cluster sampling. The estimated prevalence diabetes 9.1% overall, 9.4% males 8.9% females. After adjusting confounders,...
Panax ginseng polysaccharides (GPS) are isolated from C. A. Meyer, which has many pharmacological activities. However, although the protective effect of GPS on inflammatory bowel disease (IBD) been characterized, its mechanism not yet fully elucidated. In present study, we clarified it IBD in mice and studied reducing inflammation. model was established by administrating dextran sulfate sodium (DSS) drinking water for 7 days. Our results showed that treatment significantly relieved activity...
Our previous studies using the mass spectrum analysis provided evidence that fibrinopeptide A (FPA) could be a potential biomarker for schizophrenia diagnosis. We sought further to demonstrate variants in fibrinogen alpha chain gene (FGA) coded FPA might confer vulnerability schizophrenia. 1,145 patients with and 1,016 healthy volunteers from Han population Northeast China were recruited. The association of three tag single nucleotide polymorphisms (SNPs) (rs2070011 <mml:math...
This paper presents a trapezoid method for occupant restraint system design analysis based on ride-down energy control theory. The sub-system characteristic determination of an could be simplified and analysed by two-step curve which is generated from method. parameter definitions resulted the target residual some case studies were put into numerical model validation. Occupant responses showed very good agreements between outcomes both simulation. In concept phase, this used to give rapid...
Previous studies have demonstrated a link between depressive symptoms and incidence of mild cognitive impairment (MCI) dementia. Apathy is common neuropsychiatric symptom in MCI dementia but not well characterized as marker for risk decline. Further, the impact depression treatment on has only recently begun to receive attention. This study examines relationship depression, apathy pharmacological sample mid- late-life participants assessed cognitively normal at baseline. Depressive...
Previous studies of race/ethnic differences in depression and apathy, among cognitively normal impaired older adults, have produced mixed results. Two widely used tools are: 1) Geriatric Depression Scale (GDS-15), a self-report assessment depressive symptoms, 2) Neuropsychiatric Inventory Questionnaire (NPI-Q), an informant-rated measure neuropsychiatric symptoms. This study examined the prevalence apathy by race/ethnicity, across clinical status groups, compared rates approach. We conducted...
Ethnopharmacological significance: Panax ginseng C.A.Mey. is a valuable herb as an 'alternative' medicine for the prevention and treatment of liver disease. has been used in many traditional remedies disease monarch or guide medicine. The liver-nourishing liver-protecting activities ginsenoside Rd reported. But protective mechanisms against chemical injury have not fully elucidated. In this study, effects were investigated CCl4-induced mouse model acute (ALI).Aim study: This research to...
Abstract DNA oxidative damage can cause telomere attrition or dysfunction that triggers cell senescence and apoptosis. The hypothesis of this study is folic acid decreases apoptosis in neural stem cells (NSCs) by preventing stress-induced attrition. Primary cultures NSCs were incubated for 9 days with various concentrations (0 - 40 µM ) then 24 h a combination an oxidant (100 hydrogen peroxide, H 2 O ), antioxidant (10 mM N-acetyl-L-cysteine, NAC) vehicle. Intracellular folate concentration,...