A5074703787- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Hearing Loss and Rehabilitation
- Congenital Heart Disease Studies
- Blind Source Separation Techniques
- Energy Harvesting in Wireless Networks
- Marine Bivalve and Aquaculture Studies
- Wireless Body Area Networks
- Wireless Power Transfer Systems
- Analog and Mixed-Signal Circuit Design
- Cardiac Ischemia and Reperfusion
- Retinal Diseases and Treatments
- Speech and Audio Processing
- Ocular Diseases and Behçet’s Syndrome
- Marine and fisheries research
- Radio Frequency Integrated Circuit Design
- Marine Biology and Ecology Research
- Congenital heart defects research
- Mechanical Circulatory Support Devices
- Fish Biology and Ecology Studies
- Advanced Memory and Neural Computing
- Cardiac Structural Anomalies and Repair
- Ocular Infections and Treatments
University of Sousse
2022-2024
University of Bristol
2015-2024
Hôpital Farhat Hached
2018-2024
University of Sfax
2012-2024
Hôpital Sahloul
2022-2024
NIHR Bristol Cardiovascular Biomedical Research Unit
2011-2023
Hopital Universitaire Habib Bourguiba
2017-2023
Hospital Fatuma Bourguiba Monastir
2023
Bristol Royal Infirmary
2003-2023
National Engineering School of Tunis
2010-2022
Background Living grafts produced by combining autologous heart‐resident stem/progenitor cells and tissue engineering could provide a new therapeutic option for definitive correction of congenital heart disease. The aim the study was to investigate antigenic profile, expansion/differentiation capacity, paracrine activity, pro‐angiogenic potential cardiac pericytes assess their engrafting capacity in clinically certified prosthetic grafts. Methods Results CD 34 pos cells, negative endothelial...
ObjectiveSingle-ventricle patients undergoing pediatric heart surgery are a high-risk group owing to reoxygenation injury during cardiopulmonary bypass (CPB). The present study investigated the effects of controlled CPB on biomarkers organ damage, inflammation, stress, and long-term functional outcomes in cyanotic with either single or double ventricle open surgery.MethodsCyanotic (n = 32) 47) surgical correction were randomized receive using standard oxygen levels reoxygenation. markers...
Since being first detected in China, coronavirus disease 2019 (COVID-19) has spread rapidly across the world, triggering a global pandemic with no viable cure sight. As result, national responses have focused on effective minimization of spread. Border control measures and travel restrictions been implemented number countries to limit import export virus. The detection COVID-19 is key task for physicians. erroneous results early laboratory tests their delays led researchers focus different...
Motor imagery (MI) signals recorded by electroencephalography provide the most practical basis for conceiving brain-computer interfaces (BCI). These offer a high degree of freedom. This helps people with motor disabilities communicate device tackling sequence tasks. However, extracting user-specific features and increasing accuracy classifier remain as difficult tasks in MI-based BCI. In this work, we propose new method using artificial neural network (ANN) enhancing performance...
Physiological activation of the hypothalamo-neurohypophyseal system (HNS) by dehydration results is a massive release vasopressin (VP) from posterior pituitary. This accompanied functional remodeling HNS. In this study we used cDNA arrays in an attempt to identify genes that exhibit differential expression hypothalamus following dehydration. Our revealed nine candidate genes, including interleukin-6 (IL-6) as putative novel secretory product HNS worthy further analysis. situ hybridization...
Abstract The availability of grafts to replace small‐diameter arteries remains an unmet clinical need. Here, the validated methodology is reported for a novel hybrid tissue‐engineered vascular graft that aims match natural structure small‐size arteries. blood vessel mimic (BVM) comprises internal conduit co‐electrospun gelatin and polycaprolactone (PCL) nanofibers (corresponding tunica intima artery), reinforced by additional layer PCL aligned fibers (the elastic membrane). Endothelial cells...
Thyroid hormone (tri-iodo-thyronine, T3) exerts transcriptional effects on target genes in responsive cells. These are determined by DNA/protein interactions governed the type of T3 receptors (TRs) cell. As TRs show tissue and developmental variations, regulation is best addressed an integrated vivo model. We examined TR subtype thyrotropin-releasing (TRH) transcription pituitary/thyroid axis end point: thyroid secretion. Polyethylenimine served to transfect a TRH-luciferase construct...
Off-pump coronary artery bypass surgery reduces the myocardial injury associated with on pump cardiopulmonary (CPB) and ischemic-cardioplegic arrest (CA). We sought to find a mechanistic explanation for this by comparing transcriptomic changes in myocardium of patients undergoing on- off-pump surgery. Transcriptomic analyses were performed left ventricular biopsies obtained from prior (pre-op) after completion all anastomoses (post-op). Microarray results validated real-time polymerase chain...
Background/Aim: Endothelial cell migration is required for physiological angiogenesis, but also contributes to various pathological conditions, including tumour vascularization. The mRNA expression of PP1cβ, the beta isoform catalytic PP1 subunit, was shown be upregulated in chronic hypoxia. Since hypoxia a major regulator potential role PP1cβ angiogenesis investigated. Methods: We examined protein level pediatric heart following and found upregulation cyanotic compared with acyanotic...