A5102895544- Congenital Heart Disease Studies
- Sinusitis and nasal conditions
- Nasal Surgery and Airway Studies
- Helminth infection and control
- Radiomics and Machine Learning in Medical Imaging
- Coronary Artery Anomalies
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Anesthesia and Neurotoxicity Research
- Neuropeptides and Animal Physiology
- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Pharmacological Receptor Mechanisms and Effects
- interferon and immune responses
- Shoulder and Clavicle Injuries
- Ion Channels and Receptors
- Cardiac Arrest and Resuscitation
- Bone Tumor Diagnosis and Treatments
- Clostridium difficile and Clostridium perfringens research
- Infectious Diseases and Tuberculosis
- Oral and Maxillofacial Pathology
- Cardiac Ischemia and Reperfusion
- Respiratory Support and Mechanisms
- MRI in cancer diagnosis
- Extracellular vesicles in disease
Fudan University
2022
Huashan Hospital
2022
Second Military Medical University
2016-2020
Shanghai Changzheng Hospital
2015-2020
Shandong University
2019
Shanghai Jiao Tong University
2015-2016
Shanghai Children's Medical Center
2016
Memorial Sloan Kettering Cancer Center
2015
Shanghai Ninth People's Hospital
2015
Bethune Second Hospital
2014
Metastasis leads to poor prognosis in colorectal cancer patients, and there is a growing need for new therapeutic targets. TMEM16A (ANO1, DOG1 or TAOS2) has recently been identified as calcium-activated chloride channel (CaCC) reported be overexpressed several malignancies; however, its expression function (CRC) remains unclear. In this study, we found of mRNA protein high-metastatic-potential SW620, HCT116 LS174T cells, but not primary HCT8 SW480 using RT-PCR, western blotting...
The present study addressed the potential involvement of microRNAs in acute respiratory distress syndrome (ARDS)-related inflammation and elucidates underlying molecular mechanism.ARDS rat model was established by lipopolysaccharide, with compromised gas exchange capacity lung edema. inflammatory cells from bronchoalveolar lavage fluid (BALF) were profiled automatic blood cell analyzer. relative fluorescence intensity BALF-derived macrophages analyzed flow cytometry. microRNA expression...
Objectives The present study was undertaken to investigate the effects and related mechanisms of hypothermia on oxidative stress apoptosis caused by cardiac arrest (CA)-induced brain damage in rats.Methods CA/CPR model initiated asphyxia. Body temperature normothermia groups maintained at 37°C ± 0.2°C 34°C 0.2°C, respectively, surface cooling with an ice pack. First, neurological deficit scores (NDSs) were assessed, then hippocampus samples collected 24 72 h after return spontaneous...
BACKGROUND:The study aims to investigate the performance of a metagenomic next-generation sequencing (NGS)-based diagnostic technique for identifi cation potential bacterial and viral infections eff ects concomitant infection on survival rate intensive care unit (ICU) sepsis patients.METHODS: A total 74 ICU patients with who were admitted our institution from February 1, 2018 June 30, 2019 enrolled.Separate blood samples collected cultures NGS when patients' body temperature was higher than...
<b>Objective</b> To discuss the anatomical morphologies of coronary arteries and frequencies unusual in complete transposition great double outlet right ventricle (DORV) associated with a subpulmonic ventricular septal defect (VSD). <b>Methods</b> Between March 1999 August 2012, 1,078 patients or DORV subpulmonary VSD underwent arterial switch operations (ASOs) were visually evaluated to classify their artery morphology during open heart surgery. <b>Results</b> The could be classified into...
The programmed cell death 4 (PDCD4) has recently been recognized as a new and attractive target of acute respiratory distress syndrome. Here, we attempted to discover potent PDCD4 mediator ligands from biogenic compounds using synthetic strategy statistical virtual screening experimental affinity assay. In the procedure, Gaussian process‐based quantitative structure‐activity relationship regression predictor was developed validated statistically based on curated panel structure‐based...
Strongyloidiasis is usually a chronic infection but it can develop into fatal disease in immunosuppressed patients.A 68-year-old male with rheumatoid arthritis was treated variety of immunosuppressants for the past 3 years. Recently, patient presented partial small-bowel obstruction, petechia, coughing and peripheral neuropathy. The diagnosis difficult to clarify other hospitals. Our hospital found Strongyloides stercoralis larvae active movement routine stool sputum smears. disseminated...
Prädiktion der Aggressivität von Prostatakarzinomen mittels apparent diffusion coefficient (ADC)- Werten des diffusions-gewichteten MRTs alleine und in Kombination mit Transferkonstante Ktrans kontrastmittelgestützten MRTs.
Objective: To investigate the signaling pathway of kappa opioid receptor (κ-OR) on postresuscitation myocardial protection. Method: A total 120 male SD rats were randomized into control group (n=40), κ-OR agonist (n=40) and inhibitor (n=40). Asphyxia-induced cardiac arrest was performed by turning-off ventilator clamping endotracheal tube. Cardiac started when systolic blood pressure dropped below 25mmHg. CPR with chest compression mechanical ventilation 6mins after arrest. Normal saline...