A5100660451- Ultrasound in Clinical Applications
- Immune Response and Inflammation
- Non-Invasive Vital Sign Monitoring
- Sepsis Diagnosis and Treatment
- COVID-19 diagnosis using AI
- ECG Monitoring and Analysis
- Parasites and Host Interactions
- Phonocardiography and Auscultation Techniques
- Immune Cell Function and Interaction
- Hematopoietic Stem Cell Transplantation
- Radiology practices and education
- Neuroinflammation and Neurodegeneration Mechanisms
- COVID-19 Clinical Research Studies
- Acute Myeloid Leukemia Research
- Long-Term Effects of COVID-19
- Nosocomial Infections in ICU
- Plant-based Medicinal Research
- Pharmacological Effects of Natural Compounds
- Hemodynamic Monitoring and Therapy
- Digestive system and related health
- Voice and Speech Disorders
- Medicinal Plants and Bioactive Compounds
- Technology and Security Systems
- vaccines and immunoinformatics approaches
- Enhanced Recovery After Surgery
Shanghai Changzheng Hospital
2012-2024
Second Military Medical University
2003-2023
East China Normal University
2022
Sichuan University
2021
State Key Laboratory of Biotherapy
2021
Dalian Medical University
2014
Chongqing Medical University
2014
Second Affiliated Hospital of Chongqing Medical University
2014
Sun Yat-sen University
2011-2012
Ministry of Education of the People's Republic of China
2012
As being radiation-free, portable, and capable of repetitive use, ultrasonography is playing an important role in diagnosing evaluating the COVID-19 Pneumonia (PN) this epidemic. By virtue lung ultrasound scores (LUSS), (LUS) was used to estimate excessive fluid that clinical manifestation PN, with high sensitivity specificity. However, as a qualitative method, LUSS suffered from large interobserver variations requirement for experienced clinicians. Considering limitation, we developed...
Auxiliary diagnosis and monitoring of lung diseases based on ultrasound (LUS) images is important clinical research. A-line one the most common indicators LUS that can offer support for assessment diseases. A traditional detection method mainly relies experienced clinicians, which inefficient cannot meet needs these areas with backward medical level. Therefore, how to realize automatic in image important.In order solve disadvantages methods, accurate detection, provide theoretical...
Sepsis is a common complication of infections, burns, traumas, surgeries, poisonings, and post-cardiopulmonary resuscitation. The present study aimed to investigate prognostic value CD4(+)CD25(+) regulatory T cells (Treg) in peripheral blood patients with sepsis.Periphery from 28 diagnosed sepsis was collected on day 1 7 after hospitalization the ICU Shanghai Changzheng Hospital between December 2013 April 2014. used for analyses Treg ratio using flow cytometry routine test, C-reactive...
Abstract Pseudomonas aeruginosa infection continues to be a major threat global public health, and new safe efficacious vaccines are needed for prevention of infections caused by P. . X-ray irradiation has been used prepare whole-cell inactivated against infection. However, the immunological mechanisms X-ray-inactivated still unclear require further investigation. Our previous study found that an vaccine could provide protection boosting T cells. The aim present was explore vaccine. Herein,...
The video-based non-contact respiration detection technology can be used in many application scenarios to unobtrusively and ubiquitously monitor the physical state of living beings, various researchers are currently working on this technology. optical flow method tandem with crossover point is rather effective for rate extraction. However, each has one disadvantage: 1) redundant feature points traditional increase computational effort reduce estimation accuracy; 2) suffers from unrelated...
BACKGROUND:The study aims to investigate the performance of a metagenomic next-generation sequencing (NGS)-based diagnostic technique for identifi cation potential bacterial and viral infections eff ects concomitant infection on survival rate intensive care unit (ICU) sepsis patients.METHODS: A total 74 ICU patients with who were admitted our institution from February 1, 2018 June 30, 2019 enrolled.Separate blood samples collected cultures NGS when patients' body temperature was higher than...
ABSTRACT Background: Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome, are complicated pulmonary inflammatory conditions for which standard therapeutics still not well established. Although increasing research has indicated the anti-inflammatory, anticancer, antioxidant effects of luteolin, especially in diseases, molecular mechanisms underlying luteolin treatment remain largely unclear. Methods: The potential targets ALI were explored using a network...
Spinal cord injury (SCI) is the leading cause of paralysis, disability and even death in severe cases, neural stem cells (NSCs) transplant has been employed for repairing SCI. Ferulic acid (FA) able to promote neurogenesis various cell therapies. We aimed investigate effect FA on NSC therapy, underlying mechanism, improving functional recovery SCI rat model. A model was established, which then received NSCs with or without pre-treatment. Functional rats evaluated, terms spinal water content,...
Accurate assessment of pleural line is crucial for the application lung ultrasound (LUS) in monitoring diseases, thereby aim this study to develop a quantitative and qualitative analysis method line.
ABSTRACT Infections caused by multidrug-resistant pathogens are frequent and life threatening in critically ill patients. To investigate whether severe sepsis affects gut colonization resistant genetic exchange between opportunistic pathogens, we tested the intestinal-colonization ability of an extended-spectrum beta-lactamase-producing Klebsiella pneumoniae strain carrying SHV-18 resistance gene transfer to endogenous Escherichia coli under ceftriaxone treatment rats with burn injury only...
As two important features of COVID-19 pneumonia ultrasound, the B-line and white lung are easily confused in clinics. To classify features, a radiomics analysis technology was developed on set ultrasound images collected from patients with study. A total 540 filtered were divided into training test ratio 7:3. machine learning model proposed to perform automated classification lung, which included image segmentation, feature extraction, screening, classification. The radiomic applied extract...
We used RNA-sequencing (RNA-Seq) technology and an old hematopoietic stem progenitor cells (HSPCs) model in vitro to analyze differential expressions of mismatch repair (MMR)-related genes aged HSPCs, so as explore the mechanism DNA MMR injury (HSC) aging. In this study, by combining RNA-seq data National Center for Biotechnology Information database, we focus on six widely reported MSH2, MSH3, MSH6, MLH1, PMS1, PMS2, five with closer ties HSC aging Pcna, Exo1, Rpa1, Rpa2, Rpa3 according...
Lung ultrasound (LUS) is a valuable tool for bedside real-time monitoring of critically ill patients with respiratory diseases. Previous studies primarily focused on LUS frame level (FL), while this paper proposed video-level (VL) scoring model. Firstly, frames were scored by experienced clinicians and employed the LUS-FL This model was designed based dual attention vision transformer (DaViT), which uses hybrid self-attention mechanisms to extract local global features frames. Secondly, each...
Background: This study sought to examine fluid resuscitation in septic shock patients by monitoring their sublabial point of care microcirculation score (POEM) scores (a 3.5 cut-off value was used as the end recovery). It also explore effectiveness and safety using POEM shock. Methods: Patients were randomly allocated experimental group or control group. In group, a >3 resuscitation. doctor just monitor, don't know data. Patients' heart rates, mean arterial pressure (MAP), Acute Physiology...