A5024370855- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Vascular Procedures and Complications
- Abdominal vascular conditions and treatments
- Organ Transplantation Techniques and Outcomes
- Aortic aneurysm repair treatments
- IgG4-Related and Inflammatory Diseases
- Viral-associated cancers and disorders
- Congenital Anomalies and Fetal Surgery
- Hepatitis B Virus Studies
- Vascular Malformations and Hemangiomas
- Ultrasound Imaging and Elastography
- Uterine Myomas and Treatments
- Vascular Anomalies and Treatments
Chang Gung Memorial Hospital
2010-2023
Chang Gung University
2011-2022
Linkou Chang Gung Memorial Hospital
2005-2022
Creighton University
2015
Kaohsiung Chang Gung Memorial Hospital
2006
Taipei Veterans General Hospital
2006
Laboratory Imaging (Czechia)
2005
American Society of Echocardiography
2005
Memorial Hospital of South Bend
2003
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality in Taiwan. The Taiwan Liver Cancer Association and the Gastroenterological Society had established management consensus guideline 2016. current recommendations focus on updating critical issues regarding HCC, including surveillance, diagnosis, systemic treatment. For updated suggests role dynamic computed tomography or magnetic resonance imaging contrast-enhanced ultrasound (CEUS) selected patients. this update...
We studied the efficacy of magnetic resonance cholangiopancreatography (MRCP) in evaluation malignant perihilar biliary obstructions, with reference to endoscopic retrograde (ERCP).A total 40 patients who underwent both MRCP (Magnetom Vision; Siemens, Erlangen, Germany; projection technique and multislice plus maximum intensity projection) ERCP examinations, were studied. The study group included hilar cholangiocarcinoma (Klatskin tumor) 26 patients, icteric hepatocellular carcinoma four...
In Brief Objective: To propose a cholangiographic classification for intraductal growth type intrahepatic cholangiocarcinoma (IG-ICC) and its precursor, collectively termed papillary mucinous neoplasm of the bile ducts (IPMN-B). Summary Background Data: For extensive clinicopathologic variations IPMN-B, detailed characterization cholangiography IPMN-B is beneficial determining optimal therapeutic strategy. Methods: A total 124 patients with cholangiography-available pathologically proven...
Abstract A cohort of patients with intraductal growth-type intrahepatic cholangiocarcinoma (IG-ICC) and its precursor lesions, collectively termed papillary neoplasm the liver (IPNL), was characterized respect to demographics, clinical manifestations, perioperative management, long-term survival, molecular features associated carcinogenesis. total 122 IPNL types 1 through 4, 108 non–IG-ICC 210 hepatolithiasis alone were studied. Expression CDX2, TFF1, MUC1, MUC2, MUC5AC, EGFR, p53 determined...
Abstract Background. Opinions regarding the impact of human epidermal growth factor receptor (HER)-2 overexpression or HER-2 amplification on prognosis gastric cancer patients are mixed. The present study attempted to clarify this issue by investigating a large cohort surgical patients. Methods. We investigated 1,036 undergoing curative-intent resection. Their specimens were evaluated for expression immunohistochemistry (IHC), and those with levels 2+ additionally subjected fluorescence in...
Abstract Purpose Imatinib mesylate (IM) demonstrates substantial efficacy in most patients with metastatic gastrointestinal stromal tumors (GISTs). However, progression of GIST eventually develops and emerges as a challenge. To assess the role surgery multidisciplinary management GISTs, we studied surgical outcomes receiving IM. Materials Methods Between 2001 May 2009, 161 received Among them, 35 undergoing 38 surgeries were investigated. Patients categorized based on extent disease before...
Alterations of adipocytokine levels and clinical parameters in non-alcoholic fatty liver disease (NAFLD) are crucial for the prognosis complications diseases. However, key adipocytokines independently associated with NAFLD have not been identified, we aimed to investigate them.This study was conducted on a consecutive series 210 Taiwanese patients 420 sex- age-matched controls. Fatty diagnosed by magnetic resonance spectroscopy. The enrolled subjects' body mass indexes, homeostasis model...
This study was designed to assess the clinical usefulness of imaging for predicting prognosis patients with combined hepatocellular cholangiocarcinoma (cHCC-CC). Between 1999 and 2004, 30 histopathologically proven cHCC-CC underwent computed tomography (CT) or magnetic resonance (MRI). The data survival were analysed. Univariate log-rank analysis findings revealed that tumour necrosis, bile duct invasion, major vascular branch multiplicity, bilobar distribution, regional lymph node...
The homodyned-K (HK) distribution is an important statistical model for describing ultrasound backscatter envelope statistics. HK parametric imaging has shown potential characterizing hepatic steatosis. However, the feasibility of in assessing human steatosis vivo remains unclear.In this paper, μ was proposed vivo. Two recent estimators model, RSK (the level-curve method that uses signal-to-noise ratio (SNR), skewness, and kurtosis based on fractional moments envelope) XU estimation first...
Our preliminary report of imatinib mesylate (IM) in gastrointestinal stromal tumor (GIST) patients detailed a high response rate; however, the long-term result is still unknown. We conducted an analysis Taiwan advanced inoperable/metastatic GIST treated on IM regarding survival, pattern failure, potential prognostic factors, and mutational status.From 2001 to 2010, with pathologically proven receiving were enrolled onto this study. Data KIT status, measurable size, other factors...
To investigate the diagnostic accuracy of 68Ga-DOTATOC and 18F-FDG PET/CT to identify primary foci in Taiwanese patients with clinically suspected neuroendocrine tumors (NET) NET unknown site. Patients site were eligible. All participants underwent a conventional workup (including CT, MR, endoscopic ultrasound), 68Ga-DOTATOC, PET/CT. The results pathology findings on clinical follow-up served as gold standard. Among 36 included study, we able tumor 17 (47.2%). overall sensitivity values...
Annular pancreas is most often found in neonates and infants younger than 1 year of age. adults rare clinically identifiable when symptomatic. Upper gastrointestinal radiography surgical confirmation were the common methods for diagnosing annular 1950s to 1980s. However, revolution image modalities has enabled preoperative diagnosis last 20 years. Many have also been developed, one used depends on presentation extent annulus. We report two cases symptomatic adult at Chang Gung Memorial...
Objective: To investigate the clinical outcomes and failure patterns of patients with unresectable cholangiocarcinoma (CC) who had been treated proton beam therapy (PBT). Methods: The authors retrospectively examined 30 CC undergone PBT between November 2015 December 2017. Survival curves were plotted Kaplan-Meier method. Independent predictors survival identified by multivariate Cox proportional hazard regression analyses. Complications assessed using Common Terminology Criteria for Adverse...
In patients with advanced hepatocellular carcinoma (HCC), combination chemotherapy using 5- fluorouracil, cisplatin, and mitoxantrone (FMP) could achieve a response rate > 20%, but the beneficial effect was compromised by formidable adverse events. Chemotherapy given in split-dose manner associated reduced toxicities. this retrospective study, we compared efficacies side effects between regular FMP protocol approved our medical center. From 2005 to 2008, clinical data of 84 far HCC, who had...