A5018771571- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Vascular Anomalies and Treatments
- Kruppel-like factors research
- Nutrition and Health in Aging
- Public Administration and Political Analysis
- Frailty in Older Adults
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Polyomavirus and related diseases
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Potassium and Related Disorders
- Acute Myocardial Infarction Research
- Pericarditis and Cardiac Tamponade
- Viral-associated cancers and disorders
- Eosinophilic Disorders and Syndromes
- CNS Lymphoma Diagnosis and Treatment
- Acute Kidney Injury Research
Saitama Medical University
2012-2021
National Cerebral and Cardiovascular Center
2020-2021
Massachusetts General Hospital
2021
Hospital Universitario La Paz
2021
Amyloidosis Foundation
2021
Research Network (United States)
2021
Montefiore Medical Center
2021
National Heart Foundation of Australia
2021
Saitama International Medical Center
2018-2020
Saitama University
2020
Abstract Aims Predictive models for heart failure patients are widely used in the clinical practice to stratify patients' mortality and enable clinicians tailor intensify their approach. However, such have not been validated internationally. In addition, biomarkers now frequently measured obtain prognostic information, implications of this known. study, we aimed validate model performance Meta‐analysis Global Group Chronic Heart Failure (MAGGIC) score a Japanese acute registry further...
The natural course of heart failure (HF) is typically associated with repeated hospitalizations, and subsequently, patient prognosis deteriorates. However, the precise relationship between admissions for HF long-term remains unknown.
Abstract Aims The blood urea nitrogen (BUN)/creatinine ratio is a strong prognostic indicator in patients with acute decompensated heart failure (ADHF). However, the clinical impact of high BUN/creatinine at discharge respect to renal dysfunction, neurohormonal hyperactivity, and different responsiveness decongestion therapy remains unclear. Herein, we examined (i) predictive value (ii) its haemoconcentration‐dependent effects, ADHF. Methods results West Tokyo Heart Failure registry was...
Background: The concept of Clinical Scenario (CS) classification has been widely utilized to aid in choosing appropriate management strategies for acute decompensated heart failure (ADHF).
Sarcopenia is characterized by progressive loss of skeletal muscle and has frequently been associated with poor clinical outcomes in patients advanced heart failure (HF). The urinary creatinine excretion rate (CER) index an easily measured marker mass, but its predictive capacity for mortality cerebrovascular events not investigated a continuous-flow implantable left ventricular assist device (CF-iLVAD).
Appropriate indications and protocols for induction therapy using basiliximab have not been fully established in heart transplant (HTx) recipients. This study elucidated the influence of along with delayed tacrolimus (Tac) initiation on outcomes high-risk HTx
Abstract Aims The impact of worsening renal function (WRF) on the prognosis patients with acute heart failure (AHF) remains controversial. We aimed to identify phenotypically distinct subgroups among individuals both AHF and WRF using cluster analysis. Methods results Overall, data 483 enrolled in West Tokyo Heart Failure Registry were analysed. Using analysis, we identified three (phenogroups 1, 2, 3). assessed each phenogroup by comparing incidence composite endpoints, including all‐cause...
Abstract Aortic insufficiency (AI) is an important adverse event in patients with continuous-flow (CF) left ventricular assist device (LVAD) support. AI often progressive, resulting elevated 2-year morbidity and mortality. The effectiveness of echocardiographic ramp studies has been unclear. Here, we describe a patient CF-LVAD implant who underwent aortic valve replacement (AVR), following assessment using hemodynamic test simultaneous echocardiography right heart catheterization (RHC). was...
Essential thrombocythemia (ET) is a Philadelphia chromosome-negative myeloproliferative disorder that characterized by the overproduction of platelets and marked increase in numbers mature megakaryocytes present bone marrow. Thrombohemorrhagic disorders are major morbidities ET, especially those with mutations gene encoding Janus kinase 2 (JAK2). In this study, we report case an 18-year-old patient ET carrying JAK2 mutation who developed acute ST-elevation myocardial infarction (STEMI) 5...
Implantable left ventricular assist devices (LVAD) have improved quality of life and survival in patients with advanced heart failure. However, LVAD-specific infections predicting which will develop remain challenging. This study investigated whether changes body mass index (BMI) during hospitalization following LVAD implantation are associated within 1 year implantation.
Introduction: Current prognostic models to predict survival in heart transplant (HTx) recipients, which are ‘Index for Mortality Prediction After Cardiac Transplantation (IMPACT) model’ using the recipient-factor and ‘International Heart Survival Algorithm (IHTSA) both recipient- donor-factors, have been verified good adaptation on global registry data HTx recipients. In Japan, extremely serious donor shortages will necessitate a long waiting period, more marginal hearts. But several risk...
Thrombohemorrhagic disorders are the main cause of morbidities and mortalities essential thrombocythemia (ET), which typically observed at age 50–60 years rarely encountered in adolescence or childhood. Recently, anagrelide, a quinazinolone derivative, has been used as therapeutic agent for ET. Although it is to reduce platelet count, its cardiotoxicity reported. Here, we present an 18-year-old boy with ET who was treated anagrelide developed acute myocardial infarction. This presumed be...
Acquired coarctation of the aorta (CoA) following total aortic arch replacement (TAR) is a rare complication inducing left ventricular (LV) dysfunction probably due to increased LV afterload and secondary hypertension caused by upper body decreased renal blood flow. We describe case 35-year-old male who developed atypical CoA with severe ejection fraction 10%, but without after TAR using conventional elephant trunk (ET) technique for acute dissection. Computed tomography revealed...
AimsSince ACE cleaves carboxyl-terminal dipeptides of various oligopeptides such as Ang I, kinins, (1-7) and matrix metalloproteases, inhibitors have exerted pleiotropic effects independent renin-angiotensin system inhibition. Therefore, we examined the ACEI in left ventricular (LV) diastolic dysfunction caused by chronically II stimulation. The goal this study was to discover an effective treatment using ACEIs.Methods resultsWith Sprague-Dawley rats, Echocardiography performed on two...