- Migraine and Headache Studies
- Bacterial biofilms and quorum sensing
- Ophthalmology and Eye Disorders
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Sympathectomy and Hyperhidrosis Treatments
- Trigeminal Neuralgia and Treatments
- Microbial Inactivation Methods
- Mosquito-borne diseases and control
- Neurosurgical Procedures and Complications
- Neurological Complications and Syndromes
- Intracerebral and Subarachnoid Hemorrhage Research
- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Viral Infections and Immunology Research
- Advanced Neuroimaging Techniques and Applications
- Neuroscience of respiration and sleep
- Alzheimer's disease research and treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Historical and Scientific Studies
- Cerebral Venous Sinus Thrombosis
- Pharmacological Effects and Toxicity Studies
- Infectious Encephalopathies and Encephalitis
- Cerebrovascular and Carotid Artery Diseases
- Oral microbiology and periodontitis research
Gyeongsang National University Hospital
2014-2025
Gyeongsang National University
2011-2023
National University College
2020
Mayo Clinic Hospital
2020
New Generation University College
2020
Chonnam National University Hospital
2018
Chungnam National University Hospital
2018
Pusan National University
2014
Hanyang University
2008
CHA University
2004
Stem cell-based therapy is a promising approach to repair brain damage after stroke. This study was conducted investigate changes in neuroimaging measures using stem patients with ischemic stroke.In this prospective, open-label, randomized controlled trial blinded outcome evaluation, severe middle cerebral artery territory infarct were assigned the autologous mesenchymal cell (MSC) treatment or control group. Of 54 who completed intervention, 31 for MSC and 13 groups included analysis. Motor...
Background Vestibular migraine (VM), the common term for recurrent vestibular symptoms with features, has been recognized in appendix criteria of third beta edition International Classification Headache Disorders (ICHD-3β). We applied VM a prospective, multicenter headache registry study. Methods Nine neurologists enrolled consecutive patients visiting outpatient clinics headache. The presenting disorder and additional diagnoses were classified according to ICHD-3β. rates diagnosed probable...
Background and purpose Acute ischemic stroke (AIS) caused by basilar artery occlusion (BAO) is a very severe neurological disease with high mortality rate poor clinical outcomes. In this study, we compared our experience of mechanical thrombectomy using the Solitaire stent (Solitaire thrombectomy) manual aspiration Penumbra reperfusion catheter (Penumbra suction in patients AIS BAO. Materials methods Between March 2011 December 2011, 13 received thrombectomy. January 2012, Korean Food Drug...
Importance Nelonemdaz selectively antagonizes the 2B subunit of N -methyl- d -aspartate glutamate receptor and scavenges free radical species. Objective To evaluate whether nelonemdaz enhances clinical outcomes patients with acute ischemic stroke undergoing emergent reperfusion therapy. Design, Setting, Participants This multicenter double-blind placebo-controlled randomized phase 3 trial (December 25, 2021, to June 30, 2023, in South Korea) recruited who met following criteria: National...
Comprehensive Application of the International Classification Headache Disorders Third Edition, Beta VersionThe purpose this study was to test feasibility and usefulness Disorders, third edition, beta version (ICHD-3β), compare differences with second edition (ICHD-2).Consecutive first-visit patients were recruited from 11 headache clinics in Korea.Headache classification performed accordance ICHD-3β.The characteristics headaches analyzed assessed by proportion unclassified disorders...
Background and PurposezzNew-onset headache in elderly patients is generally suggestive of a high probability secondary headache, the subtypes primary diagnoses are still unclear elderly.This study investigated characteristics with an older age at onset (≥65 years) compared between younger groups.MethodszzWe prospectively collected demographic clinical data 1,627 who first visited 11 tertiary hospitals Korea due to August 2014 February 2015.Headache subtype was categorized according...
Background Only limited data are available regarding the treatment status and response to cluster headache in an Asian population. Therefore, this study aimed provide a real-world pattern of rate each Methods Patients with were recruited between September 2016 January 2019 from 16 hospitals Korea. At baseline visit, we surveyed patients about their previous experience treatment, acute and/or preventive treatments prescribed at physician’s discretion. Treatment was prospectively evaluated...
Chronic daily headache (CDH) is defined as a disorder in which headaches occur on or near-daily basis (at least 15 days/month) for more than 3 months. migraine (CM) and medication overuse (MOH) are very disabling that remain underdiagnosed. The aim of this study was to establish the frequency CDH its various subtypes, examine associations with MOH among first-visit patients presenting at neurology outpatient clinics Korea.Eleven neurologists enrolled complaints into further assessment....
Patients with cluster headache (CH) exhibit impaired health-related quality of life (HRQoL). However, there have been few studies related to the HRQoL patients CH from Asian backgrounds. This study aimed determine impact on and identify factors affecting in during periods.
Members of the large family Asb proteins are ubiquitously expressed in mammalian tissues; however, roles individual and their function developmental testes have not been reported. In this report, we isolated a murine Asb4 from mouse testis. Northern blot analysis revealed that mAsb-4 was only produced stage-specific manner during spermatogenesis. It beginning fourth week after birth extending into adulthood. Pachytene spermatocytes had highest level expression. Interestingly, human homologue...
A "Probable headache disorder" is diagnosed when a patient's fulfills all but one criterion of disorder in the 3rd beta edition International Classification Headache Disorder (ICHD-3β). We investigated diagnostic changes probable disorders first-visit patients after at least 3 months follow-up. This was longitudinal study using prospective registry from nine clinics referral hospitals. The change baseline assessed initial visit ICHD-3β. Of 216 with baseline, diagnosis remained unchanged for...
Background and Purpose:We conducted this study to define the relationship between hyperventilationinduced EEG changes (HV-EEG changes) PCO2 Methods: In consecutive recordings of 190 patients, we gathered data on during hyperventilation procedure.The included baseline (B-PCO2), after 5 min (5 min-PCO2), mean value (M-PCO2), difference B-PCO2 min-PCO2 (ΔPCO2).We divided enrolled patients into two groups by response (response group no-response group), presence epilepsy (epileptic non-epileptic...
Korea is one of the fastest aging country in world. As old population increases, incidence stroke would rapidly increase. We estimated future neurologist supply Korea, and assessed whether present appropriate to cope with increase stroke. reviewed resource database neurologists affiliated Korean Neurological Association. Age, sex, location workplace, work positions were identified. The was calculated from age group specific data projected number. Age adapted 2006 report Construction National...
Background and Purpose Deciding whether or not to perform neuroimaging in primary headache is a dilemma for physicians.The aim of this study was identify clinical predictors incidental abnormalities new patients with disorders.Methods This cross-sectional based on prospective multicenter registry, it classified 1,627 consecutive first-visit according the third edition (beta version) International Classification Headache Disorders (ICHD-3β).Primary who underwent were finally enrolled...
Although many schizencephaly patients suffer from epilepsy, the relationship between schizencephalic lesions and epileptic foci remains unclear. Previous studies have shown that may be associated with, rather than contain, epileptogenic zones. Thus, purpose of this study was to investigate current source distribution (CSD) epileptiform discharges in correlate activity with existing structural lesions. A consecutive series 30 who were diagnosed using brain magnetic resonance imaging (MRI)...
Abstract Background Close associations between insomnia with other clinical factors have been identified in migraine, but there few studies investigating and patients persistent post-traumatic headache (PPTH). The study objective was to contrast the severity of symptoms PPTH, healthy controls, identify associated PPTH vs. migraine. Methods In this cross-sectional cohort study, 57 individuals attributed mild traumatic brain injury, 39 controls were included. Participants completed a detailed...
Received June 2, 2014 Revised September 19, Accepted Address for correspondence: Oh-Young Kwon, MD Department of Neurology, Gyeongsang National University School Medicine, 816-15 Jinju-daero, Jinju 660-751, Korea Tel : +82-55-750-8077 Fax +82-55-755-1709 E-mail mnkwon21@daum.net 발작 이후 뇌에 발생하는 발작유발뇌부종(seizure-induced cerebral edema)은 뇌피질과 피질하부에 주로 발생하며, 한쪽 뇌반 구에 국한되어 나타나는 경우가 많다. 발작유발뇌부종은 뇌자 기공명영상(brain magnetic resonance imaging)의 T1강조영상 (T1-weighted image)에서 저신호강도를 보이고, 액체감쇠역전 회복영상(fluid...