A5091219425- Vector-borne infectious diseases
- Insect and Pesticide Research
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Research on Leishmaniasis Studies
- Insect symbiosis and bacterial influences
- Insect Pest Control Strategies
- Mosquito-borne diseases and control
- Physiological and biochemical adaptations
- Enzyme Production and Characterization
- Invertebrate Immune Response Mechanisms
- Trypanosoma species research and implications
- Carcinogens and Genotoxicity Assessment
- Environmental Toxicology and Ecotoxicology
- Antimicrobial Peptides and Activities
- Parasite Biology and Host Interactions
- Microbial Inactivation Methods
- Insect Resistance and Genetics
- Listeria monocytogenes in Food Safety
- Synthesis and Characterization of Heterocyclic Compounds
- Parasites and Host Interactions
- Probiotics and Fermented Foods
- Toxin Mechanisms and Immunotoxins
Universidade Federal do Rio Grande do Sul
2015-2022
Universidade Federal de Pelotas
2015
The ticks Rhipicephalus appendiculatus and sanguineus are the main vectors of Theileria parva Babesia spp. in cattle dogs, respectively. Due to their impact veterinary care industry, improved methods against R. parasitism under development, including vaccines. We have previously demonstrated induction a cross-protective humoral response microplus following vaccination with recombinant glutathione S-transferase from Haemaphysalis longicornis tick (rGST-Hl), suggesting that this protein could...
Cocktail vaccines are proposed as an attractive way to increase protection efficacy against specific tick species. Furthermore, such made with different antigens have the potential of cross-protecting a broad range However, there still limitations selection immunogen candidates. Acknowledging that glutathione S-transferases (GSTs) been exploited ticks and other parasites, this study aimed analyze GST-cocktail vaccine broad-spectrum vaccine. To constitute vaccine, five species economic...
Abstract To further obtain insights into the Rhipicephalus microplus transcriptome, we used RNA-seq to carry out a study of expression in (i) embryos; (ii) ovaries from partially and fully engorged females; (iii) salivary glands (iv) fat body (v) digestive cells partially, (vi) females. We obtained > 500 million Illumina reads which were assembled de novo, producing 190,000 contigs, identifying 18,857 coding sequences (CDS). Reads each library mapped back transcriptome giving view gene...
Cystatins are a group of cysteine protease inhibitors responsible for physiological proteolysis regulation and present in wide range organisms. Studies about this class parasites have contributed to clarify their roles important processes, like blood digestion modulation host immune response during feeding. Thus, cystatins subject research on the development new parasite control methods. Additionally, characterization proteins shared by different species represents valuable strategy find...
Reactive oxygen species (ROS) are natural byproducts of metabolism that have toxic effects well documented in mammals. In hematophagous arthropods, however, these processes not largely understood. Here, we describe Rhipicephalus microplus ticks and embryonic cell line (BME26) employ an adaptive metabolic compensation mechanism confers tolerance to hydrogen peroxide (H2O2) at concentrations too high for others organisms. Tick survival reproduction affected by H2O2 exposure, while BME26 cells...
Introduction: Ticks are hematophagous ectoparasites that cause significate economical losses. Acaricide application is the main method to tick control. However, it causes environmental contamination and selects resistant ticks. The immunological control represents a suitable replace or complement acaricide application. During its life cycle, female ticks ingest large amounts of blood, which contains toxic components able damage biomolecules. Understanding molecular mechanisms proteins...