A5108054603- RNA modifications and cancer
- Regulation of Appetite and Obesity
- Cancer-related molecular mechanisms research
- Malaria Research and Control
- Nanoparticle-Based Drug Delivery
- MicroRNA in disease regulation
- Anesthesia and Pain Management
- Immune Response and Inflammation
- Pituitary Gland Disorders and Treatments
- Biochemical Analysis and Sensing Techniques
- Tea Polyphenols and Effects
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Circular RNAs in diseases
- Infrared Thermography in Medicine
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Genomics and Diagnostics
- Cardiac Imaging and Diagnostics
- Glioma Diagnosis and Treatment
- Intraocular Surgery and Lenses
- Adipokines, Inflammation, and Metabolic Diseases
- Lung Cancer Treatments and Mutations
- Genomics, phytochemicals, and oxidative stress
- Gastrointestinal Tumor Research and Treatment
- Dietary Effects on Health
Shanxi Medical University
2025
First Hospital of Shanxi Medical University
2025
China Geological Survey
2024-2025
Guangxi Medical University
2019-2024
Ministry of Education of the People's Republic of China
2024
Ministry of Natural Resources
2024
First Affiliated Hospital of GuangXi Medical University
2023-2024
Beijing University of Chinese Medicine
2024
Jinzhou Medical University
2024
Tianjin Medical University Cancer Institute and Hospital
2014-2023
Background:The aim of this study was to evaluate the ability dual acridine orange/ethidium bromide (AO/EB) staining detect tumor cell apoptosis.According apoptosis-associated changes membranes during process apoptosis, a clear distinction is made between normal cells, early and late apoptotic necrotic cells. Material/Method:We cultured human osteosarcoma cells with 30, 60, 120 µg/ml kappa-selenocarrageenan.To assess rates proliferation were fluorescently stained or propidium iodide (PI)...
Syndecan-1 (Sdc-1) shedding induced by matrix metalloproteinase-7 (MMP-7) and additional proteases has an important role in cancer development. However, the impact of Sdc-1 on chemotherapeutic resistance not been reported. We examined colorectal enzyme-linked immunosorbent assay (ELISA), Dot blot, reverse transcription-PCR (RT-PCR), immunohistochemistry so on, its sensitivity collagen gel droplet embedded culture-drug test (CD-DST) MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium...
Evidence from observational studies for the effect of tea consumption on obesity is inconclusive. This study aimed to verify causal association between and through a two-sample Mendelian randomization (MR) analysis in general population-based datasets. The genetic instruments, single nucleotide polymorphisms (SNPs) associated with habits, were obtained genome-wide (GWAS): UK Biobank, Nurses' Health Study, Professionals Follow-up Women's Genome Study. instruments was analyzed using Biobank...
Abstract Chinese peony ( Paeonia lactiflora Pall.) is both medicinally and aesthetically beneficial. Powdery mildew a common fungal disease that seriously jeopardizes the value of numerous species, including peonies as crop. In order to provide basis for prevention treatment powdery mildew, we examined microbial diversity, malondialdehyde (MDA) concentrations antioxidant enzyme activities leaves infected with three levels determine any modifications leaf's systems community structure...
Abstract Objective This retrospective observational study aims to develop and validate artificial intelligence (AI) pathomics models based on pathological Hematoxylin–Eosin (HE) slides immunohistochemistry (Ki67) for predicting the staging of colorectal cancer. The goal is enable AI‐assisted accurate staging, supporting healthcare professionals in making efficient precise assessments. Methods included a total 267 cancer patients (training cohort: n = 213; testing 54). Logistic regression...
To investigate the influence of early dysphagia on quality life in patients with partial laryngectomy, and to application value Flexible Endoscopic Evaluation Swallowing (FEES). This study included 30 inpatients who underwent laryngectomy due laryngeal cancer. In postoperative period, a comprehensive assessment was conducted each patient, encompassing Videofluoroscopic Study (VFSS), (FEES), MD Anderson Dysphagia Inventory (MDADI). Each patient two evaluations at different time points...
Rhinobyon and inflammation associated with pollinosis may elevate the risk of obstructive sleep apnea hypopnea syndrome (OSAHS). However, exact nature this association remains unclear, particularly in large-scale populations. This study aimed to examine relationship between OSAHS using data from National Health Nutrition Examination Survey (NHANES). Data NHANES spanning 2005 2018 were analyzed. Three multivariate generalized linear models (GLMs) employed explore OSAHS: one unadjusted model,...
Land-use transition has diverse influences on habitat quality. At present, land-use patterns and quality in the ecologically fragile Yellow River Basin are undergoing significant change. However, relationship between driving factors of dynamics across whole basin remain unclear. In this study, we utilized a matrix an InVEST model to analyze land use, quality, two from 2005 2020. The were explored with spatial econometric model. results showed following: (1) areas farmland grassland accounted...
The electron beam melting (EBM) Ti-6Al-4V material technology has been developed over a short time period. It was introduced through research to develop implants for patients, but EBM printed locking compression plates have not used clinical implants. main purpose of this study is find whether the plate suit implants.First, we scanned an AO-locking (LCP) and LCP samples using EBM. Next, evaluated surface roughness optical microscopy as well plates' mechanical characteristics ASTM standard,...
This study aimed to evaluate whether (-)-epigallocatechin-3-gallate (EGCG) alleviates hepatic responses lipopolysaccharide (LPS)-induced inflammation and oxidation. Isolated bovine hepatocytes BALB/c mice were used for LPS challenge EGCG pretreatment experiments in vitro vivo. LPS-challenged (6 μg/mL) exhibited increased levels of NF-κB (p65 IκBα) MAPK (p38, ERK, JNK) phosphorylation as well binding activity p65 target pro-inflammatory gene promoters, these effects suppressed by with 50 μM...
Although long non-coding RNAs (lncRNAs) have been demonstrated to be dysregulated in gastric cancer (GC), the function of lncRNA HCG18 (HCG18) GC is elusive. Therefore, study was designed evaluate underlying mechanism GC. and microRNA 146a-5p (miR-146a-5p) levels were evaluated by RT-qPCR. The effects miR-146a-5p on cell examined using Transwell assay, colony formation, CCK-8 assays. Tumor necrosis factor receptor-associated 6 (TRAF6) p65 expression detected Western blot. target genes...
To investigate the effectiveness of intermittent pneumatic compression (IPC) devices combined with anticoagulants for prevention deep vein thrombosis (DVT) after total knee arthroplasty (TKA).In 120 patients were involved in this pilot study. Patients control group received 10 mg rivaroxaban per day surgery. In addition to prescription rivaroxaban, IPC used experimental group. The diagnosis DVT was made by duplex ultrasound on postoperative 9.The incidence rates overall, proximal, distal,...
This study aimed to explore the role and underlying molecular mechanisms of long non-coding RNA (lncRNA) LINC00342 in gastric cancer (GC).The expression GC tissues was evaluated by Quantitative reverse transcription polymerase chain reaction (qRT-PCR). Silencing conducted investigate effect vitro vivo. The were determined dual luciferase reporter assay, Western blotting analysis rescue experiments. Biological functions cell counting kit-8 (CCK-8) colony formation wound healing assay...
Background/Aims: Chronic alcohol abuse is an important risk factor for osteopenia. However, few studies have focused on the efficacy and mechanism of action icariin alcohol-induced The aim this study was to investigate underlying in treatment chronic high-dose osteopenia a rat model. Methods: Thirty-six adult male Sprague-Dawley rats were randomly divided into four groups: sham, alcohol, low-dose groups. Bone volume fraction (BV/TV), bone mineral density (BMD), biomechanical properties,...