A5091901982- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Reproductive System and Pregnancy
- PARP inhibition in cancer therapy
- Venous Thromboembolism Diagnosis and Management
- Gynecological conditions and treatments
- Estrogen and related hormone effects
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Bariatric Surgery and Outcomes
- Colorectal and Anal Carcinomas
- Impact of Technology on Adolescents
- Pregnancy-related medical research
- BRCA gene mutations in cancer
- Anesthesia and Pain Management
- Nausea and vomiting management
- Lymphoma Diagnosis and Treatment
- Patient-Provider Communication in Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Social Media in Health Education
- Mobile Health and mHealth Applications
- Pain Management and Opioid Use
Inha University Hospital
2020-2025
Kangdong Sacred Heart Hospital
2016-2021
Hallym University
2016-2021
Seoul National University Bundang Hospital
2014-2017
Yale University
2008
The eutopic endometrium in women with endometriosis demonstrates diminished endometrial receptivity and altered gene expression. It is unknown if the being defective gives rise to a predisposition toward infertility or, alternatively, causes receptivity. Here we created experimental mice examined expression of several markers endometrium. Methylation Hoxa10 was also evaluated as potential mechanism responsible for Expression each measured using quantitative real-time RT-PCR at 14 wk after...
The effect of hormone replacement therapy (HRT) on the malignant transformation postmenopausal endometriosis remains unclear. This study aimed to investigate impact HRT ovarian cancer occurrence in women with de novo or a history endometriosis. A total 10,304 that received (the group) and did not control were selected by 1:1 matching those met criteria. Incidences (0.3% group 0.5% cumulative incidence rates similar two groups. overall mean duration was 1.4 ± 2.2 years, but 2.9 years. After...
Background/Objectives: The survival outcomes according to postoperative adjuvant therapeutic strategy in women with high-risk early-stage endometrial cancer (EEC) have not been clearly compared. This study examined the impacts of various therapies on EEC. Methods: Korean Health Insurance Review and Assessment Service data related registration were used. 1341 who met eligibility criteria for EEC selected. overall (OS) after had received was analyzed. Results: mean age 58.2 ± 10.3 years, they...
Neoadjuvant chemotherapy followed by concurrent chemoradiation therapy (NACT + CCRT) and adjuvant following CCRT (CCRT ACT) have inconsistent effects on the survival of women with locally advanced cervical cancer (LACC) compared to CCRT. Moreover, NACT ACT not been clearly compared. This study using a network meta-analysis select optimal treatment in LACC. The PubMed, Medline, Embase databases were searched, six randomized controlled trials assessing progression-free (PFS) overall (OS) newly...
We updated the Korean Society of Gynecologic Oncology (KSGO) practice guideline for management ovarian cancer as version 5.1. The team KSGO published announced fifth (version 5.0) its clinical guidelines in December 2023. In 5.0, selection key questions and systematic reviews were based on data available up to 2022. Therefore, we 5.0 with newly accumulated added 5 new reflecting latest insights field between 2023 2024. For each question, recommendation was provided together corresponding...
Evidence has shown that multidisciplinary tumor board conferences (MTBCs) improve patient management for various cancer types. However, few retrospective studies have investigated MTBC efficacy patients with gynecologic cancers. Here, we prospectively aimed to evaluate how MTBCs influence in oncology. This prospective study included 85 consecutive cases were presented at oncology our tertiary university hospital between January 2015 and April 2016. The primary endpoint was treatment plan...
This study examined the impact of hormone replacement therapy (HRT) on occurrence various cancers in postmenopausal women with de novo or a history endometriosis. In datasets for ten (cervical, uterine, ovarian, breast, colon, gastric, liver, lung, pancreatic, and thyroid), who received HRT (the group) those did not control were selected by 1:1 matching met criteria. dataset each cancer, incidence cancer was very low (0.2% to 1.5% group 0.2% 1.3% group). The duration 1.3 ± 2.1 years. After...
We aimed to predict the risk of postoperative adjuvant therapy using preoperative variables in young patients with early stage cervical cancer. The predicted can guide whether ovarian transposition should be performed during surgery.
The aim of this study was to evaluate circulating tumor cell (CTC) detection in the differential diagnosis adnexal masses. A total 87 preoperative women with an indeterminate mass were prospectively enrolled. Preoperative diagnostic modalities including CTC detection, risk ovarian malignancy algorithm, index, and computed tomography or magnetic resonance imaging compared. Forty-three (49.4%) benign tumors, 13 (14.9%) borderline malignant masses, 31 (35.7%) cancers pathologically confirmed....
Outcomes of patients with ovarian high-grade serous carcinoma (HGSC) treated neoadjuvant chemotherapy (NAC) have been widely studied, but there is limited information on the outcomes non-HGSC. This study aimed to evaluate NAC in non-HGSC advanced-stage cancer. We conducted a retrospective cohort who underwent for advanced stage between 2002 and 2017 17 institutions. Demographics, surgical outcomes, survival rates were evaluated according histological subtypes. A total 154 included this...
This study aimed to determine the factors influencing patients' choice of physician at first visit through database analysis a tertiary hospital in South Korea. We collected data on treatments performed by physicians who had treated patients for least 3 consecutive years over 10 (from 2003 2012) from Seoul National University's affiliated hospital. Ultimately, we obtained 524,012 319,004 115 physicians. Variables including physicians' age and medical school were evaluated as number each year...
Objectives Fertility-sparing treatment (FST) might be considered an option for reproductive patients with low-risk endometrial cancer (EC). On the other hand, matching rates between preoperative assessment and postoperative pathology in EC are not high enough. We aimed to predict depending on myometrial invasion (MI) grade help extend current criteria FST. Methods/Materials This ancillary study (KGOG 2015S) of Korean Gynecologic Oncology Group 2015, a prospective, multicenter included no MI...
Objective This study aimed to investigate risk factors of progression endometrial cancer (EC) in women with non-atypical and atypical hyperplasia (EH). Methods The data 62,333 EH diagnostic codes from 2007 2018 were sourced the Korean Health Insurance Review Assessment Service databases. 11,525 2,219 who met selection criteria extracted for analysis. Results Risk EC decreased 40–49 year olds compared other ages (non-atypical EH: [≤39 vs. years] HR, 0.557; 95% CI, 0.439–0.708; P< 0.001;...
Abstract This study investigated incidence and risk factors for venous thromboembolism (VTE) in patients with cervical cancer. We selected 49,514 newly diagnosed cancer from the Korean Health Insurance Review Assessment Service databases. During total follow-up period first 6 months after initiation of primary treatments, VTE, association VTE occurrence were evaluated according to treatments or no treatment, surgery, radiotherapy, chemotherapy. occurred 1.15% Regardless was highest 12...
Abstract Background In women with newly diagnosed ovarian cancer, bevacizumab and poly (ADP-ribose) polymerase inhibitors (PARPi) exhibit improved progression-free survival (PFS) when administered concurrent chemotherapy and/or maintenance therapy, but no study has directly compared their effects. Therefore, this aimed to compare the efficacy safety of PARPi in cancer using a network meta-analysis. Methods PubMed, Medline, Embase databases were searched, five randomized trials assessing PFS...
The effect of postoperative hormone replacement therapy (HRT) on survival in women with ovarian cancer remains unclear. This study aimed to investigate the impact HRT using nationwide cohort study. Women aged ≤60 and diagnosed that received primary surgery were followed-up for 5.6 ± 2.9 years. Mean ages administered (the group; n = 263) or not control 1521) 41.5 8.5 41.0 11.4 years, respectively. After adjustment covariables, OS was significantly greater group (HR 0.618; 95% CI 0.414−0.922;...
To compare the characteristics of pregnant women with hyperglycemia according to severity glucose intolerance using 100-g oral tolerance test (OGTT) and demonstrate need manage condition mild hyperglycemia.In this retrospective cohort study, a total 258 at high risk gestational diabetes (GDM) based on positive 50-g challenge (OGCT) were classified into 0+, 1+, 2+, 3+, 4+ groups number abnormal plasma values OGTT. The clinical compared.The rates advanced maternal age (≥ 35 years),...
Both threatened miscarriage and gestational diabetes mellitus (GDM) are common complications of pregnancy. However, only one pilot study has reported that these not related. We aimed to investigate whether is the risk factors GDM. An unmatched case-control 1567 pregnant Korean women who underwent a two-step approach diagnose GDM was retrospectively conducted. The eligible were classified into normal (n = 840), borderline 480), 247) groups. analyzed associations with in all groups adjustment...