A5079968599- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Intraperitoneal and Appendiceal Malignancies
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Endometriosis Research and Treatment
- PARP inhibition in cancer therapy
- Renal cell carcinoma treatment
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Cancer Research and Treatments
- Occupational and environmental lung diseases
- Viral-associated cancers and disorders
- BRCA gene mutations in cancer
- Estrogen and related hormone effects
- Colorectal and Anal Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Multiple and Secondary Primary Cancers
- Testicular diseases and treatments
- Ureteral procedures and complications
- Advanced Breast Cancer Therapies
- Mathematical Biology Tumor Growth
- Pancreatic and Hepatic Oncology Research
- Management of metastatic bone disease
- Chemotherapy-induced organ toxicity mitigation
Ajou University
2016-2025
Korea University Medical Center
2023
CHA Bundang Medical Center
2023
CHA University
2023
Seoul National University
2023
Asan Medical Center
2023
Ajou University Hospital
2016-2022
This study aimed to evaluate the therapeutic role of lymphadenectomy in patients surgically treated for clinically early-stage epithelial ovarian cancer (EOC).
Importance Hyperthermic intraperitoneal chemotherapy (HIPEC) followed by interval cytoreductive surgery (ICS) has shown survival benefits for patients with advanced-stage ovarian cancer. However, there is still a lack of consensus regarding the integration HIPEC into clinical practice. Objective To evaluate safety and effectiveness ICS compared alone in practice Design, Setting, Participants This prospective, multicenter, comparative cohort study enrolled 205 stage III or IV cancer who had...
We updated the Korean Society of Gynecologic Oncology (KSGO) practice guideline for management ovarian cancer as version 5.1. The team KSGO published announced fifth (version 5.0) its clinical guidelines in December 2023. In 5.0, selection key questions and systematic reviews were based on data available up to 2022. Therefore, we 5.0 with newly accumulated added 5 new reflecting latest insights field between 2023 2024. For each question, recommendation was provided together corresponding...
The purpose of this study is to investigate the incidence lymph node metastasis in early endometrial cancer patients and evaluate preoperative clinicopathological factors predicting metastasis.We identified 142 with between January 2000 February 2013. All demonstrated endometrioid adenocarcinoma grade 1 or 2 on biopsy. Preoperative magnetic resonance imaging showed that tumors were confined uterine corpus superficial myometrial invasion (less than 50%), there no nodes enlargements. had...
In the 2023 series, we summarized major clinical research advances in gynecologic oncology based on communications at conference of Asian Society Gynecologic Oncology Review Course. The review consisted 1) Endometrial cancer: immune checkpoint inhibitor, antibody drug conjugates (ADCs), selective inhibitor nuclear export, CDK4/6 inhibitors WEE1 poly (ADP-ribose) polymerase (PARP) inhibitors. 2) Cervical surgery low-risk early-stage cervical cancer, therapy for locally advanced stage and...
Introduction We evaluated the effect of high-dose polymeric nanoparticle micellar paclitaxel (PM-Pac) on survival in patients with stage III-IV high-grade serous ovarian cancer (HGSC) who underwent upfront surgery. Methods prospectively recruited received PM-Pac (280 mg/m 2 ) and carboplatin at an area under curve (AUC) 5 (cohort 1) two tertiary centers between October 2015 June 2019. As historical controls, we retrospectively collected data those (175 (AUC 5; cohort 2) or ), 5) bevacizumab...
Objective: To evaluate oncologic outcomes of minimally invasive radical hysterectomy (RH) in early cervical cancer before and after the application parametrial invasion (PMI) criterion on magnetic resonance imaging (MRI) vaginal colpotomy (VC).Methods: A total 216 International Federation Gynecology Obstetrics stage IB-IIA patients who underwent RH was identified between April 2006 October 2018.Patients were classified into pre-PMI intracorporeal or VC (IVC) (n=117) post-PMI groups (n=99).In...
Objective This study aimed to analyze the clinical features of clear cell carcinoma in relation endometriosis and determine an appropriate surveillance strategy for early detection malignant transformation endometrioma asymptomatic patients. Methods We retrospectively reviewed clinicopathologic data 50 patients with ovarian carcinoma. Clinicopathologic characteristics, treatment outcomes, association between risk were analyzed. Results Ten (20%) had been diagnosed before diagnosis The median...
To analyze peritoneal spillage and displacement of indocyanine green (ICG)-stained tissues from uterine cervix to pelvis during intracorporeal/vaginal colpotomy in laparoscopic-assisted hysterectomy.Eleven patients undergoing hysterectomy were included. One patient with an incidental diagnosis endometrial cancer was excluded. Of the 10 patients, five underwent intracorporeal (IC) received vaginal (VC) hysterectomy. Approximately 5 cm resected round ligament each stained ICG cut 1.0 × size....
Abstract Background and Objectives To achieve optimal cytoreduction, extensive bowel resections are sometimes required in patients with advanced ovarian cancer. Few studies have focused on the extent or number of surgeries their feasibility. Methods We retrospectively reviewed medical records cancer who underwent surgery as part debulking procedures at Ajou University Hospital from 2006 to 2018. Patients received (two‐segment subtotal colectomy) were identified, perioperative outcomes...
The aim of this study was to identify high- and low-risk subgroups patients with lymph node (LN) metastasis in presumed early-stage endometrioid endometrial cancer (EC) patients.
Abstract Background This study aims to evaluate the incidence of and identify risk factors for gastrointestinal (GI) genitourinary (GU) fistula or perforation formation with without bevacizumab in patients recurrent cervical cancer who underwent pelvic radiation therapy (RT). Methods Medical records previously RT between 2007 2020 were retrospectively reviewed. Clinicopathological compared groups that are stratified according to: 1) fistula/perforation (+) versus (-); 2) plus conventional...
Abstract Objective To identify the risk factors for failure of first‐line poly (ADP‐ribose) polymerase inhibitor (PARPi) maintenance therapy in patients with advanced ovarian cancer. Method Patients stage III‐IV epithelial cancer who received PARPi were retrospectively reviewed. Clinicopathologic compared between two groups—recur/progression disease (PD) and non‐recur/PD. Results In total, 191 included. Median follow‐up was 9.9 months, recurrence rate 20.9%. BRCA mutations found 63.4%...
(1) Background: Multiple confounding factors influence the indications for secondary cytoreductive surgery (SCS) in patients with ovarian cancer (OC). We aimed to identify associated most likely benefit from SCS. (2) Methods: retrospectively reviewed medical records of recurrent 2003 2021. The potential influencing treatment outcomes and survival between who received chemotherapy alone those SCS after recurrence were evaluated. (3) Results: Recurrent OC was identified 262 patients, a median...
This study aimed to evaluate early clinicopathologic factors predicting gross residual disease after neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer.We analyzed data of 68 cancer who were treated followed by interval debulking surgery (NAC-IDS) between March 2006 and December 2016. All the received three cycles NAC IDS. We evaluated all possible characteristics, including reduction rates serum CA-125 each seven initial abdominopelvic computed tomography (CT)...
There have been no studies concerning the complications or benefits of cholecystectomy in ovarian cancer. In this study, we aimed to evaluate outcomes performed during various time periods disease course and suggest a management strategy for cancer.We retrospectively reviewed medical records patients with advanced cancer who underwent cytoreductive surgery from 2009 2020. Cholecystectomy was primarily indicated when gallbladder surrounding structures were considered metastatic tumor...