A5059988723- Hip and Femur Fractures
- Cannabis and Cannabinoid Research
- Ultrasound and Hyperthermia Applications
- Trauma and Emergency Care Studies
- COVID-19 Clinical Research Studies
- Clinical Nutrition and Gastroenterology
- Abdominal Surgery and Complications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Schizophrenia research and treatment
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Cerebrospinal fluid and hydrocephalus
- Hernia repair and management
- Diet and metabolism studies
- Pharmacovigilance and Adverse Drug Reactions
- RNA and protein synthesis mechanisms
- Antibiotic Use and Resistance
- Pancreatitis Pathology and Treatment
- Pregnancy-related medical research
- Traumatic Brain Injury and Neurovascular Disturbances
- Influenza Virus Research Studies
- Lipoproteins and Cardiovascular Health
- Berberine and alkaloids research
- Cardiac, Anesthesia and Surgical Outcomes
- Blood transfusion and management
Nanjing Drum Tower Hospital
2019-2024
Nanjing University of Chinese Medicine
2024
Nanjing Medical University
2023
Nanjing University
2013
Nanjing General Hospital of Nanjing Military Command
2013
Uncontrolled 'cytokine storms' and multiple organ dysfunction syndrome (MODS) are important causes that leading to progression of illness death in patients with COVID-19 1,2 .The gut is a major invaded damaged by severe acute respiratory coronavirus 2 (SARS-CoV-2), plays vital role controlling the systemic inflammatory response preventing MODS.Berberine has long history traditional Chinese medicine for treatment diarrhoea gastroenteritis owing its antimicrobial, antimotility antisecretory...
Coagulation dysfunction is an evident factor in the clinical diagnosis and treatment of patients with coronavirus disease 2019 (COVID-19), appearing even COVID-19 normal inflammation indices. Therefore, this study aimed to analyze characteristics coagulation function indices investigate possible mechanisms through comparison non-severe severe patients.We included 143 whose characteristics, function, other such as inflammatory factors were collected compared based on severity.Activated...
The current gold standard for the clinical diagnosis of portal hypertension (PH) is an invasive and indirect estimation vein pressure (PVP). Therefore, need a non-invasive PVP measurement method urgent. Subharmonic scattering ultrasound contrast agent (UCA) microbubbles under investigation in research as indicator. However, driving acoustic must be optimized to improve ambient sensitivity subharmonic amplitude different UCAs. In this study, first time, we obtained relationship between signal...
Recombinant activated factor VIIa (rFVIIa) has been highlighted by correcting uncontrollable traumatic haemorrhage. Compared with routine coagulation tests, thromboelastography (TEG) can evaluate the function of trauma patients more rapidly, accurately and comprehensively, also diagnose trauma-associated coagulopathy (TAC) in an early stage. Thirty-eight cases conforming to rFVIIa indications were screened according TEG results divided into group (n = 20) a nonrFVIIa 18). Their was...
Abstract Background This study examined the feasibility of transabdominal intestinal ultrasonography in evaluating acute gastrointestinal injury (AGI). Methods A total 116 patients were included. Intestinal was conducted daily within 1 week after admission to intensive care unit. Ultrasonography indicators including diameter, changes folds, thickness wall, stratification and peristalsis (movement contents) observed determine (AGIUS) score. The urinary tract sonography ultrasound (GUTS)...
A discussion about the correlation between level of serum sodium and sepsis-induced coagulopathy (SIC).
Extensive research indicates that obesity, defined by a body mass index (BMI) greater or equal to 30, is common in patients treated with antipsychotic drugs and frequently associated carbohydrate lipid abnormalities leading metabolic syndrome diabetes. In contrast, the health of overweight (BMI=25-29.9) without diabetes has not been thoroughly investigated.To assess receiving drugs.We compared standard parameters (BMI; waist circumference; hemoglobin A1c; fasting lipids; post-challenge...
This study aimed to identify the long-term D-dimer trajectory patterns and their associations with in-hospital all-cause mortality in abdominal trauma patients. is a retrospective cohort of general adult patients admitted Jinling Hospital (Nanjing, China) between January 2010 April 2020. Group-based modeling was applied model trajectories over first 50 days post-trauma. A multivariable logistic regression performed estimate mortality. total 309 were included. We identified four distinct...
Severe pneumonia caused by influenza virus infection can be secondary to invasive pulmonary fungal (IPF) infection. This study aimed summarize the incidence of IPF and further explore its etiologic mechanism high-risk factors. All adult patients with confirmed A (H1N1) admitted intensive care units (ICUs) Nanjing Drum Hospital from November 2017 March 2018 were retrospectively selected. The differences in baseline factors, risk immune function outcome parameters studied between without IPF....
To explore the predictive value of lipoproteins on progression critically ill patients to chronic critical illness (CCI).
Background Sepsis-associated liver dysfunction (SALD) has high incidence and mortality in patients with intra-abdominal infection (IAI). The associations between acute gastrointestinal injury (AGI), gut microbiota, SALD were evaluated IAI. Methods A retrospective study was conducted to assess the relationship AGI Patients divided into non-SALD sepsis-induced cholestasis ( SIC ) groups, which is a subtype of SALD. defined as total bilirubin >2 mg/dL. incidences two groups compared...
To investigate the incidence and risk factors of polymyxin B-associated acute kidney injury (AKI) in patients with severe infections caused by extensive drug resistance Gram negative bacteria (XDR-GNB) intensive care unit (ICU).A retrospective study adult infection who received B for more than 3 days department critical medicine Nanjing Drum Tower Hospital Affiliated to University Medical School from April 1st 2018 January 31st 2020 were performed. AKI was diagnosed Kidney Disease: Improving...
Massive pulmonary haemorrhage can spoil the entire lung and block airway in a short period of time due to severe bleeding, which quickly leads death. Alveolar lavage is an effective method for haemostasis maintenance. However, patients often cannot tolerate alveolar hypoxia. We used extracorporeal membrane oxygenation (ECMO) overcome this limitation patient with massive trauma succeeded saving life by repeated lavage.A 22-year-old man sustained multiple injuries motor vehicle accident was...
Overweight and moderate obesity confer a survival benefit in chronic diseases such as coronary artery disease kidney disease, which has been termed the "obesity paradox". However, whether this phenomenon exists trauma patients remains controversial. We performed retrospective cohort study abdominal admitted to Level I center Nanjing, China between 2010 2020. In addition traditional body mass index (BMI) based measures, we further examined association composition-based indices with clinical...
To evaluate the relationship between acute muscle wasting rate and long-term mortality in critically ill trauma.
Correlation between nonlinear subharmonic scattering of ultrasound contrast agent microbubbles and ambient pressure is expected to be used for local brain tissue monitoring. Although high-frequency has achieved high-resolution imaging intracranial microvessels, the research on characteristics insufficient at present, which restricts progress estimating based microbubbles. Therefore, under excitation 10 MHz ultrasound, effects different acoustic pressures three agents including SonoVue,...