A5101804454- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Physics of Superconductivity and Magnetism
- Magnetic properties of thin films
- Circular RNAs in diseases
- Theoretical and Computational Physics
- Quantum and electron transport phenomena
- Autophagy in Disease and Therapy
- Plant biochemistry and biosynthesis
- Cholesterol and Lipid Metabolism
- Cardiac Fibrosis and Remodeling
- Atrial Fibrillation Management and Outcomes
- Inorganic Chemistry and Materials
- Advanced Chemical Physics Studies
- MicroRNA in disease regulation
- Adipokines, Inflammation, and Metabolic Diseases
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Cancer Mechanisms and Therapy
- IL-33, ST2, and ILC Pathways
- Plant Virus Research Studies
- Signaling Pathways in Disease
- Radiomics and Machine Learning in Medical Imaging
- Hydrocarbon exploration and reservoir analysis
- Cardiac Ischemia and Reperfusion
Nanjing University of Chinese Medicine
2016-2025
Xiamen University
2024
Inner Mongolia University of Technology
2024
Research Center for Eco-Environmental Sciences
2024
Chinese Academy of Sciences
2024
China Medical University
2024
State Forestry and Grassland Administration
2024
Jiangxi Academy of Forestry
2019-2024
Jiangsu Provincial Academy of Traditional Chinese Medicine
2020-2024
First Hospital of China Medical University
2024
Summary In this study, we report new insights into the function of a wheat ( T riticum aestivum ) MYB gene Ta PIMP 1 through overexpression and underexpression , its underlying mechanism in wheat. Electrophoretic mobility shift yeast‐one‐hybrid assays indicated that can bind to five ‐binding sites including ACI activate expression genes with cis ‐element, confirming is an transcription activator. 1‐ overexpressing transgenic exhibited significantly enhanced resistance fungal pathogen B...
Abstract Sulforaphane, a naturally occurring compound found in cruciferous vegetables, has been shown to be neuroprotective several neurological disorders. In this study, we sought investigate the potential protective effects and associated molecular mechanisms of sulforaphane an vivo Parkinson’s disease (PD) model, based on rotenone-mediated neurotoxicity. Our results showed that inhibited rotenone-induced locomotor activity deficiency dopaminergic neuronal loss. Additionally, treatment...
Reactive oxygen species (ROS) produced in the ischemic myocardium can induce cardiomyocyte injury and death, resulting cardiac remodeling. Ferroptosis, known as a newly type of cell death caused by iron-dependent oxidative stress, which is an essential mechanism cardiomyocytes. However, it unclear whether stress products further ferroptosis aggravate injury. Geniposide (GEN), major active component Gardenia jasminoides J. Ellis , possesses natural antioxidant activity cardioprotective...
Myocardial ischemia/reperfusion injury (MIRI) is related to ferroptosis and apoptosis elicited by reactive oxygen species (ROS). In this research, we investigated the protective effect of salvianolic acid B (SAB) as a natural antioxidant on in MIRI process, discussed mechanism inhibiting ubiquitin-proteasome degradation glutathione peroxidase 4 (GPX4) c-Jun N-terminal kinases (JNK) signal pathway. We observed that occurred rat model vivo H9c2 cardiomyocyte hypoxia/reoxygenation (H/R) damage...
Cinnamomum camphora is a traditional aromatic plant used to produce linalool and borneol flavors in southern China; however, its leaves also contain many other unutilized essential oils. Herein, we report geographic relationships for the yield compositional diversity of C. The oils 974 individual trees from 35 populations 13 provinces were extracted by hydrodistillation analyzed qualitatively quantitatively gas chromatography-mass spectrometry chromatography-flame ionization detection,...
Abstract Vascular endothelial cells (VECs) are located between the blood plasma and vascular tissue, ferroptosis (iron‐dependent programmed cell death) of VECs can lead to a range cardiovascular diseases. Icariin is main active ingredient Epimedium brevicornum Maxim., which improve dysfunction. In present study, protective effects icariin on oxidised low‐density lipoprotein (ox‐LDL)‐treated high‐fat diet‐fed Apolipoprotein E‐deficient mice were investigated. Inflammatory fibrosis in tissues...
The induction of ferroptosis is promising for cancer therapy. However, the mechanisms enabling cells to evade ferroptosis, particularly in low-cystine environments, remain elusive. Our study delves into intricate regulatory Activating transcription factor 3 (ATF3) on Cystathionine β-synthase (CBS) under cystine deprivation stress, conferring resistance colorectal (CRC) cells. Additionally, our findings establish a positively correlation between this signaling axis and CRC progression,...
In this paper, a multiple-scattering formalism for electromagnetic waves is presented. Its application to the three-dimensional periodic dielectric structures given in form similar usual Korringa-Kohn-Rostoker of scalar waves. Using approach, band-structure results touching spheres diamond structure medium with constant 12.96 are calculated. The disordered systems under coherent-potential approximation discussed.
As an important member of the interleukin (IL)-1 family, IL‑33 plays a significant role in tumor progression. To explore this, we previously analyzed association between expression and prognosis patients with glioma. However, function IL‑33/ST2 axis glioma remained unclear. In present study, immunofluorescent staining results revealed that levels ST2 receptor tissues were higher than those normal brain tissues. Invasion migration assays demonstrated significantly increased cell invasion...
Abstract Background Nutritional deficiencies (ND) continue to threaten the lives of millions people around world, with children being worst hit. Nevertheless, no systematic study epidemiological features child ND has been conducted so far. Therefore, we aimed comprehensively assess burden pediatric ND. Methods We analyzed data on between 1990 and 2019 from Global Burden Disease (GBD) at global, regional, national levels. In addition, joinpoint regression models were used temporal trends....
The generalized susceptibility for rare-earth nickel boride carbides has been calculated using the normal-state electronic structure. Peaks in occur near wave vectors corresponding to those observed incommensurate spin density waves ${\mathrm{HoNi}}_{2}$${\mathrm{B}}_{2}$C between approximately 4.7 and 6.0 K [A. I. Goldman et al., Phys. Rev. B 50, 9668 (1994)].
We have calculated the electronic structure of spin-dependent tunneling structures, Fe|Ge|Fe and Fe|GaAs|Fe, using first principles techniques. find that there is a large charge transfer from metal layer to semiconductor layer; 0.21 electrons are transferred Fe Ge 0.27 GaAs at each interface. The density states interfacial dramatically different other layers; peak in Fermi energy for minority electrons. quite majority spins although its total magnetic moment negligible. Our results suggest...
Loan behavior modeling is crucial in financial engineering. In particular, predicting loan prepayment based on large-scale historical time series data of massive customers challenging. Existing approaches, such as logistic regression or nonparametric regression, could only model the direct relationship between features and prepayments. Motivated by extracting hidden states behavior, we propose smoothing spline state space (QuadS) a Markov with varying transition emission matrices modeled...
Background Ischemic heart disease (IHD) places a heavy burden on individual and public health. Nevertheless, comprehensive assessments of the IHD in elderly are absent. It is imperative to update older adults predict trends. Methods The absolute numbers age-standardized rates (ASRs) prevalence, mortality, disability-adjusted life-years (DALYs) for among people aged 60–89 years from 1990 2019 were analyzed based Global Burden Disease Study (GBD 2019). Joinpoint regression analysis was...
Leaves of C. porrectum are rich in essential oils containing monoterpenes, sesquiterpenes and aromatic compounds, but the molecular mechanism terpenoid biosynthesis is still unclear. In this paper, differences contents compositions terpenoids among three chemotypes were analyzed using gas chromatography mass spectrometry (GC/MS). Furthermore, differential expression gene transcripts leaf tissues through a comparison full-length transcriptomes profiles. The oil leaves was mainly composed...
Existing studies have indicated that gut microbiota is closely related to the occurrence and development of coronary heart disease(CHD). Gut its metabolites may be important diagnostic markers for CHD in future are expected become new targets prevention treatment CHD. However, current exploring link between miscellaneous poorly targeted, without bibliometric analysis available.The purpose this research was perform a visual published papers on relationship microbiota. The study also sought...
Cinnamomum species attract attentions owing to their scents, medicinal properties, and ambiguous relationship in the phylogenetic tree. Here, we report a high-quality genome assembly of camphora, based on which two whole-genome duplication (WGD) events were detected C. camphora genome: one was shared with Magnoliales, other unique Lauraceae. Phylogenetic analyses illustrated that Lauraceae formed compact sister clade eudicots. We then performed resequencing 24 native China, results showed...