A5085752809- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Head and Neck Anomalies
- Diabetes Management and Research
- Thyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Pancreatic function and diabetes
- Myasthenia Gravis and Thymoma
- Intraocular Surgery and Lenses
- Diabetes and associated disorders
- Skin Diseases and Diabetes
- Oropharyngeal Anatomy and Pathologies
- Diet and metabolism studies
- Vitamin D Research Studies
- Thyroid Cancer Diagnosis and Treatment
- Maternal and fetal healthcare
- Teratomas and Epidermoid Cysts
- Dermatological and COVID-19 studies
- Retinal and Macular Surgery
- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Ophthalmology and Eye Disorders
- Nutrition and Health in Aging
Universidad Cardenal Herrera CEU
2018-2025
Hospital General Universitari de Castelló
2012-2024
Hospital General de Elda
2018
Hospital Universitari i Politècnic La Fe
2006-2009
Few data exist about the clinical course of acromegaly, surgical and medical outcomes in patients with GH- prolactin cosecreting pituitary adenomas (GH&PRL-PAs). Nevertheless, some series described a more aggressive clinic-radiological behavior than growth hormone-secreting (GH-PAs).
Chronic kidney disease (CKD) patients show high rates of cardiovascular (CVD) and mortality. In the general population, obesity, hypertension, diabetes are known as classical CVD risk factors. However, CKD have other predisposing factors more associated with bone mineral metabolism disorders (BMD). BMD originates from reduced 1,25-dihydroxy vitamin D hypocalcemia, which lead to secondary hyperparathyroidism, increased parathyroid hormone (PTH) levels hyperphosphatemia progression renal...
Hyperintensity signal in T2-weighted magnetic resonance imaging (MRI) has been related to better therapeutic response during pasireotide treatment acromegaly. The aim of the study was evaluate T2 MRI intensity and its relation with effectiveness real-life clinical practice.Retrospective multicentre including acromegaly patients treated pasireotide. Adenoma at diagnosis qualitatively classified as iso-hyperintense or hypointense. Insulin-like growth factor (IGF-I), hormone (GH) tumour volume...
The objective of the study was to evaluate efficacy second-line therapies in patients with acromegaly caused by a growth hormone (GH) and prolactin (PRL) co-secreting pituitary neuroendocrine tumor (GH&PRL-Pit-NET) compared their GH-secreting (GH-Pit-NET). This is multicenter retrospective on treatment pasireotide and/or pegvisomant. Patients were classified two groups: GH&PRL-Pit-NETs when evidence hyperprolactinemia immunohistochemistry (IHC) for GH PRL positive or if >200 ng/dL regardless...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
The aim of this study is to compare the response first-line medical treatment in treatment-naive acromegaly patients with pure growth hormone (GH)-secreting pituitary adenoma (GH-PA) and those GH prolactin cosecreting PA (GH&PRL-PA).
To analyze the usefulness of plasma ACTH in predicting CD remission after surgery and to evaluate prognostic measurement cortisol nadir (48 h prior discharge).A prospective study was made 65 patients with operated upon between 2005 2016.Postsurgery were measured every 6 h, absence corticosteroid coverage. Hydrocortisone started presence adrenal insufficiency or <55.2 nmol/L. Plasma again determined before discharge.Usefulness remission.Remission at 3 months achieved 56 cases, late recurrence...
Basal insulin reduces fasting blood glucose levels, but postprandial levels may remain higher. Traditional strategies with rapid intensification can cause hypoglycemic episodes and weight gain. Glucagon-like peptide-1 receptor agonists, such as the short-acting lixisenatide, are able to control excursions, without gain, a low risk of events. Due limited data on combination lixisenatide basal (with or oral antidiabetes drugs) in clinical practice, this study evaluated changes parameters...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
<title>Abstract</title> <bold>Aim:</bold> To investigate the impact of pituitary surgery on glucose metabolism and to identify predictors remission diabetes after in patients with acromegaly. <bold>Methods: </bold>A national multicenter retrospective study acromegaly undergoing transsphenoidal for first time at 33 tertiary Spanish hospitals (ACRO-SPAIN study) was performed. Surgical evaluated according 2000 2010 criteria. <bold>Results: total 604 were included a median follow up 91 months...
Aims: To evaluate the metabolic and clinical outcomes in Spanish type 1 diabetes mellitus (T1D) population before after COVID-19 vaccination. Methods: A retrospective observational study was carried out public hospitals previously enrolled SED1 study. Adults children with T1D were included their electronic records reviewed. Clinical, laboratory, glucometric parameters from continuous glucose monitoring (CGM) data corresponding to periods administering first vaccination analyzed. Results:...
Thyroid hormone (TH) resistance syndrome is a genetic disorder usually caused by defect in TH receptors. Moreover, transport and intracellular metabolism alterations have also been described. This case report presents child with Allan–Herndon–Dudley characterized mutation on the X-linked monocarboxylate transporter 8 gene, condition that affects of THs across cell membrane, leading to hypothyroidism central nervous system hyperthyroidism peripheral tissues, causing severe neurodevelopmental...